Iowa vs. Iowa State Odds & Betting Predictions - September 6, 2025
Iowa at Iowa State
4:00 pm • FOXIowa at Iowa State Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
---|---|---|---|---|
![]() Iowa 5-2 | +2 | +3.5-118 | o42.5-115 | +140 |
![]() Iowa State 5-2 | u45.5 | -3.5-110 | u42.5-115 | -170 |

Jack Trice StadiumAmes
Iowa vs. Iowa State Expert Picks

Collin Wilson
Last 30d: 81-65-1 (+8.3u)
Over 37.5 (Live)-110
0.55u

Boomer Betz
Last 30d: 165-153-2 (+12.1u)
IOWA +3.5 (Live)+105
0.53u

The Degenerates
Last 30d: 60-53-0 (+2.8u)
Under 41.5-108
1u

Mjaybrod
Last 30d: 74-99-1 (-18.2u)
ISU u23.5 Team Total-110
0.91u
This is how I tail Biev

Capper Central
Last 30d: 81-65-0 (+3.0u)
IOWA +3.5-110
1u

Sir Lockselot
Last 30d: 32-61-0 (-15.6u)
IOWA +145
3u
📚Player Profit
🔑 Iowa ML +145 (Player Profit) 3u
Getting it going early with a 3u hammer. Iowa’s run-heavy offense plays well against a weak run D in Iowa St. huge rivalry game, spread only 3.5, value in the ML dog. Think Iowa gets it done today on the road
Code: sirlocks for 10% off every purchase at playerprofit.com

Sean Zerillo
Last 30d: 113-126-5 (+2.9u)
IOWA +3.5-110
0.25u

Jeremiah Rose
Last 30d: 33-23-0 (+1.6u)
ISU -2.5-130
0.77u

Big Bets On Campus (CFB)
Last 30d: 41-47-3 (-8.5u)
IOWA +3.5-110
0.91u
@Stuckey2 @_Collin1 https://myaction.app/jBs4sSa5pWb

Brian Bitler
Last 30d: 64-57-2 (+9.8u)
IOWA +3.5-110
2.73u

Collin Wilson
Last 30d: 81-65-1 (+8.3u)
IOWA +3.5-115
1u
As discussed on BBOC Podcast

Allan Lem
Last 30d: 126-99-5 (+7.5u)
B.Eskildsen u37.5 Rec Yds-109
0.55u
Tailing @MrTuttle05

Dan Gaspar
Last 30d: 36-36-4 (-4.2u)
B.Eskildsen u37.5 Rec Yds-109
1.09u

Mike Calabrese
Last 30d: 29-40-0 (-7.7u)
IOWA +130
1u
They didn’t put much on film through the air against Albany and that was on purpose. Iowa State is going to be surprised by Iowa’s passing sophistication. #CyHawk ⚫️🟡🦅

Sandy Plashkes
Last 30d: 94-98-2 (-0.2u)
IOWA +3-110
1.1u

Boomer Betz
Last 30d: 165-153-2 (+12.1u)
IOWA +3.5-118
0.85u
@braydenhenry

Ryan Sura
Last 30d: 93-101-1 (-8.5u)
IOWA +3-110
1.1u
Iowa vs. Iowa State Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Iowa vs. Iowa State Public Betting Percentages
Betting Trends
- Iowa State are 4-1 in their last 5 games.
- Iowa State are 3-2 in their last 5 games against the spread
- Iowa State are 0-3 in their road games against the spread
- The totals have gone OVER in 3 of Iowa State' last 5 games
- The totals have gone OVER in 2 of Iowa State' 3 last games at home
Matchup History
Against the Spread (ATS) History
overall | home | away | favorite | underdog | |
---|---|---|---|---|---|
![]() | 3-4 | 2-1 | 0-3 | 2-3 | 1-1 |
![]() | 5-2 | 2-2 | 3-0 | 2-2 | 2-0 |
Over/Under History
overall | home o/u | away o/u | favorite o/u | underdog o/u | |
---|---|---|---|---|---|
![]() | 3-4 | 2-1 | 1-2 | 2-3 | 1-1 |
![]() | 3-4 | 2-2 | 1-2 | 2-2 | 0-2 |
Straight-Up (ML) History
overall | home | away | favorite | underdog | |
---|---|---|---|---|---|
![]() | 5-2 | N/A | N/A | 4-1 | 1-1 |
![]() | 5-2 | N/A | N/A | 4-0 | 0-2 |
Last 5 Matchups
Team Stats
214
Total Yards
238
63
Total Plays
57
3.3968253968253967
Yards Per Play
4.175438596491228
83
YDS
134
13/24
Comps/Atts
18/27
3.4583333333333335
YPA
4.962962962962963
0/1
TDs/INTs
1/0
3/17
Sacks/Yards
0/0
4/38
Penalties/Yards
5/42
Iowa vs. Iowa State Odds Comparison
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Iowa at Iowa State Team Totals
MatchupOverUnder | ||
---|---|---|
![]() Iowa 5-2 | o19.5-126 | u19.5-105 |
![]() Iowa State 5-2 | o23.5-109 | u23.5-121 |