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How to Bet Monday Night Football’s 49ers vs. Cardinals: How Large Underdogs Have Fared This Season

How to Bet Monday Night Football’s 49ers vs. Cardinals: How Large Underdogs Have Fared This Season article feature image

Nick Cammett/Diamond Images via Getty Images. Pictured: Cardinals’ J.J. Watt and Deandre Hopkins

Underdogs of a touchdown or more against the spread have covered 66% of the time (23-12-1) this season.

That's after a Sunday that saw the Panthers cover as +12.5 underdogs to the Ravens and the Browns push as +8 dogs to the Bills.

$500 per game bettors would be up $4,510 by simply betting ATS every time a team was +7 on the spread or more–that's a 25% ROI.

(Hat tip to the Action Network's director of research Evan Abrams for this tidbit.)

For Monday Night Football's 49ers vs. Cardinals, the best price on the market for the underdog is with BetRivers at +10.5 (-125).

This betting system applies its principles indiscriminately. Meaning, even with backup QBs, mass injuries or blustery weather conditions, teams that are +7 or more on the spread have covered at a 66% rate since the beginning of September.

So, even without Kyler Murray at the helm for the Cardinals, fret not if you're bullish on this trend.

There's another simple data point to glean: Underdogs that have a spread of +3 or more have been doing fantastic this season, too.

Teams with a spread between +3 and +11 have covered 61% of the time (64-41-4) over more of a sample size.

A $500 per game bettor would be up $8,635 by betting all 99 games that have fit those parameters this season. That's a 16% ROI.

Both those betting systems fit the Cardinals' spread at +10.5 (-125).

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But while Monday might be the day to cash in, do keep in mind that this is a betting trend that applies to several games per week.

The 25% and 16% ROIs were accrued over a two-and-a-half month long sample size.

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