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MLB Odds: 2 Yankees vs Giants Prop Picks, +1350 Parlay Tonight

MLB Odds: 2 Yankees vs Giants Prop Picks, +1350 Parlay Tonight article feature image
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A view of a New York Yankees helmet and logo. Credit: Jerome Miron-Imagn Images

A strikeout prop and home run pick both stick out for Yankees vs. Giants using PRO.

Wednesday's the start of the MLB season!

Yankees vs. Giants (8:05 p.m. ET, Netflix) takes center stage. Despite a one-game slate, PRO tools identified plenty of smart ways to attack the regular-season opener.

Wednesday's MLB odds for Yankees vs. Giants pit New York as a -120 road favorite. The over/under at Oracle Park, meanwhile, is 7 runs.

Here are a couple of data-driven MLB selections and a +1350 parlay for Thursday using PRO data when Max Fried and Logan Webb duel in the 2026 MLB opener.

MLB Odds: 2 Yankees vs Giants Picks, +1350 Parlay Tonight

A quick rundown of what to expect from MLB PRO this season:

  • Public betting percentages
  • Projections for home runs, strikeouts, hits and other props
  • Full PRO Report (sharp-action signals, real-time expert picks, etc.)

And plenty more.

With the PRO Report a bit quiet today, the two best picks to lock in for Yankees vs. Giants using PRO tools are props.

First, Max Fried