The Marshall Thundering Herd take on the Appalachian State Mountaineers in Boone, North Carolina. Kickoff is set for 2:30 p.m. EST on ESPN+.
Marshall is favored by 4.5 points on the spread with a moneyline of -200. The total is set at 55 points.
Here’s my Marshall vs. App State prediction and college football picks for Saturday, November 22, 2025.
Marshall vs App State Prediction
- Marshall vs. App State Pick: App State +4.5 (-110, bet365)
My App State vs. Marshall best bet is on the Mountaineers to cover. Find the best line available on our live NCAAF odds page.
Marshall vs App State Odds
| Marshall Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-4.5 -110 | 55 -110o / -110u | -200 |
| App State Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+4.5 -110 | 55 -110o / -110u | +165 |
- Marshall vs App State point spread: Marshall -4.5 (-110), App State +4.5 (-110)
- Marshall vs App State over/under: 55 (-110o / -110u)
- Marshall vs App State moneyline: Marshall -200, App State +165
Marshall vs App State Game Preview
This game triggered one of our Action PRO betting systems, powered by Evan Abrams.
Mature Market Moves is a college football system that capitalizes on the influence of sharp money when it differs meaningfully from public betting patterns.
In the regular season, when the spread falls between 1 and 6 points, these games are often competitive and decided by narrow margins, making line efficiency critical.
By isolating matchups where the percentage of money wagered is significantly higher than the percentage of tickets, the system highlights situations where larger, more informed bets are backing one side while casual bettors are spread differently.
Limiting the sample to Weeks 5 and later ensures teams have established trends and reliable data to target sharper action.
This combination of tight spreads, mature markets, and a clear split between sharp money and public opinion creates an edge in which following the money side outperforms expectations.
Pick: App State +4.5 (-110, bet365)
