Astros vs. Guardians Odds & Betting Predictions - June 7, 2025

Astros at Guardians

8:10 pm • SCHN
5 - 3
Starting Pitchers
pitcherteameraw-l
Gavin Williams logoG.WilliamsCleveland Guardians logo3.546-4
Hunter Brown logoH.BrownHouston Astros logo2.579-4

Astros at Guardians Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Astros
60-43
-1.5
-1.5+152
o6.5-124
-116
Guardians
51-51
u7
+1.5-185
u6.5+102
-105
location pinSaturday 8:10 p.m.
June 07, 2025
Progressive FieldCleveland
Astros vs. Guardians Expert Picks
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 167-176-3 (-36.0u)
Under 6.5+105
1u
Capper Central
Capper Central
Last 30d: 111-81-0 (+15.9u)
CLE +100
1u
Allan Lem
Allan Lem
Last 30d: 52-42-2 (+0.3u)
G.Williams u5.5 Ks-104
0.48u
Tailing @The_Oddsmaker
Sean Koerner
Sean Koerner
Last 30d: 10-19-0 (-6.5u)
G.Williams u5.5 Ks-104
1u
Williams has been dealing lately, clearing this number in 5 of his last 6 starts. But this is a tougher spot to rack up strikeouts. The Astros are a challenging matchup — they have the 8th-lowest whiff rate in the league, swing at the first pitch more than any team, and make contact on pitches in the zone at the 2nd-highest rate. That combo makes it harder for pitchers to get into two-strike counts and harder to finish them off when they do. Williams leans on his sweeper as his top put-away pitch, but Houston is also 8th in whiff rate against sweepers — so they match up well with what he does best. His best K chances are the 4, 7, and 9 hitters, but I’m projecting he gets pulled before facing the 7 and 9 hitters a third time, which caps some of his upside. I have his most likely outcome at 5 Ks and project this closer to -150 to stay under.
Steak Friend
Steak Friend
Last 30d: 0-0-0 (+0.0u)
CLE -103
1.03u
YBK Picks.com
Last 30d: 12-19-2 (-17.3u)
CLE -105
2u
Ray  Monohan
Ray Monohan
Last 30d: 0-0-0 (+0.0u)
CLE -102
0.75u
Picks Office
Picks Office
Last 30d: 80-71-0 (+11.6u)
CLE +105
1u
Wind blowing in 9.2 MPH at Progressive favors the arms – helps suppress Houston’s bats. Astros cooling off: .270 wOBA & 68 wRC+ over last 7 days, both bottom 6 in MLB. Hunter Brown’s still elite but 2.51 road ERA is nearly a full run higher than at home – regression looming. Gavin Williams locked in – 2.30 ERA over last 5 starts. Guardians 4-2 in his home starts. Last outing: 6.2 scoreless, 1 hit vs Angels. Houston’s .253 AVG hiding inefficiency – just 4.03 runs/game (22nd MLB). Cleveland thrives in small-ball spots: bunts, sac flies, situational ABs. Ramírez is the X-factor – .330 AVG, 11 HRs, elite RISP bat. Guardians’ pen underrated, 3.82 ERA (15th) but clutch in close games. Day game + home underdog vibes = edge in motivation. Cleveland’s urgency > Houston’s pressure. Astros won 7 of 8 vs CLE? Payback time.
💰🦡 Jake
💰🦡 Jake
Last 30d: 51-50-1 (+11.7u)
HOU -1.5+150
1.5u
Sandy Plashkes
Sandy Plashkes
Last 30d: 83-77-2 (+10.6u)
CLE +104
1u

Astros vs. Guardians Previews & Analysis

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Astros vs. Guardians Public Betting Percentages

Away Logo

Astros

Public

66%

Bets%

34%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Guardians
53-4924-2629-2321-2032-28
Astros
54-4926-2728-2230-4124-7

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Guardians
44-54-424-25-120-29-321-2023-33-4
Astros
43-55-522-3121-24-533-37-19-18-4

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Guardians
51-5125-2526-2626-1525-35
Astros
60-4333-2027-2341-3019-12

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Jun 6thHOUL 2-4+1.5 LU 8HOU +110
Jun 5th@NYYL 0-4+1.5 LU 8.5NYY +225
Jun 4th@NYYW 4-0+1.5 WU 9CLE +164
Jun 3rd@NYYL 2-3+1.5 WU 8NYY +166
Jun 1stLAAW 4-2-1.5 WU 8CLE -210

Guardians vs. Astros Injury Updates

Guardians Injuries

  • Gabriel Arias
    SS

    Arias is out with leg

    Out

  • Ben Lively
    SP

    Lively is out with elbow

    Out

  • Shane Bieber
    SP

    Bieber is out with elbow

    Out

  • John Means
    SP

    Means is out with elbow

    Out

Astros Injuries

  • Jake Meyers
    CF

    Meyers is out with calf

    Out

  • Cristian Javier
    SP

    Javier is out with elbow

    Out

  • Jeremy Pena
    SS

    Pena is out with ribs

    Out

  • Luis Garcia
    SP

    Garcia is out with elbow

    Out

  • Pedro Leon
    RF

    Leon is out with knee

    Out

  • J.P. France
    SP

    France is out with shoulder

    Out

  • Hayden Wesneski
    RP

    Wesneski is out with elbow

    Out

  • Spencer Arrighetti
    SP

    Arrighetti is out with thumb

    Out

Astros vs. Guardians Box Score
Astros Player Stats
Projected
PITCHERPCIPKER
Hunter Brown logoRH.Brown, P1015.191
Steven Okert logoLS.Okert, P110.221
Shawn Dubin logoRS.Dubin, P24201
Josh Hader logoLJ.Hader, P24120
Bennett Sousa logoLB.Sousa, P18120
HITTERSH-ABRHRRBI
Jeremy Pena logo1J.Pena, SS1-5001
Isaac Paredes logo2I.Paredes, 3B1-5001
Jose Altuve logo3J.Altuve, LF0-5000
Cam Smith logo3C.Smith, RF0-0000
Christian Walker logo4C.Walker, 1B1-4000
Victor Caratini logo5V.Caratini, DH0-3100
Yainer Diaz logo6Y.Diaz, C2-4212
Jake Meyers logo7J.Meyers, CF1-3100
Mauricio Dubon logo8M.Dubon, RF0-4000
Mauricio Dubon logo8M.Dubon, 2B0-4000
Brendan Rodgers logo9B.Rodgers, 2B0-3000
Jacob Melton logo9J.Melton, PH0-0100
Jacob Melton logo9J.Melton, LF0-0100
Guardians Player Stats
Projected
PITCHERPCIPKER
Gavin Williams logoRG.Williams, P92653
Jakob Junis logoRJ.Junis, P12110
Cade Smith logoRC.Smith, P18100
Emmanuel Clase logoRE.Clase, P13110
Hunter Gaddis logoRH.Gaddis, P17101
HITTERSH-ABRHRRBI
Steven Kwan logo1S.Kwan, LF3-4100
Angel Martinez logo2A.Martinez, CF0-4000
Jose Ramirez logo3J.Ramirez, DH2-3212
Kyle Manzardo logo4K.Manzardo, 1B0-4000
Carlos Santana logo4C.Santana, PH0-1000
Carlos Santana logo4C.Santana, 1B0-1000
Daniel Schneemann logo5D.Schneemann, 2B0-4000
Gabriel Arias logo6G.Arias, SS1-4001
Bo Naylor logo7B.Naylor, C0-3000
Nolan Jones logo8N.Jones, RF0-1000
David Fry logo8D.Fry, PH0-1000
Jhonkensy Noel logo8J.Noel, RF0-2000
Will Wilson logo9W.Wilson, 3B0-4000

Astros vs. Guardians Odds Comparison

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Astros at Guardians Team Totals

MatchupOverUnder
Astros
60-43
o3.5+100
u3.5-128
Guardians
51-51
o3.5+118
u3.5-151