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Louisville vs. Duke Odds & Betting Predictions - January 27, 2026

Louisville at Duke

12:00 am • ESPN

Louisville Cardinals

0-0
52
52 - 83

Duke Blue Devils

0-0
83

Louisville at Duke Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Louisville
0-0
N/A
N/A
N/A
Duke
0-0
N/A
N/A
N/A
location pinTuesday 12:00 a.m.
January 27, 2026
Cameron Indoor StadiumDurham
Louisville vs. Duke Expert Picks
Stuck 🚨
Stuck 🚨
Last 30d: 61-67-2 (-0.5u)
LOU +7.5-110
0.3u
Mike McNamara
Mike McNamara
Last 30d: 70-68-2 (+0.5u)
LOU +8.5-112
0.28u
Kody Malstrom
Kody Malstrom
Last 30d: 64-45-1 (+6.7u)
Under 157.5-108
0.5u
Doug Ziefel
Doug Ziefel
Last 30d: 362-382-7 (+19.1u)
LOU +8.5-110
0.55u
M.Brown o14.5 Pts-125
0.63u
C.Boozer o9.5 Rebs-125
0.5u
Ryan Minion
Ryan Minion
Last 30d: 226-230-2 (+4.2u)
LOU +7-120
$1.20
ACTION ✍️
LOU +225
$1.00
ACTION ✍️
LOU +7.5-110
$1.10
Action ✍️ (ADD 1u) Mikel SZN!!
LOU +340
$0.20
0.2u (# stab)
M.Brown o14.5 Pts-125
$1.25
LOU +8.5-110
$1.10
ADD 0.5u (# Play)
OldSchool0909
Last 30d: 39-47-1 (-4.0u)
LOU +8.5-105
1u
Mike Calabrese
Mike Calabrese
Last 30d: 37-52-0 (+0.3u)
LOU +7.5-110
1.1u
I wanted to target game two of Mikel Brown’s return
Mjaybrod
Mjaybrod
Last 30d: 50-78-1 (-29.3u)
DUKE -8.5-105
0.95u
Fading the popular dog
Three Man Weave
Three Man Weave
Last 30d: 0-0-0 (+0.0u)
DUKE -7.5-105
1u
💰🦡 Jake
💰🦡 Jake
Last 30d: 84-94-1 (+18.2u)
DUKE -7.5-110
1u
Scott Rickenbach
Scott Rickenbach
Last 30d: 87-91-4 (-13.8u)
LOU +8.5-105
1u
New Owner
New Owner
Last 30d: 0-0-0 (+0.0u)
LOU +6.5-110
$110.00
LOU +8.5-110
$55.00
Babs .
Babs .
Last 30d: 42-35-1 (+0.2u)
LOU +8.5-105
1u
CTO
CTO
Last 30d: 0-0-0 (+0.0u)
LOU +7.5-110
2u

Louisville vs. Duke Previews & Analysis

  • Louisville vs Duke: Back at Full Strength article feature image

    Louisville vs Duke: Back at Full Strength

    Ryan Minion•
    Jan 26, 2026 UTC
  • 3MW's 3 NCAAB Best Bets for Monday article feature image

    3MW's 3 NCAAB Best Bets for Monday

    Matt Cox•
    Jan 26, 2026 UTC
  • How to Bet 2 Ranked NCAAB Big Monday Matchups article feature image

    How to Bet 2 Ranked NCAAB Big Monday Matchups

    Action Network Staff•
    Jan 26, 2026 UTC
See more NCAAB Coverage Right Arrow

Prop Odds Comparison

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Line Movement Tracker

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Louisville vs. Duke Public Betting Percentages

Away Logo

Louisville

Public

Home Logo

Duke

50%

Bets%

50%

Money%

NCAAB Public Betting Right Arrow

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Duke		N/AN/AN/AN/AN/A
Louisville		N/AN/AN/AN/AN/A

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Duke		N/AN/AN/AN/AN/A
Louisville		N/AN/AN/AN/AN/A

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Duke		N/AN/AN/AN/AN/A
Louisville		N/AN/AN/AN/AN/A

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Jan 24thWAKEW 90-69---
Jan 17th@STANW 80-50-11.5 WU 148.5DUKE -750
Jan 15th@CALW 71-56-14.5 WU 149.5DUKE -1233
Jan 10thSMUW 82-75-15.5 LO 156.5DUKE -1465
Jan 7th@LOUW 84-73-1.5 WU 161.5DUKE -112
Team Stats

16-54 (30%)
Field Goals
31-61 (51%)
9-13 (69%)
Free Throws
13-18 (72%)
11-34 (32%)
3P
8-23 (35%)
21
Rebounds
44
11
Assists
14
12
Turnovers
10
6
Steals
7
3
Blocks
1
17
Fouls
12

Louisville vs. Duke Odds Comparison

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Louisville at Duke Team Totals

MatchupOverUnder
Louisville
0-0
N/A
N/A
Duke
0-0
N/A
N/A