Iowa vs. Iowa State Odds & Betting Predictions - September 6, 2025
Iowa at Iowa State
4:00 pm • FOXIowa at Iowa State Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Iowa 5-1 | +2 | +3.5-118 | o42.5-115 | +140 |
Iowa State 3-3 | u45.5 | -3.5-110 | u42.5-115 | -170 |

Jack Trice StadiumAmes
Iowa vs. Iowa State Expert Picks
Collin Wilson
Last 30d: 84-62-1 (+11.4u)
Over 37.5 (Live)-110
0.55u
New Owner
Last 30d: 0-0-0 (+0.0u)
IOWA +3.5 (Live)+105
0.53u
The Degenerates
Last 30d: 56-48-1 (+5.0u)
Under 41.5-108
1u
Mjaybrod
Last 30d: 56-77-1 (-18.2u)
ISU u23.5 Team Total-110
0.91u
This is how I tail Biev
Action Analytics
Last 30d: 5-12-0 (-9.4u)
R.Becht o226.5 Pass Yds-115
1.15u
IOWA +3.5-115
1u
Sir Lockselot
Last 30d: 10-35-0 (-8.6u)
IOWA +145
3u
📚Player Profit
🔑 Iowa ML +145 (Player Profit) 3u
Getting it going early with a 3u hammer. Iowa’s run-heavy offense plays well against a weak run D in Iowa St. huge rivalry game, spread only 3.5, value in the ML dog. Think Iowa gets it done today on the road
Code: sirlocks for 10% off every purchase at playerprofit.com

Sean Zerillo
Last 30d: 101-106-5 (-3.0u)
IOWA +3.5-110
0.25u
Jeremiah Rose
Last 30d: 50-51-2 (-5.4u)
ISU -2.5-130
0.77u
Big Bets On Campus (CFB)
Last 30d: 51-58-0 (-8.0u)
IOWA +3.5-110
0.91u
@Stuckey2 @_Collin1 https://myaction.app/jBs4sSa5pWb
Brian Bitler
Last 30d: 65-78-4 (-33.2u)
IOWA +3.5-110
2.73u
Doug Ziefel
Last 30d: 342-396-9 (+4.4u)
M.Gronowski u145.5 Pass Yds-115
0.5u
Collin Wilson
Last 30d: 84-62-1 (+11.4u)
IOWA +3.5-115
1u
As discussed on BBOC Podcast
Allan Lem
Last 30d: 43-33-1 (+0.6u)
B.Eskildsen u37.5 Rec Yds-109
0.55u
Tailing @MrTuttle05
Collin Whitchurch
Last 30d: 83-115-2 (-3.3u)
B.Eskildsen u37.5 Rec Yds-109
0.55u
Dan Gaspar
Last 30d: 40-24-0 (+13.1u)
B.Eskildsen u37.5 Rec Yds-109
1.09u
Mike Calabrese
Last 30d: 45-56-0 (+9.6u)
IOWA +130
1u
They didn’t put much on film through the air against Albany and that was on purpose. Iowa State is going to be surprised by Iowa’s passing sophistication. #CyHawk ⚫️🟡🦅
Sandy Plashkes
Last 30d: 103-81-3 (+45.0u)
IOWA +3-110
1.1u
New Owner
Last 30d: 0-0-0 (+0.0u)
IOWA +3.5-118
0.85u
@braydenhenry
Tyler Shoemaker
Last 30d: 81-105-1 (-17.8u)
IOWA +124
4.03u
Doug Ziefel
Last 30d: 342-396-9 (+4.4u)
Under 43.5-110
0.5u
Road to CFB
Last 30d: 30-19-0 (+8.2u)
ISU -2.5-105
1u
Iowa vs. Iowa State Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Iowa vs. Iowa State Public Betting Percentages
Betting Trends
- Iowa State are 3-2 in their last 5 games.
- Iowa State are 2-2 in their last 5 games against the spread
- Iowa State are 1-1 in their road games against the spread
- The totals have gone OVER in 3 of Iowa State' last 5 games
- The totals have gone OVER in 3 of Iowa State' 4 last games at home
Matchup History
Against the Spread (ATS) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 2-3-1 | 1-2-1 | 1-1 | 1-1-1 | 1-2 | |
| 4-2 | 2-2 | 2-0 | 1-1 | 2-1 |
Over/Under History
| overall | home o/u | away o/u | favorite o/u | underdog o/u | |
|---|---|---|---|---|---|
| 3-3 | 3-1 | 0-2 | 2-1 | 1-2 | |
| 2-4 | 1-3 | 1-1 | 0-2 | 1-2 |
Straight-Up (ML) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 3-3 | N/A | N/A | 3-0 | 0-3 | |
| 5-1 | N/A | N/A | 2-0 | 2-1 |
Last 5 Matchups
Team Stats
214
Total Yards
238
63
Total Plays
57
3.3968253968253967
Yards Per Play
4.175438596491228
83
YDS
134
13/24
Comps/Atts
18/27
3.4583333333333335
YPA
4.962962962962963
0/1
TDs/INTs
1/0
3/17
Sacks/Yards
0/0
4/38
Penalties/Yards
5/42
Iowa vs. Iowa State Odds Comparison
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Iowa at Iowa State Team Totals
MatchupOverUnder | ||
|---|---|---|
Iowa 5-1 | N/A | N/A |
Iowa State 3-3 | N/A | N/A |






