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White Sox vs Cubs Prediction, Pick, MLB Odds for Wednesday, August 19

White Sox vs Cubs Prediction, Pick, MLB Odds for Wednesday, August 19 article feature image
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Aug 18, 2026; Chicago, Illinois, USA; Chicago Cubs third baseman Alex Bregman (3) reacts after hitting a walk-off RBI single against the Chicago White Sox during the ninth inning at Wrigley Field. Mandatory Credit: Patrick Gorski-Imagn Images

The Chicago Cubs host the Chicago White Sox on August 19, 2026. First pitch from Wrigley Field is scheduled for 2:20 p.m. EDT. The game will be broadcast on MARQ.

Find my MLB picks and White Sox vs Cubs prediction below, as well as probable pitchers, weather report, and more.


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White Sox vs Cubs Prediction

  • White Sox vs Cubs Pick: Under 7.5 Runs (49c, Kalshi)

White Sox vs Cubs Kalshi MLB Odds


White Sox vs Cubs Probable Pitchers

Sean Newcomb (LHP, CWS)StatClay Holmes (RHP, CHC)
1-3W-L5-5
1.5fWAR (FanGraphs)1.3
2.51 / 3.80ERA / xERA2.56 / 4.01
2.95 / 3.79FIP / xFIP3.40 / 3.73
14.1%K-BB%11.0%
47.7%GB%58.2%
.268BABIP.239
105Stuff+100
97Location+101

White Sox vs Cubs MLB Preview

We're in for another classic Wrigley Wind day on the North Side for this inter-town matchup.

The weather report is calling for 5 MPH winds blowing directly in from center field, alongside relatively cool 75-degree temperatures. At MLB's most wind-receptive park, this could lower the run-scoring environment by 17%, per BallParkPal.

Get the latest coverage on MLB Weather.

Pick: Under 7.5 Runs Scored (49c, Kalshi)

Author Profile
About the Author

Tanner McGrath covers college basketball, college football and Major League Baseball at Action Network. He is a contributor to Payoff Pitch, Action Network’s Major League Baseball betting podcast. He's been working in the space for more than five years with past journalism experience in Canadian collegiate sports, finance and economics. He has an obsession with America East basketball, betting the Miami Marlins and sweating out home underdogs.

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