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Angels vs Mariners Prediction, Pick, MLB Odds for Saturday, September 26

Angels vs Mariners Prediction, Pick, MLB Odds for Saturday, September 26 article feature image
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IMAGN IMAGES via Reuters Connect. Pictured: Ryan Johnson

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The Seattle Mariners host the Los Angeles Angels on September 26, 2026. First pitch from T-Mobile Park is scheduled for 9:40 p.m. EDT. The game will be broadcast on ABTV.

The Mariners are favored by -195 on the moneyline and by -1.5 on the run line. The Angels are +162 on the moneyline and +1.5 on the run line. The total is set at 7.5 runs.

Find my MLB picks and Angels vs Mariners prediction below, as well as probable pitchers, weather report, and more.


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Angels vs Mariners Prediction

  • Angels vs Mariners Pick: R.Johnson Over 4.5 Strikeouts (+114, 0.5u, Bet to +100)

My Angels vs Mariners best bet is Ryan Johnson to go over his strikeouts total. Make sure to find the best odds by checking our live MLB odds page.


Angels vs Mariners Odds

Angels Logo
September 26, 2026
9:40 p.m. EDT
ABTV
Mariners Logo
Angels Odds
SpreadTotalMoneyline
+1.5
+113
7.5
-115o / -105u
+162
Mariners Odds
SpreadTotalMoneyline
-1.5
-135
7.5
-115o / -105u
-195
Odds via bet365. Get up-to-the-minute MLB odds here.
bet365 Logo
  • Angels vs Mariners moneyline: Angels +162, Mariners -195
  • Angels vs Mariners over/under: 7.5 (-115o / -105u)
  • Angels vs Mariners spread: Mariners -1.5 (+113 ), Angels +1.5 (-135)

Angels vs Mariners Probable Pitchers

Ryan Johnson (RHP, LAA)StatKade Anderson (LHP, SEA)
5-9W-L2-2
0.0fWAR (FanGraphs)0.5
4.93/4.89ERA / xERA4.18/4.00
5.38/5.11FIP / xFIP3.72/3.79
9.0%K-BB%15.3%
34.1%GB%38.3%
.262BABIP.297
94Stuff+97
94Location+105

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Angels vs Mariners Pick, Betting Analysis

Ryan Johnson has struck out 24 of his last 94 batters with just three walks and a 12.6 SwStr%. He’s had at least five strikeouts in all four starts.

Johnson is a bit of an oddball in that a cutter is his main fastball (43.2% last four, 38% season), and though it’s not usually a bat-missing piece, he’s complementing it with a slider (34%, 23%).

You would think this might lead to a large strikeout split, but on the season, he’s between 18-19% against batters from either side of the plate.

No, that’s not very much, but of the 22 batters I project him to face (at least that many in four straight). The first 22 batters in the projected Seattle lineup average a 24.1 K% vs RHP.

We’re already in a situation where we should probably expect Johnson to improve on his season strikeout rates without even getting to the environment.

The combination of left and right-handed batters Johnson is expected to face would mean an average 15% park strikeout boost. We can also tack on an additional 5% for scheduled umpire Jansen Visconti. Weather shouldn’t impact strikeouts much more than that, but we’re looking at around a 20% environmental boost for Johnson here.

In the end, I’m boosting Johnson’s expected strikeout rate to nearly 25% for this matchup, which I don’t consider exceptional considering the opposing lineup, his last four starts and the environmental effects.

That puts me closer to 5.5 than 4.5, and we’re getting the positive end of the money here (+114 FanDuel).

Picks: R.Johnson Over 4.5 Strikeouts (+114, 0.5u, Bet to +100)


Angels vs Mariners Weather


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About the Author
Matt Trollo • Verified Action Expert

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