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The Athletics host the Houston Astros on September 25, 2026. First pitch from Sutter Health Park is scheduled for 9:40 p.m. ET. The game will be broadcast on SCHN.
The Astros are favored by -172 on the moneyline and by -1.5 on the run line. The Athletics are +144 on the moneyline and +1.5 on the run line. The total is set at 9.5 runs.
Find my MLB picks and Astros vs. Athletics prediction below, as well as probable pitchers, weather report, and more.
Astros vs Athletics Prediction
- Astros vs Athletics Picks: Shea Langeliers HR (+470), Lawrence Butler HR (+750), Zack Gelof HR (+680), Yordan Alvarez HR (+260)
My Astros vs Athletics best bets are homers for three A's players and the Astros slugger. Make sure to find the best odds by checking our live MLB odds page, and download the Action Network app for more picks and analysis.
Astros vs Athletics Odds
| Astros Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 -108 | 9.5 104o / -128u | -172 |
| Athletics Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -111 | 9.5 104o / -128u | +144 |
- Astros vs Athletics moneyline: Astros -172, Athletics +144
- Astros vs Athletics over/under: 9.5 (+104o / -128u)
- Astros vs Athletics spread: Astros -1.5 (-108), Athletics +1.5 (-111)
Astros vs Athletics Probable Pitchers
| Hunter Brown (RHP, HOU) | Stat | Jacob Lopez (LHP, ATH) |
|---|---|---|
| 6-3 | W-L | 6-5 |
| 1.8 | fWAR (FanGraphs) | 0.8 |
| 3.26 / 3.24 | ERA / xERA | 5.68 / 3.65 |
| 3.76 / 3.47 | FIP / xFIP | 5.23 / 5.19 |
| 16.2 | K-BB% | 9.8 |
| 56.8 | GB% | 31.0 |
| .282 | BABIP | .301 |
| 104 | Stuff+ | 98 |
| 96 | Location+ | 103 |
Astros vs Athletics MLB Betting Preview, Predictions
By Derek Carty
Editor's Note: These written picks are a transcription from today's episode of the Payoff Pitch Podcast.
I am looking at three A's to hit home runs today. We have Shea Langeliers (+470, good down to +355), Lawrence Butler (+750, I like it down to +670), and then Zach Gelof (+680, and I like it down to +590).
They're facing Astros ace Hunter Brown, but The Bat X has always thought he's a little overrated. His stuff isn't anything overwhelming.
Brown's control this year hasn't been great, and more than anything else, it's the environment here. We're coming towards the end of the year; everywhere is getting cold. But Sacramento isn't cold. It's an elite hitter's park to begin with, and almost 90 degrees there, with double-digit winds blowing out.
It just feels like the books still aren't properly accounting for this summer weather still going on in Sacramento.
I would also add Yordan Alvarez (+260, down to +250). I shouldn't need to sell you on this one too much, as obviously Alvarez is really good at hitting homers.
Picks: Shea Langeliers HR (+470), Lawrence Butler HR (+750), Zack Gelof HR (+680), Yordan Alvarez HR (+260)
