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Red Sox vs Orioles Prediction, Pick, MLB Odds for Sunday, April 26

Red Sox vs Orioles Prediction, Pick, MLB Odds for Sunday, April 26 article feature image
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Tim Vizer-Imagn Images. Pictured: Red Sox SP Connelly Early

The Baltimore Orioles host the Boston Red Sox on April 26, 2026. First pitch from Oriole Park at Camden Yards is scheduled for 1:35 p.m. ET. The game will be broadcast on NESN+.

The Orioles are favored by -145 on the moneyline and by -1.5 on the run line. The Red Sox are +120 on the moneyline and +1.5 on the run line. The total is set at 7.5 runs.

Find our MLB picks and Red Sox vs Orioles prediction below, as well as probable pitchers, weather report, and more.


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Red Sox vs Orioles Prediction

  • Red Sox vs Orioles Pick: Under 7.5 (+100)

Our Red Sox vs Orioles best bet is Under 7.5 total runs in this game. Make sure to find the best odds by checking our live MLB odds page.


Red Sox vs Orioles Odds

Red Sox Logo
Sunday, Apr 26
1:35 p.m. ET
NESN+
Orioles Logo
Red Sox Odds
SpreadTotalMoneyline
+1.5
-190
7.5
-120o / 100u
+120
Orioles Odds
SpreadTotalMoneyline
-1.5
+155
7.5
-120o / 100u
-145
Odds via BetMGM. Get up-to-the-minute MLB odds here.
BetMGM Logo
  • Red Sox vs Orioles moneyline: Red Sox +120, Orioles -145
  • Red Sox vs Orioles over/under: 7.5 (-120o / +100u)
  • Red Sox vs Orioles spread: Red Sox +1.5 (-190), Orioles -1.5 (+155)

Red Sox vs Orioles Probable Pitchers

LHP Connelly Early (BOS)StatRHP Kyle Bradish (BAL)
1-1W-L1-2
0.3fWAR (FanGraphs)0.5
2.88 / 5.73ERA / xERA3.96 / 3.71
4.19 / 4.41FIP / xFIP3.51 / 3.79
10.3K-BB%13.0
44.8GB%47.2
.277BABIP.403
102Stuff+100
92Location+96

Red Sox vs Orioles MLB Betting Preview

Our own Sean Zerillo projects an edge on the total for this matchup

While the consensus line sits at 7.5, Zerillo projects around 6.79 runs for this game, representing a 4.7% edge against the market, making the under the best choice with a B- grade on our system.

As a reminder, you can see all of Zerillo's MLB game projections with an Action PRO Subscription. Find his projected lines every day on the PRO Projections tab.


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Red Sox vs Orioles Pick, Betting Analysis

Of course, Boston was bound to wake up — the same way Garrett Crochet was supposed to finally get on track — and both things happened on Saturday.

Those 17 runs scored yesterday, however, barely helped the Red Sox leave rock bottom and are now next-to-last in wRC+ this season with 84.

Now, they'll face veteran Kyle Bradish, and their offense will probably settle after that sudden burst.

On the other side, the Orioles bats suffer against left-handed pitchers, which is what they'll have in store this afternoon, with Connelly Early taking the mound for Boston.

Baltimore ranks 10th in wRC+ overall, but drops down to the 18th spot against LHP.

The weather will also play a factor. It is expected to be a chilly 56°F at first pitch. When cold air is denser, it significantly reduces ball flight distance.

Also, forecasts show an 8 mph wind blowing in from center field, which is a nightmare for fly-ball hitters and can turn possible home runs into outs.

Pick: Under 7.5 (+100, BetMGM)

Playbook

Red Sox vs Orioles Weather


Get the latest coverage on MLB Weather.
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