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Mets vs Nationals Prediction, Odds: 3 Expert MLB Prop Picks for Wednesday, May 20

Mets vs Nationals Prediction, Odds: 3 Expert MLB Prop Picks for Wednesday, May 20 article feature image
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May 19, 2026; Washington, District of Columbia, USA; Washington Nationals shortstop CJ Abrams (5) stands on second base after being thrown out while attempting to steal the base against the New York Mets during the sixth inning at Nationals Park. Mandatory Credit: Rafael Suanes-Imagn Images

The Washington Nationals host the New York Mets on May 20, 2026. First pitch from Nationals Park is scheduled for 6:45 p.m. EDT. The game will be broadcast on SNY.

The Mets are favored by -126 on the moneyline and by -1.5 on the run line. The Nationals are +108 on the moneyline and +1.5 on the run line. The total is set at 9.5 runs.

Find my MLB picks and Mets vs Nationals prediction below, as well as probable pitchers, weather report, and more.


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Mets vs Nationals Prediction

Mets vs Nationals Picks, Props:

  • Bo Bichette Over 1.5 HRR (-220)
  • CJ Abrams Over 1.5 TB (+115)
  • CJ Abrams Home Run (+610)

Mets vs Nationals Odds

Mets Logo
Wednesday, May 20
6:45 p.m. ET
SNY
Nationals Logo
Mets Odds
SpreadTotalMoneyline
-1.5
+125
9.5
-115o / -105u
-126
Nationals Odds
SpreadTotalMoneyline
+1.5
-150
9.5
-115o / -105u
+108
Odds via FanDuel. Get up-to-the-minute MLB odds here.
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Mets vs Nationals Probable Pitchers

Zach Thornton (LHP, NYM)StatZack Littell (RHP, WSN)
Season DebutW-L2-4
fWAR (FanGraphs)-1.0
ERA / xERA6.10 / 7.73
FIP / xFIP7.71 / 5.76
K-BB%2.7%
GB%37.3%
BABIP.239
Stuff+83
Location+96

Mets vs Nationals MLB Betting Preview

Nationals’ right-hander Zack Littell is set to take the mound for Washington, while the Mets currently don't list a starter for Wednesday following Clay Holmes' recent trip to the IL.

Littell enters Wednesday’s contest with an atrocious 6.10 ERA on the mound over his first nine outings in 2026.

The Nats’ righty is coming off several impressive campaigns in recent years, with Washington’s 30-year-old having finished four of his last six seasons with an ERA below 4.00.

It seems that regression has finally arrived for the Nationals’ right-hander as he prepares to face a Mets lineup that has finally started to find its groove at the plate.


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Mets vs Nationals Pick, Betting Analysis

Littell has actually fared pretty well versus this Mets lineup as a whole, but has struggled mightily pitching against Mets’ utility infielder Bo Bichette, who has thrived in his 14 previous plate appearances versus the Nats’ righty.

The former Bluejay has smashed a double, a home run, and has recorded 3 RBIs across his prior encounters with Littell.

In a game where I expect runners to be consistently on the base paths, I favor targeting Bichette to exceed his 1.5 HRR mark ahead of Wednesday night’s divisional showdown.

While it is not definitive who the Mets will send out to the bump on Wednesday (Editor's Note: It will be Zach Thornton, who will make his season debut), I will still be looking to target Nationals’ youngster CJ Abrams in player prop markets in a game that should deliver many runs.

Nationals’ SS CJ Abrams is scorching to start his 2026 campaign, with the 25-year-old ranking inside the top-15 in baseball in regard to batting average, RBIs, and OPS.

Abrams is mashing at the plate with a .300 AVG, .532 slugging percentage, and also ranking third in the Major Leagues with 39 RBIs thus far.

Though we currently have minimal information about the Mets’ approach to their pitching staff ahead of Wednesday’s matchup, New York’s bullpen is really struggling.

Regardless, I expect Abrams to extend his hot streak at the plate and to further exceed his 1.5 TB mark in this NL East showdown. Also, I will be looking to back CJ to blast one out of the park in what is projected to be ideal ballpark & weather conditions in DC on Wednesday.


Mets vs Nationals Picks, Props

  • Bo Bichette Over 1.5 HRR (-140)
  • CJ Abrams Over 1.5 TB (+110)
  • CJ Abrams Home Run (+570)

Mets vs Nationals Weather


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About the Author

Ryan graduated from Providence College in 2016 with Bachelor Degrees in Business Economics & Mathematics. It was at Providence where Ryan really first found his passion for sports betting. For a lifelong sports fan with a knack for statistical analysis, he was instantly drawn to the fundamentals of the industry, specifically how sports betting markets functioned and fluctuated. In what primarily started as a recreational hobby, Ryan began studying the ins-and-outs of sports betting markets on a daily basis. He took to Twitter (now X), where he amassed a following for writing a sports betting blog that provided statistical analysis behind his wagers. In spite of seeking employment opportunities elsewhere post graduation, Ryan continued to follow his passion for the statistical analysis of sports betting wagers, eventually deciding to pursue a career in the sports betting industry.

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