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Astros vs Tigers Prediction, Pick, MLB Odds for Sunday, June 28

Astros vs Tigers Prediction, Pick, MLB Odds for Sunday, June 28 article feature image
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Jun 22, 2026; Toronto, Ontario, CAN; Houston Astros starting pitcher Hunter Brown (58) looks in at home plate before throwing a pitch against the Toronto Blue Jays during the first inning at Rogers Centre. Mandatory Credit: Nick Turchiaro-Imagn Images

The Detroit Tigers host the Houston Astros on June 28, 2026. First pitch from Comerica Park is scheduled for 1:40 p.m. EDT. The game will be broadcast on DSN.

The Astros are favored by -124 on the moneyline and by -1.5 on the run line. The Tigers are +106 on the moneyline and +1.5 on the run line. The total is set at 8 runs.

Find my MLB picks and Astros vs Tigers prediction below, as well as probable pitchers, weather report, and more.


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Astros vs Tigers Prediction

  • Astros vs Tigers Pick: Astros F5 ML

Astros vs Tigers Odds

Astros Logo
Sunday, Jun 28
1:40 p.m. ET
DSN
Tigers Logo
Astros Odds
SpreadTotalMoneyline
-1.5
+138
8
-114o / -106u
-124
Tigers Odds
SpreadTotalMoneyline
+1.5
-170
8
-114o / -106u
+106
Odds via FanDuel. Get up-to-the-minute MLB odds here.
FanDuel Logo


Astros vs Tigers Probable Pitchers

Hunter Brown (RHP, HOU)StatJack Flaherty (RHP, DET)
1-0W-L1-8
0.6fWAR (FanGraphs)1.0
1.40 / 2.46ERA / xERA5.35 / 4.65
2.90 / 3.08FIP / xFIP4.10 / 4.56
21.0%K-BB%14.4%
57.5%GB%30.3%
.282BABIP.337
104Stuff+100
97Location+95

Astros vs Tigers MLB Betting Preview

The Tigers will host the Astros on Sunday in the last of a three-game set at Comerica Park in Detroit.

I’m excited for this pitching matchup between Hunter Brown and Jack Flaherty

Brown has only made four starts this season after dealing with injuries, but he’s been nothing but exceptional, having allowed just three earned runs across his first 19 frames with 28 strikeouts.

Unfortunately, Flaherty has seemingly fallen off. He's struggling with command (11% walk rate), his stuff is declining (5.14 botERA, career-low 92.9 MPH average fastball velocity), and he's running an ERA in the mid-fives.


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Astros vs Tigers Pick, Betting Analysis

Houston has a massive starting pitching advantage in this one, and Houston's lineup is still very dangerous.

I'll happily take a shot with the Astros on the F5 ML, especially against a slumping Tigers squad that has severely underperformed this season.

Pick: Astros F5 ML


Astros vs Tigers Weather


Get the latest coverage on MLB Weather.
Author Profile
About the Author

Ryan graduated from Providence College in 2016 with Bachelor Degrees in Business Economics & Mathematics. It was at Providence where Ryan really first found his passion for sports betting. For a lifelong sports fan with a knack for statistical analysis, he was instantly drawn to the fundamentals of the industry, specifically how sports betting markets functioned and fluctuated. In what primarily started as a recreational hobby, Ryan began studying the ins-and-outs of sports betting markets on a daily basis. He took to Twitter (now X), where he amassed a following for writing a sports betting blog that provided statistical analysis behind his wagers. In spite of seeking employment opportunities elsewhere post graduation, Ryan continued to follow his passion for the statistical analysis of sports betting wagers, eventually deciding to pursue a career in the sports betting industry.

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