The Pittsburgh Pirates host the Cincinnati Reds on June 28, 2026. First pitch from PNC Park is scheduled for 1:35 p.m. EDT. The game will be broadcast on SportsNet PT.
The Pirates are favored by -132 on the moneyline and by -1.5 on the run line. The Reds are +112 on the moneyline and +1.5 on the run line. The total is set at 9 runs.
Find my MLB picks and Reds vs Pirates prediction below, as well as probable pitchers, weather report, and more.
Reds vs Pirates Prediction
- Reds vs Pirates Pick: Elly De La Cruz Over 1.5 HRR
My Reds vs Pirates best bet is on Elly De La Cruz. Make sure to find the best odds by checking our live MLB odds page.
Reds vs Pirates Odds
| Reds Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -205 | 9 -104o / -118u | +112 |
| Pirates Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +168 | 9 -104o / -118u | -132 |
- Reds vs Pirates moneyline: Reds +112, Pirates -132
- Reds vs Pirates over/under: 9 (-104 / -118)
- Reds vs Pirates spread: Pirates -1.5 (+168), Reds +1.5 (-205)
Reds vs Pirates Probable Pitchers
| Brady Singer (RHP, CIN) | Stat | Mitch Keller (RHP, PIT) |
|---|---|---|
| 3-6 | W-L | 5-5 |
| 0.0 | fWAR (FanGraphs) | 1.2 |
| 4.81 / 5.47 | ERA / xERA | 4.89 / 4.93 |
| 5.75 / 4.59 | FIP / xFIP | 4.16 / 4.46 |
| 10.3% | K-BB% | 9.8% |
| 41.4% | GB% | 38.9% |
| .305 | BABIP | .289 |
| 91 | Stuff+ | 93 |
| 97 | Location+ | 102 |
Reds vs Pirates MLB Betting Preview
The Pirates will host the Reds on Sunday afternoon in the last of a three-game homestand at PNC Park in Pittsburgh. 30-year-old right-hander Mitch Keller will take the mound for the Pirates, while the Reds plan to trot out righty Brady Singer.
In what has been a very up-and-down 2026 campaign for both starters thus far, I expect Sunday’s contest to deliver plenty of runs.
So, I’m looking toward the player prop markets.
Keller is really struggling, running a 4.89 ERA through 16 outings this season — it’s his worst season since 2021.
He’s also faced this Reds lineup more than a few times, as these teams are divisional rivals. So, we have a solid sample size to consider when handicapping this clash.
Reds vs Pirates Pick, Betting Analysis
Though Elly De La Cruz has just three hits across 19 head-to-head at-bats against Keller, I still think he’s in for a massive day at the plate.
Keller leans primarily on his four-seam fastball, which he throws over 32% of the time. He’s lost some stuff and velocity on the pitch over the past few years, leading to a steady decline in his swing-and-miss rate on the pitch.
While De La Cruz can be strikeout-prone, Keller doesn’t miss as many bats as he used to, which could hurt against an elite fastball slugger. De La Cruz has big-time power from both sides of the plate, especially when high-velocity pitches are left in the zone.
If De La Cruz can stay disciplined at the plate against Keller’s breaking stuff, he should see some hittable in-the-zone fastballs, cashing some props along the way.
Pick: Elly De La Cruz Over 1.5 HRR
