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The New York Yankees host the Baltimore Orioles on September 25, 2026. First pitch from Yankee Stadium is scheduled for 7:05 p.m. EDT. The game will be broadcast on MASN.
The Yankees are favored by -130 on the moneyline and by -1.5 on the run line. The Orioles are +110 on the moneyline and +1.5 on the run line. The total is set at 6.5 runs.
Find my MLB picks and Orioles vs Yankees prediction below, as well as probable pitchers, weather report, and more.
Orioles vs Yankees Prediction
- Orioles vs Yankees Pick: Ben Rice Over 0.5 Home Runs (+520)
My Orioles vs Yankees best bet is on Rice to record 1+ home runs. Make sure to find the best odds by checking our live MLB odds page and be sure to download the Action Network app for more picks and analysis.
Orioles vs Yankees Odds
| Orioles Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 +179 | 6.5 -116o / -100u | +110 |
| Yankees Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 -219 | 6.5 -116o / -100u | -130 |
- Orioles vs Yankees moneyline: Orioles +110, Yankees -130
- Orioles vs Yankees over/under: 6.5 (-116o / -100u)
- Orioles vs Yankees spread: Yankees -1.5 (+179 ), Orioles +1.5 (-219)
Orioles vs Yankees Probable Pitchers
| Brandon Young | Stat | TBD |
|---|---|---|
| 9-5 | W-L | |
| 1.4 | fWAR (FanGraphs) | |
| 3.62 / 4.31 | ERA / xERA | |
| 4.53 / 4.46 | FIP / xFIP | |
| 10.6 | K-BB% | |
| 42.6 | GB% | |
| .287 | BABIP | |
| 97 | Stuff+ | |
| 105 | Location+ |
Orioles vs Yankees MLB Betting Preview
Orioles vs Yankees Pick, Betting Analysis
This is a plus spot, and these odds are far too high. Brandon Young has been a plus matchup for lefty power this season, allowing a 1.35 HR/9. The weather does have heavy wind crossing from left to right, which will have a neutral effect on lefty power (at worst). This ballpark is one of the best in the league for lefty power, and Ben Rice is one of the best HR hitters in the league. I have the true odds here around +400.
Pick: Ben Rice Over 0.5 Home Runs (+520)
