The Seattle Mariners host the Cleveland Guardians on March 29, 2026. First pitch from T-Mobile Park is scheduled for 7:20 p.m. ET. The game will be broadcast on Peacock.
The Mariners are favored by -156 on the moneyline and by -1.5 on the run line. The Guardians are +129 on the moneyline and +1.5 on the run line. The total is set at 7.5 runs.
Find my MLB picks and Guardians vs Mariners prediction below, as well as probable pitchers, weather report, and more.
Guardians vs Mariners Prediction
- Guardians vs Mariners Pick: Over 7.5 (-112)
My Guardians vs Mariners best bet is Over 7.5 total runs in this game. Make sure to find the best odds by checking our live MLB odds page.
Guardians vs Mariners Odds
| Guardians Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -163 | 7.5 -112o / -108u | +129 |
| Mariners Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +135 | 7.5 -112o / -108u | -156 |
- Guardians vs Mariners spread: Guardians +1.5 (-163), Mariners -1.5 (+135)
- Guardians vs Mariners over/under: Over 7.5 (-112), Under 7.5 (-108)
- Guardians vs Mariners moneyline: Guardians +129, Mariners -156
Guardians vs Mariners Polymarket Odds
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Guardians vs Mariners Projected Starting Pitchers
| RHP Slade Cecconi (CLE) | 2025 Stats | RHP Emerson Hancock (SEA) |
|---|---|---|
| 7-7 | W-L | 4-5 |
| 0.7 | fWAR (FanGraphs) | 0.0 |
| 4.30 / 5.00 | ERA / xERA | 4.90 / 5.52 |
| 4.64 / 4.09 | FIP / xFIP | 5.08 / 4.61 |
| 1.19 | WHIP | 1.38 |
| 14.1 | K-BB% | 8.6 |
| 41.3 | GB% | 43.0 |
| 93 | Stuff+ | 90 |
| 105 | Location+ | 100 |
Guardians vs Mariners Betting Preview
Cleveland Guardians Betting Preview
The Guardians were able to pull through in extra innings after Cade Smith blew the save in the ninth, winning 6-5 thanks to rookie sensation Chase DeLauter's fourth home run of the season.
Cleveland will try to take three of four, which would be an impressive way to start the year, since it's a road series against a World Series contender.
Right-hander Slade Cecconi is on the mound for the Guardians. He struggled last season with a 5.00 xERA, but he's looked sharp this spring, including four scoreless innings against the Diamondbacks in his final tune-up.
With Cecconi's underwhelming stuff (93 Stuff+) and lack of strikeout ability (20.0 K%), he could have a tough time against a Mariners lineup that is stacked with power hitters like Julio Rodriguez and Cal Raleigh.
Seattle Mariners Betting Preview
The Mariners will look to salvage the split in this four-game series against the Guardians. It's been disappointing because both losses were by two runs or fewer.
The M's need their superstar Cal Raleigh to get on track, as he's 1-for-8 with nine strikeouts so far. Perhaps in facing a righty who pitches to contact in Cecconi, Big Dumper can find his groove.
Like Cleveland, Seattle is sending out a pitcher who struggled last year in Emerson Hancock. This is a righty who gave up a 5.52 xERA and struggled to rack up strikeouts (16.6 K%).
That's bad news against the red-hot Guardians bats like DeLauter, not to mention perennial All-Star Jose Ramirez.
It also doesn't help that Hancock struggled in his last spring outing, giving up three runs on eight hits in 3.2 innings against the Brewers.
Guardians vs Mariners Pick, Betting Analysis
Both Cecconi and Hancock are unlikely to go more than five innings in this game. That's partly because it's their season debuts, but also because they're backend starters.
Then you have to consider that these teams just played an extra-inning game.
High-leverage relievers like Cade Smith (28 pitches) and Andres Muñoz (20 pitches) had heavy workloads, so they may be unavailable for this one.
I know that T-Mobile Park is one of the most pitcher-friendly environments in baseball, but 7.5 runs feels too low considering the probable starters and the taxed bullpens. For context, this number was 7.5 with an ace like Bryan Woo on the mound last night.
Feels like this should be listed at 8.5. With that in mind, we'll take a shot on the over here.
Pick: Guardians/Mariners Over 7.5 (-112, DraftKings)
