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Mariners vs White Sox Prediction, Pick, Odds: Wrong Team Favored?

Mariners vs White Sox Prediction, Pick, Odds: Wrong Team Favored? article feature image
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May 8, 2026; Chicago, Illinois, USA; Chicago White Sox first baseman Munetaka Murakami (5) reacts after hitting a solo home run against the Seattle Mariners during the first inning at Rate Field. Mandatory Credit: Kamil Krzaczynski-Imagn Images

The Chicago White Sox host the Seattle Mariners on May 9, 2026. First pitch from Rate Field is scheduled for 7:10 p.m. EDT. The game will be broadcast on SEAM.

The Mariners are favored by -134 on the moneyline and by -1.5 on the run line. The White Sox are +114 on the moneyline and +1.5 on the run line. The total is set at 9.5 runs.

Find my MLB picks and Mariners vs White Sox prediction below, as well as probable pitchers, weather report, and more.


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Mariners vs White Sox Prediction

  • Mariners vs White Sox Pick: White Sox ML (+110 or Better) | White Sox F5 ML (+110 or Better)

My Mariners vs White Sox best bet is on Chicago to win both halves. Make sure to find the best odds by checking our live MLB odds page.


Mariners vs White Sox Odds

Mariners Logo
Saturday, May 9
7:10 p.m. ET
SEAM
White Sox Logo
Mariners Odds
SpreadTotalMoneyline
-1.5
+118
9.5
-105o / -115u
-134
White Sox Odds
SpreadTotalMoneyline
+1.5
-142
9.5
-105o / -115u
+114
Odds via FanDuel. Get up-to-the-minute MLB odds here.
FanDuel Logo
  • Mariners vs White Sox moneyline: Mariners -134, White Sox +114
  • Mariners vs White Sox over/under: 9.5 (-105o / -115u)
  • Mariners vs White Sox spread: Mariners -1.5 (+118), White Sox +1.5 (-142)

Mariners vs White Sox Probable Pitchers

Luis Castillo (RHP, SEA)StatAnthony Kay (LHP, CHW)
0-3W-L1-1
0.4fWAR (FanGraphs)-0.2
6.29 / 5.86ERA / xERA5.70 / 7.62
4.24 / 4.63FIP / xFIP6.40 / 5.65
11.2%K-BB%3.5%
33.0%GB%39.2%
.367BABIP.299
98Stuff+103
111Location+101

Mariners vs White Sox MLB Betting Preview

To be clear from the start, I’m not trying to convince you Anthony Kay has been anybody’s idea of a good pitcher in his return to the league this year (5.28 SIERA, 7.60 xERA). In fact, he’s been even worse than his opponent, Luis Castillo (4.44, 5.84).

However, what do we always look for in Luis Castillo starts?

Is he at home? No

Is he facing a predominantly left-handed lineup? Seven projected.

LHBs vs Luis Castillo on the road:

  • Career: .350 wOBA
  • 2026: .364 wOBA
  • 2025: .405 wOBA

The difference is that RHBs are above a .400 wOBA against Castillo too away from Seattle this year.

Castillo was averaging 97.1 mph on his fastball as recently as 2022, but is now down to 94.9 mph.


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Mariners vs White Sox Pick, Betting Analysis

Here are some additional comparisons:

  • Team Home/Road wRC+ 2026: White Sox 86/Mariners 81
  • Team vs RHP 2026: White Sox 92/Mariners 82
  • Projected LU vs RHP since 2025: White Sox 122/Mariners 111
  • Projected LU wRC+ L30 days overall: White Sox 128/Mariners 112

There are certainly some sample size issues in the above numbers, but there is some smoke.

The projected Chicago (AL) defense also has a 17 Fielding Run Value edge over Seattle, and that's not a sample size blip.

I’m not sure the White Sox should even be dogs here.

I'm splitting a unit between F5 and the full game.

Pick: White Sox ML (+110 or Better) | White Sox F5 ML (+110 or Better)


Mariners vs White Sox Weather


Get the latest coverage on MLB Weather.
Author Profile
About the Author
Matt TrolloVerified Action Expert

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