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The High Point Panthers take on the Saint Louis Billikens in St. Louis, MO. Tip-off is set for 3 p.m. ET on ESPN2.
Saint Louis is favored by -6.5 points on the spread with a moneyline of -275. The total is set at 164.5 points.
Here’s my High Point vs. Saint Louis prediction and college basketball picks for November 15, 2026.
High Point vs Saint Louis Prediction
Pick: Saint Louis -6.5
My High Point vs Saint Louis best bet is on the Billikens to cover the spread. Be sure to find the best lines by using our live NCAAB odds page and download the Action Network app for the latest picks and analysis.
High Point vs Saint Louis Odds
| High Point Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+6.5 -110 | 164.5 -110o / -110u | +220 |
| Saint Louis Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-6.5 -110 | 164.5 -110o / -110u | -275 |
- High Point vs Saint Louis spread: High Point +6.5 (-110), Saint Louis -6.5 (-110)
- High Point vs Saint Louis over/under: 164.5 (-110o / -110u)
- High Point vs Saint Louis moneyline: High Point +220, Saint Louis -275
High Point vs Saint Louis College Basketball Preview
High Point Basketball
After winning its first NCAA Tournament game in program history last season, High Point has picked up right where it left off, dispatching its first four opponents in impressive fashion.
Despite head coach Flynn Clayman losing most of his offensive production from last season’s 31-5 campaign, the team had quite an offseason, landing 11 new players to overhaul its lineup.
The Panthers have posted a 15-point margin over their first four games, though each win came on their home floor, which will undoubtedly be another factor to consider before this mid-major clash.
Senior forward Cam’Ron Fletcher is off to a great start to his second season under Clayman, leading the team in both scoring and rebounding with 12.8 points per game, along with eight rebounds.
Fletcher’s impact at both ends of the floor will be vital on Sunday, especially considering how poorly High Point has crashed the glass over its first four games, ranking outside the top 200 in rebounding.
He's far and away the best player on this roster and was voted Preseason Big South Player of the Year.
South Florida transfer guard CJ Brown has also started strongly, recording 12.8 points per game over the Panthers’ four victories.
Brown leads an experienced backcourt that also features Jason Rivera-Torres, another acquisition via the transfer portal this past offseason.
These guards lead a High Point portal class that includes six other players. Clayman also recruited three incoming freshmen to help replace its four leading scorers from last season.
While the head coach evidently focused on acquiring long, physical athletes who also excel at crashing the glass, that hasn't been the case so far for High Point, which has struggled to generate second-chance scoring opportunities over its first four games.
Despite how well this new-look lineup has played so far, the Billikens are considerably more talented offensively than all four of the Panthers' previous foes.
Saint Louis Basketball
It's been quite a hectic first two weeks of the season for Saint Louis, which lost out on former star forward Robbie Avila (just acquired by TCU after the court granted him an additional year of collegiate eligibility).
Despite the complications surrounding the Avila saga, the Billikens have looked phenomenal over their first four games, with head coach Josh Schertz and his team averaging a whopping 31-point margin over their first three opponents.
The Billikens are coming off an impressive, hard-fought win over an extremely talented Missouri squad, followed by a remarkable 125-point performance in their latest win over Northern Kentucky.
While Saint Louis has quickly established itself as one of the top mid-major programs in college basketball, the same rings true for a very talented High Point team coming off its first-ever NCAA tournament victory last season.
Schertz returned the likes of Trey Green, Kellen Thames, Quentin Jones, Amari McCottry and Ishan Sharma from last seaon's team, boasting some experience that will be vital to the team’s success as it navigates a tricky non-conference schedule that also features another talented mid-major in Saint Mary's.
Green has been impressive in his second season under Schertz, leading Saint Louis in scoring with 16 points over the team’s first three contests.
The former Xavier guard is lighting it up from 3-point land. He has already knocked down 12 triples at an exceptional 57.1% clip, leading a Billikens squad that ranked third in all of college basketball last season in 3-point field-goal percentage.
Saint Louis boasts some of the best guard play in the country, with all four returning guards averaging more than 13 points per game so far.
McCottry has also been phenomenal at both ends of the floor, scoring 15 points per game with a 77.3% field goal percentage that ranks 13th in college basketball. The 6-foot-6 player is also averaging five rebounds and over three assists.
While Saint Louis has excelled offensively, it has been far less efficient on defense, but can attribute much of that to its offense playing at a very up-tempo pace.
Given how well the Bills played against a Mizzou team with insane athleticism, I expect them to be up to the task here.
High Point vs Saint Louis Pick, Betting Analysis
While Sunday afternoon’s game has all the makings of a closely contested matchup on the surface, with both teams ranked as the top two mid-major programs before the season started, I expect a far more one-sided contest than the betting markets indicate.
Though the Panthers were exceptional last season, with a ton of experience and offensive playmakers, this is a completely different team with glaring holes throughout its rotation that I expect to be exposed by a Billiken squad with legitimate Final Four upside.
I absolutely love the Billikens, and will be backing them to cover both their first-half and full-game spreads in what I expect to be a double-digit point victory.
Picks: Saint Louis -6.5
