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Notre Dame vs. Louisville Odds & Betting Predictions - February 5, 2026

Notre Dame at Louisville

12:00 am • ESPN2

Notre Dame Fighting Irish

11-13
65
65 - 76

Louisville Cardinals

18-6
76

Notre Dame at Louisville Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Notre Dame
11-13
+14.5
+18.5-112
o155.5-112
+1100
Louisville
18-6
u152.5
-18.5-110
u155.5-110
-2500
location pinThursday 12:00 a.m.
February 05, 2026
KFC Yum! CenterLouisville
Notre Dame vs. Louisville Expert Picks
Mjaybrod
Mjaybrod
Last 30d: 58-49-0 (+17.9u)
R.Conwell o19.5 Pts-110
0.75u
1/11 from 3 last game
Ryan Minion
Ryan Minion
Last 30d: 222-232-4 (+54.1u)
M.Brown o4.5 Ast-130
$1.00
LOU -9 (1H)-120
$1.20
Mike McNamara
Mike McNamara
Last 30d: 62-85-1 (-3.6u)
ND +17.5-114
0.2u
Full Preview on Action Network.

Notre Dame vs. Louisville Previews & Analysis

  • Notre Dame vs Louisville: Who Will Cover the Spread? article feature image

    Notre Dame vs Louisville: Who Will Cover the Spread?

    Mike McNamara•
    Feb 4, 2026 UTC
  • The College Basketball Picks You NEED To Tail! | Big Bets On Campus article feature image

    The College Basketball Picks You NEED To Tail! | Big Bets On Campus

    •
    Feb 2, 2026 UTC
See more NCAAB Coverage Right Arrow

Prop Odds Comparison

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Line Movement Tracker

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Notre Dame vs. Louisville Public Betting Percentages

Away Logo

Notre Dame

Public

Home Logo

Louisville

43%

Bets%

57%

Money%

NCAAB Public Betting Right Arrow

Betting Trends

  • Louisville are 4-1 in their last 5 games.
  • Louisville are 2-3 in their last 5 games against the spread
  • Louisville are 4-5 in their road games against the spread
  • The totals have gone OVER in 2 of Louisville' last 5 games
  • The totals have gone OVER in 5 of Louisville' 15 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Louisville		12-128-74-59-70-3
Notre Dame		12-126-86-44-67-6

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Louisville		9-155-104-57-90-3
Notre Dame		14-109-55-55-58-5

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Louisville		18-6N/AN/A13-30-3
Notre Dame		11-13N/AN/A8-22-11

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Jan 31stSMUW 88-74-9.5 WU 163.5LOU -562
Jan 27th@DUKEL 52-83---
Jan 24thVTW 85-71-14.5 LU 160.5LOU -1225
Jan 18th@PITTW 100-59-7.5 WO 152.5LOU -320
Jan 14thUVAL 70-79-4.5 LU 154.5UVA -214

Notre Dame vs. Louisville Injury Updates

Notre Dame Injuries

  • Markus Burton
    G

    Burton is out with foot

    Out

  • Tommy Ahneman
    C

    Ahneman is out with knee

    Out

Louisville Injuries

    See more NCAAB Injuries Right Arrow
    Team Stats

    24-62 (39%)
    Field Goals
    28-65 (43%)
    6-14 (43%)
    Free Throws
    13-18 (72%)
    11-27 (41%)
    3P
    7-31 (23%)
    33
    Rebounds
    44
    14
    Assists
    19
    11
    Turnovers
    12
    9
    Steals
    6
    3
    Blocks
    4
    17
    Fouls
    16

    Notre Dame vs. Louisville Odds Comparison

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    Notre Dame at Louisville Team Totals

    MatchupOverUnder
    Notre Dame
    11-13
    N/A
    N/A
    Louisville
    18-6
    N/A
    N/A