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Cardinals vs Reds Prediction, Pick, MLB Odds for Wednesday, August 19

Cardinals vs Reds Prediction, Pick, MLB Odds for Wednesday, August 19 article feature image
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Pictured: Cincinnati Reds starting pitcher Chase Burns. (Credit: Katie Stratman-Imagn Images)

The Cincinnati Reds host the St. Louis Cardinals on August 19, 2026. First pitch from Great American Ball Park is scheduled for 6:40 p.m. EDT. The game will be broadcast on CARD.

The Reds are favored by -138 on the moneyline and by -1.5 on the run line. The Cardinals are +128 on the moneyline and +1.5 on the run line. The total is set at 8.5 runs.

Find my MLB picks and Cardinals vs Reds prediction below, as well as probable pitchers, weather report, and more.


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Cardinals vs Reds Prediction

  • Cardinals vs Reds Pick: Reds F5 ML

My Cardinals vs Reds best bet is on the Reds moneyline after the first five innings. Make sure to find the best odds by checking our live MLB odds page.


Cardinals vs Reds Odds

Cardinals Logo
Wednesday, Aug 19
6:40 p.m. ET
CARD
Reds Logo
Cardinals Odds
SpreadTotalMoneyline
+1.5
-176
8.5
-106o / -114u
+128
Reds Odds
SpreadTotalMoneyline
-1.5
+146
8.5
-106o / -114u
-138
Odds via FanDuel. Get up-to-the-minute MLB odds here.
FanDuel Logo
  • Cardinals vs Reds moneyline: Cardinals +128, Reds -138
  • Cardinals vs Reds over/under: 8.5 (-106o / -114u)
  • Cardinals vs Reds spread: Reds -1.5 (+146), Cardinals +1.5 (-176)

Cardinals vs Reds Probable Pitchers

Matthew Liberatore (LHP, STL)StatChase Burns (RHP, CIN)
5-10W-L14-2
0.9fWAR (FanGraphs)3.9
5.07/4.84ERA / xERA2.47/3.04
4.55/4.17FIP / xFIP3.14/3.50
13.9%K-BB%20.0%
37.3%GB%36.6%
.335BABIP.267
98Stuff+112
100Location+102

Cardinals vs Reds MLB Betting Preview, Prediction

The Reds host the Cardinals on Wednesday. Chase Burns will start for Cincinnati, while Matthew Liberatore will start for St. Louis.

Suffice it to say, the Reds have a big starting pitching advantage in this game.

Across 23 starts this season, Burns is 14-2 with a 2.47 ERA and 1.06 WHIP — he’s also recorded a whopping 151 strikeouts. The former No. 2 overall pick is starting to live up to the hype.

Meanwhile, Liberatore has struggled, pitching to a 5.07 ERA and 1.48 WHIP across 24 starts this year.

I think the Reds easily jump out to an early lead.

Pick: Reds F5 ML


Cardinals vs Reds Weather


Get the latest coverage on MLB Weather.


Author Profile
About the Author

Ryan graduated from Providence College in 2016 with Bachelor Degrees in Business Economics & Mathematics. It was at Providence where Ryan really first found his passion for sports betting. For a lifelong sports fan with a knack for statistical analysis, he was instantly drawn to the fundamentals of the industry, specifically how sports betting markets functioned and fluctuated. In what primarily started as a recreational hobby, Ryan began studying the ins-and-outs of sports betting markets on a daily basis. He took to Twitter (now X), where he amassed a following for writing a sports betting blog that provided statistical analysis behind his wagers. In spite of seeking employment opportunities elsewhere post graduation, Ryan continued to follow his passion for the statistical analysis of sports betting wagers, eventually deciding to pursue a career in the sports betting industry.

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