Yankees vs. Guardians Odds & Betting Predictions - April 22, 2025

Yankees at Guardians

10:10 pm • CLEG

New York Yankees

3-4

2 - 3

Cleveland Guardians

1-2

pitcher		team	era	w-l
T.Bibee			4.25	12-11
W.Warren			4.43	9-8

MatchupOpenSpreadTotalMoneyline
Yankees 3-4	-1.5	-1.5+164	o8.5-105	+102
Guardians 1-2	u8	+1.5-192	u8.5-115	-120

Tuesday 10:10 p.m.

April 22, 2025

Progressive FieldCleveland

Over 8.5-115

1.15u

NYY -113

2.26u

K.Manzardo o0.5 HR+575

0.5u

J.Ramirez o0.5 HR+560

0.97u

Under 8+100

Guardians offense light – 4.18 runs/game, .235 AVG overall, .237 vs RHP. Warren keeps it on the ground – 2.00 GB/FB ratio limits big innings. Progressive Field low scoring – just 7.3 total runs/game. Early season trends lean low-scoring battle. Yankees bullpen in form – 2.45 ERA, 1.03 WHIP over last 3, 33 Ks in 33 IP. Starters likely won’t go deep, so pens matter. Both squads have reliable late arms. If this stays tight, expect minimal scoring from the 6th on. Yankees offense can flash but still averaging just 5.65 runs. Guardians stingy at home – 1.86 ERA, 6-1 at Progressive. Past 8 for Yankees hit the under in 5. Low tempo, contact-heavy matchups, both teams capable of limiting damage.

NYY -105

Yankees’ pen rolling – 2.45 ERA, 1.03 WHIP over last 33 IP. Full unit at 3.30 ERA, 1.15 WHIP on the year – deeper, sharper group than Cleveland’s. If it's close late, edge clearly NY. Warren solid enough – 2.00 GB/FB ratio, limits HRs, team 2-1 in his last 3. Guardians hitting just .237 vs RHP, so he’s in a good spot to keep them quiet. Just needs to go 5+ and hand it off. Cleveland offense doesn’t scare, especially if it’s tight early. Bibee in a rough patch – 8.16 ERA, 7 HR allowed last 14.1 IP. Yankees will attack. Judge leading the charge (.494 xwOBA, 59.4% Hard Hit). NY hitting .252 vs RHP, averaging 5.65 runs/game – more firepower across the board. They’ve won 15 of last 22 in Cleveland.

NYY o4.5 Team Total+105

0.95u

J.Dominguez o0.5 HR+870

0.1u

Under 8.5-125

1.08u

T.Bibee u5.5 Ks+115

0.49u

Tailing @TurveyBets

T.Bibee u5.5 Ks+115

0.63u

CLE -112

0.89u

Zerillo's Wednesday MLB Predictions & Betting Card
Sean Zerillo•
Apr 23, 2025 UTC
Yankees vs. Guardians: Tuesday Night SGP
Dead President Picks•
Apr 22, 2025 UTC
Target These MLB Player Props on Tuesday
Alex Hinton•
Apr 22, 2025 UTC
4 Home Run Prop Bets for Tuesday Night
Grant Neiffer•
Apr 22, 2025 UTC

See more MLB Coverage

No props found

MLB Public Betting

Guardians are 3-2 in their last 5 games.
Guardians are 1-4 in their last 5 games against the spread
Guardians are 47-34 in their road games against the spread
The totals have gone OVER in 2 of Guardians' last 5 games
The totals have gone OVER in 37 of Guardians' 81 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Guardians	86-76	39-42	47-34	33-36	51-38
Yankees	78-84	43-38	35-46	68-72	9-12

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Guardians	69-87-6	37-41-3	32-46-3	34-34-1	34-50-5
Yankees	76-81-5	36-44-1	40-37-4	64-73-3	11-8-2

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Guardians	88-74	45-36	43-38	44-25	43-46
Yankees	94-68	50-31	44-37	85-55	8-13

date	opponent	score	spread	over/under	moneyline
Apr 21st	NYY	W 6-4	+1.5 W	O 8.5	CLE +110
Apr 20th	@PIT	W 5-4	-1.5 L	O 8	CLE +105
Apr 19th	@PIT	W 3-0	+1.5 W	U 8	CLE +145
Apr 18th	@PIT	W 10-7	-1.5 W	O 9	CLE -130
Apr 17th	@BAL	L 2-6	+1.5 L	U 8	BAL +116

Gerrit Cole
SP
Cole is out for season with elbow
Out for Season

See more MLB Injuries

PITCHER	PC	IP	K	ER
RW.Warren, P	82	5	5	2
RM.Leiter, P	21	0.2	1	1
LT.Hill, P	8	1.1	0	0
RL.Weaver, P	12	1	0	0

HITTERS	H-AB	R	HR	RBI
1B.Rice, DH	1-4	1	1	1
2A.Judge, RF	4-4	1	0	0
3C.Bellinger, CF	0-4	0	0	0
4P.Goldschmidt, 1B	1-3	0	0	0
5J.Chisholm, 2B	0-1	0	0	1
6A.Volpe, SS	0-3	0	0	0
7J.Dominguez, LF	0-4	0	0	0
8J.Escarra, C	0-2	0	0	0
8P.Reyes, PH	0-1	0	0	0
8A.Wells, C	0-1	0	0	0
9O.Cabrera, 3B	0-4	0	0	0

PITCHER	PC	IP	K	ER
RT.Bibee, P	106	6	5	2
LT.Herrin, P	14	1	2	0
RH.Gaddis, P	22	1	2	0
RC.Smith, P	4	1	0	0

HITTERS	H-AB	R	RBI
1S.Kwan, LF	2-4	1	0
2N.Jones, RF	1-3	1	0
2G.Arias, PH	0-1	0	0
2G.Arias, 2B	0-1	0	0
3J.Ramirez, 3B	0-4	0	0
4K.Manzardo, DH	1-4	1	1
5C.Santana, 1B	0-4	0	0
6B.Naylor, C	0-3	0	0
7A.Martinez, CF	1-3	0	1
8D.Schneemann, 2B	1-2	0	0
8D.Schneemann, RF	1-2	0	0
9B.Rocchio, SS	0-3	0	0