The Queens Royals play the Purdue Boilermakers in the first round of the NCAA Tournament from St. Louis, Missouri. Tip-off is set for 7:35 p.m. ET on truTV.
Purdue is favored by -25.5 points on the spread with a moneyline of -10000. Meanwhile, Queens is the underdog at +25.5 with a moneyline of +2500. The total is set at 162.5 points.
Here’s my Queens vs. Purdue predictions and college basketball picks for March 20, 2026.
Queens vs Purdue Prediction
My Pick: Queens +25.5
My Queens vs Purdue best bet is on the Royals to cover the spread. For all of your college basketball bets, be sure to find the best lines by using our live NCAAB odds page.
Queens vs Purdue Odds
| Queens Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+25.5 -110 | 162.5 -115o / -105u | +3500 |
| Purdue Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-25.5 -110 | 162.5 -115o / -105u | -20000 |
- Queens vs Purdue spread: Purdue -25.5
- Queens vs Purdue over/under: 162.5 points
- Queens vs Purdue moneyline: Queens +3500, Purdue -20000
Queens vs Purdue College Basketball Betting Preview
Purdue was the No. 1 team in the land when the season began thanks to the return of its backcourt Braden Smith and Fletcher Loyer, alongside big man Trey Kaufman-Renn.
But ultimately, the Boilers didn't live up to expectations, finishing in a tie for sixth place in the Big Ten regular-season standings.
At least, that was until they ripped through the Big Ten Tournament, winning the title behind four wins against Northwestern, Nebraska, UCLA and, of course, Michigan.
Now the Boilers enter the NCAA Tournament with massive momentum and a much better seed (No. 2) than expected before March began.
This all leads to Purdue covering the spread, right? No, that's wrong, as one of our Bet Labs Sports Insights & Action Network systems is on Queens +25.5.
This system is strong, with an A- grade and a 4% return on investment since its inception.
This criteria is simple: If you're a team between a seven and 16-seed in the NCAA Tournament and you play at a pace lower than 72.2 possessions on average, then you qualify.
With a 307-264-11 total record, I'm trusting this over Purdue's momentum pushing it to cover this large spread.
My Pick: Queens +25.5
