Astros vs. Cubs Odds & Betting Predictions - May 23, 2026
Astros at Cubs
6:20 pm • MARQStarting Pitchers
| pitcher | team | era | w-l | |
|---|---|---|---|---|
 |  | 4.34 | 8-8 | |
 |  | 4.76 | 5-7 |
Astros at Cubs Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Astros 0-2 | +1.5 | +1.5-179 | o7-113 | +125 |
Cubs 0-2 | u7.5 | -1.5+151 | u7-105 | -149 |
Wrigley FieldChicago
Astros vs. Cubs Expert Picks
Sean Zerillo
Last 30d: 152-142-7 (+2.9u)
Under 7.5-115
0.5u
Bet to 7 (-110)
Doug Ziefel
Last 30d: 460-440-10 (+41.5u)
Under 7.5-115
0.5u
C.Rea u17.5 Outs-105
0.53u
Brian Bitler
Last 30d: 71-87-4 (-44.1u)
HOU +138
4.14u
Nick Martin
Last 30d: 34-28-0 (+12.5u)
CHC -140
1u
Frank Ammirante
Last 30d: 108-102-0 (-9.2u)
Under 3.5 (F5)+110
1u
K.Teng u3.5 Hits Allowed+120
1u
C.Rea o4.5 Ks+103
0.97u
Adam Kaufman
Last 30d: 372-345-17 (-10.9u)
HOU +130
1.3u
Wags Wins
Last 30d: 273-252-4 (+15.0u)
HOU +135
1.35u
Astros vs. Cubs Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Astros vs. Cubs Public Betting Percentages
Betting Trends
- Cubs are 1-4 in their last 5 games.
- Cubs are 0-5 in their last 5 games against the spread
- Cubs are 42-38 in their road games against the spread
- The totals have gone OVER in 2 of Cubs' last 5 games
- The totals have gone OVER in 45 of Cubs' 81 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Astros vs. Cubs Injury Updates
Astros Injuries
Cubs Injuries
- Tyler Austin1B
Austin is out with knee
Out
- Justin SteeleSP
Steele is out with elbow
Out
Astros vs. Cubs Box Score
Astros Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
 | 89 | 6 | 6 | 0 | |
 | 11 | 1 | 1 | 0 | |
 | 8 | 1 | 1 | 0 | |
 | 21 | 1 | 1 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
 | 0-4 | 0 | 0 | 0 |
 | 1-3 | 0 | 0 | 0 |
 | 0-2 | 1 | 0 | 0 |
 | 0-1 | 0 | 0 | 0 |
| 0-1 | 0 | 0 | 0 |
 | 3-3 | 2 | 2 | 3 |
 | 0-4 | 0 | 0 | 0 |
 | 0-0 | 0 | 0 | 0 |
 | 1-4 | 0 | 0 | 0 |
 | 0-3 | 0 | 0 | 0 |
 | 0-0 | 0 | 0 | 0 |
 | 1-4 | 0 | 0 | 0 |
| 1-4 | 0 | 0 | 0 |
| 1-4 | 0 | 0 | 0 |
 | 0-3 | 0 | 0 | 0 |
Cubs Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
 | 98 | 7 | 4 | 3 | |
 | 14 | 1 | 0 | 0 | |
 | 16 | 1 | 1 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
 | 1-4 | 0 | 0 | 0 |
 | 1-4 | 0 | 0 | 0 |
 | 0-4 | 0 | 0 | 0 |
 | 0-2 | 0 | 0 | 0 |
 | 0-2 | 0 | 0 | 0 |
 | 0-1 | 0 | 0 | 0 |
| 0-1 | 0 | 0 | 0 |
 | 0-3 | 0 | 0 | 0 |
 | 0-1 | 0 | 0 | 0 |
 | 0-2 | 0 | 0 | 0 |
 | 0-1 | 0 | 0 | 0 |
 | 0-0 | 0 | 0 | 0 |
 | 1-3 | 0 | 0 | 0 |
Astros vs. Cubs Odds Comparison
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Astros at Cubs Team Totals
MatchupOverUnder | ||
|---|---|---|
Astros 0-2 | N/A | N/A |
Cubs 0-2 | N/A | N/A |