Vincent Carchietta, USA Today Sports. Pictured: Jameis Winston
Betting odds: San Francisco 49ers at Tampa Bay Buccaneers
- Spread: Buccaneers -2.5
- Over/Under: 54
- Time: 1 p.m. ET
- TV channel: FOX
>> All odds as of Saturday morning. Download The Action Network App to get real-time NFL odds and track your bets
Betting market: As was the case in Nick Mullens’ second start, the 49ers are getting fewer than 50% of spread bets at the time of writing, but the line is moving in their favor.
They’ve moved from +4 at some books all the way down to +2.5 (see live betting data here). —Mark Gallant
Trends to know: The Niners had their bye week in Week 11. According to our Bet Labs data, bad teams that have won 25% or less of their games, like San Francisco, playing on the road with 13 or more days to prepare for an opponent have gone 30-18 ATS since 2003. — John Ewing
Jameis Winston is scheduled to start for Tampa Bay. In his career, Winston is 4-10 as a favorite (-6.3 units). He is the second-least profitable quarterback as a favorite since he was drafted in 2015, ahead of only Matt Ryan. — Evan Abrams