The Week 12 slate concludes with Monday Night Football featuring the Carolina Panthers and San Francisco 49ers on November 24. Kickoff from Levi's Stadium is set for 8:15 p.m. ET. The game will be broadcast live on ESPN.
Our player props for this Monday Night Football game target Christian McCaffrey, George Kittle, Tetairoa McMillan and Xavier Legette.
Let's dive into my Panthers vs 49ers player props for Monday Night Football.
Panthers vs 49ers Player Props
- Christian McCaffrey Over 5.5 Receptions (+106; FanDuel)
- George Kittle Over 56.5 Receiving Yards (-112; DraftKings)
- Tetairoa McMillan Over 5.5 Receptions (+122; DraftKings)
- Xavier Legette Longest Reception Over 13.5 Yards (-108; FanDuel)
Panthers vs 49ers Prop Picks, Preview
Christian McCaffrey Over 5.5 Receptions (+106)
You didn’t think we’d have a 49ers props piece and not mention Christian McCaffrey, did you? There aren’t many playmakers like McCaffrey in the NFL, let alone on the Niners roster, so we have to back him, especially since he’s having a season like this.
He’s so much more than a running back and his importance in the passing game is huge, with five of his 11 touchdowns this season coming from the air.
McCaffrey's reception line for this game stands at 5.5, which seems low. He’s exceeded that in eight of his 11 games this season and has had six or more targets in every single game.
Only four teams have given up more receptions to running backs than the Panthers, who are allowing 4.9 per game.
Given how much the 49ers look to get McCaffrey the ball in the open field, it stands to reason that he should see a lot of targets here and could convert that into six or more receptions.
Pick: Christian McCaffrey Over 5.5 Receptions (+106; DraftKings)
George Kittle Over 56.5 Receiving Yards (-112)
Only three teams in the NFL have given up more receiving yards to tight ends than the Panthers. It’s interesting because this isn’t a defense that’s been a pass funnel, but a staggering 65.2% of the 212.8 receiving yards they allow per game come from TEs.
Now it’s their turn to face the 49ers and George Kittle, with the former Iowa man being one of the very best in the business. He missed five games earlier in the season with an injury, but besides that has had a big year, with five touchdowns in six games and an average of 41.8 yards per game.
Given the weakness that Monday’s opposition has to tight ends, it’s worth backing him to go over here. It’s also worth flagging that upon Brock Purdy’s return to action last week, we saw Kittle catch all six of his targets for 67 yards.
Pick: George Kittle Over 56.5 Receiving Yards (-112; DraftKings)
Tetairoa McMillan Over 5.5 Receptions (+122)
We’ve seen Tetairoa McMillan show his class for the Panthers since Week 1, but last week saw his true breakout, with 130 yards and two touchdowns. He’s really showing why he was picked eighth overall in April and looks like he could be a potential volume monster in the future.
Last week saw a season high in both receptions (eight) and targets (12), and the good news is that only one team has given up more receptions to wide receivers than the 49ers this year.
McMillan has only had over 5.5 receptions in two of his four games over the past month, but he’s had a lot of targets in that time, with six, eight, 10 and 12 in that span.
Pick: Tetairoa McMillan Over 5.5 Receptions (+122; DraftKings)
Xavier Legette Longest Reception Over 13.5 Yards (-108)
With McMillan showing why he was so highly drafted and Jalen Coker looking good, it feels like Xavier Legette is the forgotten man on the Panthers' roster.
However, he had eight targets last week and is still very much part of their game plan.
The 24-year-old’s longest reception line for the game is set at 13.5 and we have to auto-smash the Over on that. He’s fresh from having a 36-yard reception against the Falcons and has had a reception of 14 or more yards in five of his past seven games.
Pick: Xavier Legette Longest Reception Over 13.5 Yards (-108; FanDuel)
Editor's Note: A parlay isn't the author's formal recommendation. These prop picks have value on their own.
Panthers vs 49ers Prop Bets
- Christian McCaffrey Over 5.5 Receptions (+106; FanDuel)
- George Kittle Over 56.5 Receiving Yards (-112; DraftKings)
- Tetairoa McMillan Over 5.5 Receptions (+122; DraftKings)
- Xavier Legette Longest Reception Over 13.5 Yards (-108; FanDuel)
