Cubs vs. Pirates Odds & Betting Predictions - May 25, 2026

Cubs at Pirates

5:35 pm • SportsNet PT
1 - 2
Starting Pitchers
pitcherteameraw-l
Carmen Mlodzinski logoC.MlodzinskiPittsburgh Pirates logo3.877-6
Ben Brown logoB.BrownChicago Cubs logo1.854-2

Cubs at Pirates Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Cubs
81-66
-1.5
-1.5+134
o8.5-109
-124
Pirates
73-73
u8
+1.5-162
u8.5-110
+105
location pinMonday 5:35 p.m.
May 25, 2026
PNC ParkPittsburgh
Cubs vs. Pirates Expert Picks
Wags Wins
Wags Wins
Last 30d: 222-172-3 (+35.9u)
CHC -125
2u
OldSchool0909
Last 30d: 75-91-1 (-13.3u)
PIT +113
1.13u
Frank Ammirante
Frank Ammirante
Last 30d: 278-341-7 (-50.8u)
B.Brown o5.5 Ks+121
1u
Adam Kaufman
Adam Kaufman
Last 30d: 85-99-0 (-29.8u)
PIT -104
1u
Sean Zerillo
Sean Zerillo
Last 30d: 51-82-3 (-7.8u)
CHC -110
0.55u
Bet to -120

Cubs vs. Pirates Previews & Analysis

  • The Leadoff: Anderson's MLB Breakdown & Bets for Monday article feature image

    The Leadoff: Anderson's MLB Breakdown & Bets for Monday

    Jon Anderson
    May 25, 2026 UTC
  • Zerillo's Projection for Cubs-Pirates article feature image

    Zerillo's Projection for Cubs-Pirates

    Tanner McGrath
    May 25, 2026 UTC
  • +300, +470, +520 Data Model HR Picks article feature image

    +300, +470, +520 Data Model HR Picks

    Alex Kolodziej
    May 25, 2026 UTC
See more MLB Coverage Right Arrow

Prop Odds Comparison

Right Arrow
Right Arrow

No props found

Line Movement Tracker

Right Arrow
Right Arrow

Cubs vs. Pirates Public Betting Percentages

Away Logo

Cubs

Public

58%

Bets%

42%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Pirates
70-7633-3937-3734-4235-32
Cubs
71-7631-4140-3543-5527-20

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Pirates
75-66-543-27-232-39-343-31-230-34-3
Cubs
81-6640-3241-3454-4426-21

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Pirates
73-7338-3435-3942-3430-37
Cubs
81-6641-3140-3556-4223-24

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 24th@TORW 4-1+1.5 WU 7.5PIT +145
May 23rd@TORL 2-5-1.5 LU 7.5TOR -144
May 22nd@TORL 2-6+1.5 LU 8TOR +137
May 21st@STLW 6-2-1.5 WO 7PIT -121
May 20th@STLW 7-0-1.5 WU 7.5PIT -103

Pirates vs. Cubs Injury Updates

Pirates Injuries

    Cubs Injuries

    • Tyler Austin
      1B

      Austin is out with knee

      Out

    • Justin Steele
      SP

      Steele is out with elbow

      Out

    Cubs vs. Pirates Box Score
    Cubs Player Stats
    Projected
    PITCHERPCIPKER
    Ben Brown logoRB.Brown, P83671
    Trent Thornton logoRT.Thornton, P21101
    Jacob Webb logoRJ.Webb, P23120
    HITTERSH-ABRHRRBI
    Pete Crow-Armstrong logo1P.Crow-Armstrong, CF0-4000
    Ian Happ logo2I.Happ, LF0-3000
    Michael Busch logo3M.Busch, 1B1-4111
    Alex Bregman logo4A.Bregman, 3B2-4000
    Michael Conforto logo5M.Conforto, RF0-4000
    Pedro Ramirez logo6P.Ramirez, 2B1-3000
    Nico Hoerner logo6N.Hoerner, PH0-1000
    Moises Ballesteros logo7M.Ballesteros, DH2-2000
    Seiya Suzuki logo7S.Suzuki, PH0-1000
    Miguel Amaya logo8M.Amaya, C0-2000
    Carson Kelly logo8C.Kelly, PH0-1000
    Dansby Swanson logo9D.Swanson, SS0-3000
    Pirates Player Stats
    Projected
    PITCHERPCIPKER
    Carmen Mlodzinski logoRC.Mlodzinski, P86521
    Wilber Dotel logoRW.Dotel, P41340
    Gregory Soto logoLG.Soto, P14110
    HITTERSH-ABRHRRBI
    Spencer Horwitz logo1S.Horwitz, 1B2-3100
    Brandon Lowe logo2B.Lowe, 2B2-4001
    Bryan Reynolds logo3B.Reynolds, RF1-4000
    Nick Gonzales logo4N.Gonzales, 3B0-4000
    Oneil Cruz logo5O.Cruz, CF2-4000
    Marcell Ozuna logo6M.Ozuna, DH0-4000
    Konnor Griffin logo7K.Griffin, SS0-3000
    Jhostynxon Garcia logo8J.Garcia, LF0-3000
    Henry Davis logo9H.Davis, C1-3111

    Cubs vs. Pirates Odds Comparison

    Right Arrow

    Could not load odds

    Cubs at Pirates Team Totals

    MatchupOverUnder
    Cubs
    81-66
    N/A
    N/A
    Pirates
    73-73
    N/A
    N/A