Michigan St vs. Notre Dame Odds & Betting Predictions - September 19, 2026
Michigan St at Notre Dame
11:30 pm • NBC/PeacockMichigan St at Notre Dame Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Michigan St 2-6 | +29.5 | +28.5-110 | o51.5-108 | +2000 |
Notre Dame 6-1 | u52.5 | -28.5-108 | u51.5-110 | -5000 |

Notre Dame StadiumSouth Bend
Michigan St vs. Notre Dame Expert Picks
Doug Ziefel
Last 30d: 414-387-9 (+40.1u)
C.Edwards Anytime TD Scorer Yes+210
0.24u
A.Williams Anytime TD Scorer Yes-220
0.5u
Ryan Minion
Last 30d: 231-233-2 (+7.7u)
ND o40.5-122
$1.22
OldSchool0909
Last 30d: 49-48-1 (+1.7u)
MSU +18.5 (Live)-112
2.23u
MSU +29.5-114
0.88u
Michigan St vs. Notre Dame Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Michigan St vs. Notre Dame Public Betting Percentages
Betting Trends
- Notre Dame are 4-1 in their last 5 games.
- Notre Dame are 3-2 in their last 5 games against the spread
- Notre Dame are 1-2 in their road games against the spread
- The totals have gone OVER in 5 of Notre Dame' last 5 games
- The totals have gone OVER in 1 of Notre Dame' 3 last games at home
Matchup History
Against the Spread (ATS) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 4-3 | 2-1 | 1-2 | 2-3 | N/A | |
| 4-4 | 3-2 | 1-2 | 1-1 | 3-3 |
Over/Under History
| overall | home o/u | away o/u | favorite o/u | underdog o/u | |
|---|---|---|---|---|---|
| 5-2 | 1-2 | 3-0 | 4-1 | N/A | |
| 2-6 | 2-3 | 0-3 | 1-1 | 1-5 |
Straight-Up (ML) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 6-1 | N/A | N/A | 4-1 | N/A | |
| 2-6 | N/A | N/A | 2-0 | 0-6 |
Last 5 Matchups
Team Stats
167
Total Yards
395
45
Total Plays
67
3.7111111111111112
Yards Per Play
5.895522388059701
123
YDS
234
9/18
Comps/Atts
18/24
6.833333333333333
YPA
9.75
0/2
TDs/INTs
0/0
4/35
Sacks/Yards
1/1
2/30
Penalties/Yards
3/30
Michigan St vs. Notre Dame Odds Comparison
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Michigan St at Notre Dame Team Totals
MatchupOverUnder | ||
|---|---|---|
Michigan St 2-6 | N/A | N/A |
Notre Dame 6-1 | N/A | N/A |




