The best Patriots vs. Seahawks bets for tonight's NFL opener center on New England +3.5 and Under 44.5 in a Super Bowl LX rematch that should be closer than February's 29-13 Seattle win. Patriots vs. Seahawks kicks off at 8:20 p.m. ET on NBC and Peacock from Lumen Field, with the Seahawks favored by 3.5 points and the total set at 44.5.
New England getting more than a field goal and a relatively modest game total create two of the best Patriots vs. Seahawks bets on the board before kickoff. Eligible new users can also claim the bet365 bonus code offer, which awards $365 in bonus bets after a qualifying $10 wager, win or lose.

Best Patriots vs. Seahawks Bets Today
Check out the latest NFL odds for the Patriots vs. Seahawks game. Once you see a market you like, bet on it with your offer from the bet365 bonus code.
| Bet | Current Odds |
|---|---|
| Patriots +3.5 | -115 |
| Under 44.5 | -110 |
Option 1: Patriots +3.5 (-115)
New England has had seven months to adjust after Seattle's defense controlled the Super Bowl matchup, and Drake Maye enters the rematch with A.J. Brown added to his receiving corps.
Seattle still deserves to be favored at Lumen Field, but the Seahawks have undergone more offensive turnover since February. Getting more than a field goal gives New England enough protection to make the Patriots +3.5 my preferred side.
Option 2: Under 44.5 (-110)
The under provides another way to approach a matchup built around two defenses capable of controlling stretches of the game. Seattle held New England to 13 points in Super Bowl LX, while the Patriots should enter the rematch with a more conservative approach designed to keep Maye out of the long-yardage situations that caused problems in February.
Seattle's offensive changes also create some early-season uncertainty. With a new offensive coordinator and changes in the backfield, I prefer the under rather than relying on either offense to push this game into the upper 40s.
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Patriots vs. Seahawks Odds
| Team | Spread | Moneyline | Total |
|---|---|---|---|
| New England Patriots | +3.5 (-115) | +155 | Over 44.5 (-110) |
| Seattle Seahawks | -3.5 (-105) | -185 | Under 44.5 (-110) |
Seattle remains favored after beating New England 29-13 in Super Bowl LX, but the spread is much closer than the margin from February's championship game.
The Seahawks only need to win outright to justify the -185 moneyline, while Patriots +3.5 gives New England room to lose by a field goal and still cover.
Patriots vs. Seahawks Prediction
New England should be better equipped for the rematch after adding Brown to Maye's offense, and getting more than a field goal creates a better entry point than taking the Patriots outright at +155.
- Patriots vs. Seahawks prediction: Patriots +3.5.
Seattle's defense and home-field advantage make the Seahawks difficult to fade completely, but the current spread gives New England enough cushion for me to take the points.
For additional Week 1 analysis, the NFL picks page covers the rest of the opening slate.
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Bottom Line
The best Patriots vs. Seahawks bets for Wednesday's opener are Patriots +3.5 and Under 44.5 at the current numbers. New England has improved since the Super Bowl loss, while Seattle enters Week 1 with enough offensive turnover to make laying more than a field goal less appealing.
The bet365 bonus code offer provides a secondary way for eligible new users to approach the game. Place a qualifying $10 wager and receive $365 in bonus bets after it settles, win or lose.
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