The Cincinnati Reds host the St. Louis Cardinals on May 24, 2026. First pitch from Great American Ball Park is scheduled for 1:40 p.m. EDT. The game will be broadcast on CARD.
The Reds are -116 on the moneyline. The Cardinals are -102 on the moneyline. The total is set at 9.5 runs.
Find my MLB picks and Cardinals vs Reds prediction below, as well as probable pitchers, weather report, and more.
Cardinals vs Reds Prediction
Cardinals vs Reds Picks:
- Sal Stewart Over 1.5 Total Bases
- Sal Stewart Over 0.5 Home Runs
Cardinals vs Reds Odds
| Cardinals Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +158 | 9.5 -105o / -115u | -102 |
| Reds Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -192 | 9.5 -105o / -115u | -116 |
Cardinals vs Reds Probable Pitchers
| Matthew Liberatore (LHP, STL) | Stat | Brady Singer (RHP, CIN) |
|---|---|---|
| 2-2 | W-L | 2-4 |
| 0.1 | fWAR (FanGraphs) | -0.4 |
| 4.70 / 5.65 | ERA / xERA | 6.26 / 6.07 |
| 4.86 / 4.27 | FIP / xFIP | 6.55 / 4.48 |
| 10.2% | K-BB% | 10.2% |
| 37.7% | GB% | 39.8% |
| .331 | BABIP | .340 |
| 98 | Stuff+ | 91 |
| 101 | Location+ | 99 |
Cardinals vs Reds MLB Betting Preview
National League Central foes collide on Sunday afternoon as the Reds prepare to host the Cardinals at the Great American Ballpark in Cincinnati.
Cardinals’ lefty Matthew Liberatore looks to bounce back from a rough start to his 2026 campaign, having recorded a 4.70 ERA thus far across his nine appearances this season.
In a matchup featuring two struggling pitchers, I expect both lineups to deliver an offensive explosion on Sunday afternoon, so I will be targeting player prop markets as my betting angle for this contest.
While in just his second season in the Big Leagues after suiting up for 18 games in 2025, the Reds’ 22-year-old top prospect at first base, Sal Stewart, has already made his mark as one of the best young sluggers in baseball.
The Reds’ righty is mashing at the plate, having driven in 34 runs (RBIs) and ripped 12 homers over Cincy’s first 50 games of the season.
Coincidentally, one of Stewart’s 12 bombs actually came off Liberatore, which is why I will be looking to go “back to the well” targeting the Reds youngster in prop markets ahead of Sunday’s ball game.
The Reds’ top prospect has already established an edge over the Cardinals’ left-hander, and I could definitely see Stewart building upon his prior success versus Liberatore with another monster performance.
That said, I will be looking to back Stewart both to exceed his 1.5 HRR mark on Sunday and also to smash his 13th homer of the year — and his second off of the Cardinals’ lefty.
Picks:
- Sal Stewart Over 1.5 Total Bases
- Sal Stewart Over 0.5 Home Runs
