HomeRight ArrowMLB

Rockies vs White Sox Prediction, Pick, MLB Odds for Friday, September 25

Rockies vs White Sox Prediction, Pick, MLB Odds for Friday, September 25 article feature image
2 min read
Credit:

Pictured: Chicago White Sox pitcher Sean Burke. (Credit: Patrick Gorski-Imagn Images)

If you want more Action Network content, be sure to add us as a preferred source on Google.

The Chicago White Sox host the Colorado Rockies on September 25, 2026. First pitch from Rate Field is scheduled for 7:40 p.m. EDT. The game will be broadcast on CHSN.

The White Sox are favored by -252 on the moneyline and by -1.5 on the run line. The Rockies are +204 on the moneyline and +1.5 on the run line. The total is set at 8 runs.

Find my MLB picks and Rockies vs White Sox prediction below, as well as probable pitchers, weather report, and more.


Header First Logo
Header Second Logo

Rockies vs White Sox Prediction

  • Rockies vs White Sox Pick: Sean Burke Over 1.5 Walks Allowed (+170; Play to +115)

My Rockies vs White Sox best bet is on Sean Burke to go over 1.5 walks allowed. Make sure to find the best odds by checking our live MLB odds page and download the Action Network app for more picks and analysis.


Rockies vs White Sox Odds

Rockies Logo
Friday, Sep 25
7:40 p.m. ET
CHSN
White Sox Logo
Rockies Odds
SpreadTotalMoneyline
+1.5
-106
8
-107o / -113u
+204
White Sox Odds
SpreadTotalMoneyline
-1.5
-114
8
-107o / -113u
-252
Odds via DraftKings. Get up-to-the-minute MLB odds here.
DraftKings Logo
  • Rockies vs White Sox moneyline: Rockies +204, White Sox -252
  • Rockies vs White Sox over/under: 8 (-107o / -113u)
  • Rockies vs White Sox spread: White Sox -1.5 (-114), Rockies +1.5 (-106)

Rockies vs White Sox Probable Pitchers

Tomoyuki Sugano (RHP, COL)StatSean Burke (RHP, CHW)
12-11W-L10-7
0.4fWAR (FanGraphs)3.1
5.36/6.48ERA / xERA3.40/3.85
5.38/4.75FIP / xFIP3.62/4.01
8.7%K-BB%16.8%
37.6%GB%35.1%
.277BABIP.284
82Stuff+99
103Location+100

Rockies vs White Sox MLB Betting Preview

By Derek Carty

Editor's Note: This written best bet is a transcription from the latest episode of the Payoff Pitch podcast.

I'm looking at Sean Burke over 1.5 walks allowed for this game (+170 on DraftKings, play down to +115). It's a huge price for something that projects as a virtual coin flip—I have this projected at a 51% win rate, making +170 strong value.

While the Rockies are a low-walk team and the matchup isn't ideal on paper, Burke has struggled with his control this season.

You could play the narrative game and argue there might be a hangover effect after securing a postseason spot, but Chicago is still playing for the AL Central division title. Because of that, I don't expect him to be on a short leash like you often see in rest spots. Burke should get a full workload, making +170 a great number.

Pick: Sean Burke Over 1.5 Walks Allowed (+170; Play to +115)


Rockies vs White Sox Weather


Get the latest coverage on MLB Weather.
Author Profile
About the Author

Action Network is a team of seasoned sports betting experts specializing in a broad range of sports, from the NFL and NBA to less mainstream options like cricket and darts. Their staff includes well-known analysts like Sean Koerner and Stuckey, recognized for their accurate predictions and deep sports knowledge. The team is dedicated to delivering expert analysis and daily best bets, ensuring bettors are well-informed across all major sports.

This site contains commercial content. We may be compensated for the links provided on this page. The content on this page is for informational purposes only. Action Network makes no representation or warranty as to the accuracy of the information given or the outcome of any game or event.