Cavaliers vs 76ers Odds & Live Scores - October 22, 2026

Cavaliers at 76ers

11:00 pm • ESPN

Cleveland Cavaliers

Philadelphia 76ers

MatchupOpenSpreadTotalMoneyline
Cavaliers 0-0	+4.5	+3.5-115	o235.5-110	+125
76ers 1-0	u233.5	-3.5-105	u235.5-108	-150

Thursday 11:00 p.m.

October 22, 2026

Xfinity Mobile ArenaPhiladelphia

J.Allen o21.5 Pts+Rebs-112

0.55u

CLE +3.5-110

0.55u

CLE +125

0.1u

V.Edgecombe o10.5 Pts-108

0.55u

D.Mitchell u25.5 Pts+105

0.48u

K.Caldwell-Pope u6.5 Pts-112

0.56u

V.Edgecombe u4.5 Rebs+110

0.45u

T.Maxey o5.5 Ast+107

0.47u

E.Mobley o1.5 3pt M+195

0.26u

V.Edgecombe u1.5 3pt M-125

0.63u

J.Allen o21.5 Pts+Rebs+134

0.5u

D.Mitchell u4.5 Ast+110

0.5u

J.Allen o21.5 Pts+Rebs-105

0.55u

D.Mitchell u4.5 Ast+110

0.4u

J.Harden u2.5 3pt M+110

0.91u

K.Caldwell-Pope u1.5 3pt M-165

1.65u

V.Edgecombe o7.5 Rebs+Ast+102

E.Mobley u27.5 Pts+Rebs-120

1.2u

J.Brown o19.5 Pts-124

1.24u

D.Mitchell u2.5 3pt M+130

0.77u

PHI -2.5-110

1.1u

E.Mobley o17.5 Pts-104

1.04u

PHI -2.5-105

@BKPicks ⭐️⭐️⭐️ https://www.youtube.com/live/X2D5P9ZV4Yc?is=lISaF5pJn7XqmWcM

J.Embiid o7.5 Rebs-135

0.5u

@BKPicks ⭐️⭐️ https://www.youtube.com/live/X2D5P9ZV4Yc?is=lISaF5pJn7XqmWcM

L.James First Basket (incl. FT) Yes+1100

0.25u

@BKPicks ⭐️ https://www.youtube.com/live/X2D5P9ZV4Yc?is=lISaF5pJn7XqmWcM

Cavaliers vs 76ers: Fonseca's Pick for Thursday Night
Bryan Fonseca•
Oct 22, 2026 UTC

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NBA Public Betting

76ers are 1-0 in their last 5 games.
76ers are 1-0 in their last 5 games against the spread
76ers are 1-0 in their road games against the spread
The totals have gone OVER in 0 of 76ers' last 1 games

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
76ers	1-0	N/A	1-0	N/A	1-0
Cavaliers	N/A	N/A	N/A	N/A	N/A

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
76ers	0-1	N/A	0-1	N/A	0-1
Cavaliers	N/A	N/A	N/A	N/A	N/A

Straight-Up (ML) History

	overall	home	away	favorite	underdog
76ers	1-0	N/A	N/A	N/A	1-0
Cavaliers	N/A	N/A	N/A	N/A	N/A

date	opponent	score	spread	over/under	moneyline
Oct 20th	@NYK	W 106-100	+5 W	U 223.5	PHI +148
Oct 16th	BOS	L 120-125	-10.5 L	O 225.5	BOS -450
Oct 11th	@BOS	L 106-144	+8 L	O 225	BOS +220
Oct 8th	@BKN	L 108-114	-8.5 L	O 220.5	BKN -298
Oct 5th	NYK	W 120-97	+4.5 W	U 228.5	PHI +160

Dean Wade
PF
Wade is questionable with ankle
Questionable

Tacko Fall
C
Fall is out with quad
Out
Dominick Barlow
SF
Barlow is out with back
Out
Ariel Hukporti
C
Hukporti is out with achilles
Out

Jarrett Allen
C
Allen is questionable with knee
Questionable
Khalifa Diop
SF
Diop is out with knee
Out
Nae'Qwan Tomlin
PF
Tomlin is out with back
Out

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Cavaliers

76ers

0-0 (NaN%)

Field Goals

37-89 (42%)

0-0 (NaN%)

Free Throws

21-27 (78%)

0-0 (NaN%)

11-40 (28%)

Rebounds

Assists

Turnovers

Steals

Blocks

Fouls

Could not load odds

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MatchupOverUnder
Cavaliers 0-0	N/A	N/A
76ers 1-0	N/A	N/A

Cavaliers vs. 76ers Odds & Betting Predictions - October 22, 2026

Cavaliers at 76ers

Cleveland Cavaliers

Philadelphia 76ers

Cavaliers at 76ers Odds

Spread, Total, Moneyline

Cavaliers vs. 76ers Previews & Analysis

Cavaliers vs 76ers: Fonseca's Pick for Thursday Night

Prop Odds Comparison

Line Movement Tracker

Cavaliers vs. 76ers Public Betting Percentages

Cavaliers

Public

76ers

Bets%

Money%

Betting Trends

Matchup History

Against the Spread (ATS) History

Over/Under History

Straight-Up (ML) History

Last 5 Matchups

76ers vs. Cavaliers Injury Updates

76ers Injuries

Cavaliers Injuries

Cavaliers vs. 76ers Odds Comparison

Cavaliers at 76ers Team Totals