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Eastern Michigan vs Central Michigan Prediction, Pick, College Football Odds for Saturday, September 27

Eastern Michigan vs Central Michigan Prediction, Pick, College Football Odds for Saturday, September 27 article feature image
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Rick Osentoski-Imagn Images. Pictured: Joe Labas (Central Michigan)

The Eastern Michigan Eagles take on the Central Michigan Chippewas in Mount Pleasant, Michigan. Kickoff is set for 1 p.m. ET on ESPN+.

Central Michigan is favored by -5.5 points on the spread with a moneyline of -225. The total is set at 53.5 points.

Here’s my Eastern Michigan vs. Central Michigan prediction and college football picks for Saturday, September 27, 2025.

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Eastern Michigan vs Central Michigan Prediction

  • Eastern Michigan vs. Central Michigan Pick: Under 53.5

My Central Michigan vs. Eastern Michigan best bet is on the under. Find the best line available on our live NCAAF odds page.


Eastern Michigan vs Central Michigan Odds

Eastern Michigan Logo
Saturday, September 27
1 p.m. ET
ESPN+
Central Michigan Logo
Eastern Michigan Odds
SpreadTotalMoneyline
+5.5
-110
53.5
-110o / -110u
+185
Central Michigan Odds
SpreadTotalMoneyline
-5.5
-110
53.5
-110o / -110u
-225
Odds via bet365. Get up-to-the-minute NCAAF odds here.
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  • Eastern Michigan vs Central Michigan point spread: Central Michigan -5.5
  • Eastern Michigan vs Central Michigan over/under: 53.5 points
  • Eastern Michigan vs Central Michigan moneyline: Eastern Michigan +185, Central Michigan -225
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Eastern Michigan vs Central Michigan Pick, Betting Analysis

MAC opponents and rivals Eastern Michigan and Central Michigan go toe-to-toe this week at Kelly/Shorts Stadium. The Eagles haven't won in Mount Pleasant (at Central Michigan) since 2011 (!) and are looking to avoid a 1-4 start to the season.

While the spread (rightfully) favors the home Chippewas, the total is where our expert Evan Abrams has a system lighting up.

"Windy 1H Unders" says to target under 53.5, and with a 4% return on investment (ROI) since inception and a 44% ROI this season to date, this system has reliable numbers to back its theory.

In college football, windy conditions have long been an equalizer, especially in the first half when teams are still settling into rhythm. As of writing, Mount Pleasant, Michigan, could have gusts up to 28 mph for this rivalry affair on Saturday.

The "Windy 1H Unders" system takes advantage of how strong winds disrupt passing accuracy, limit explosive plays and force offenses to lean more heavily on the run.

With average wind speeds climbing above 11 miles per hour, deep throws become risky and special teams often struggle to flip field position.

As the market reacts and totals drop from open to close, value emerges on the under before halftime when adjustments have yet to be made.

This angle captures how nature itself can suppress scoring, particularly early, before fatigue or desperation shifts play calling.

Pick: Under 53.5



Eastern Michigan vs Central Michigan Betting Trends



Eastern Michigan vs Central Michigan Weather


Get the latest coverage on NCAAF Weather.

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