Astros vs. Guardians Odds & Betting Predictions - June 6, 2025
Astros at Guardians
11:10 pm • CLEGStarting Pitchers
pitcher | team | era | w-l | |
---|---|---|---|---|
![]() | ![]() | 4.06 | 6-8 | |
![]() | ![]() | 4.53 | 4-2 |
Astros at Guardians Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
---|---|---|---|---|
![]() Astros 60-42 | +1.5 | -1.5+134 | o8-102 | -128 |
![]() Guardians 51-50 | u8.5 | +1.5-163 | u8-118 | +110 |

Progressive FieldCleveland
Astros vs. Guardians Expert Picks

Al’s Analytics
Last 30d: 47-38-0 (+6.2u)
CLE +110
1u

Capper Central
Last 30d: 115-78-0 (+22.7u)
HOU -121
1u

Bet Labs
Last 30d: 22-23-0 (-5.9u)
Under 8.5-115
1u

💰🦡 Jake
Last 30d: 54-48-2 (+17.1u)
Over 8.5+104
1u

Picks Office
Last 30d: 81-71-0 (+12.0u)
HOU -105
0.95u

Derek Carty
Last 30d: 4-12-1 (+0.9u)
Jose Ramirez o0.5 Walks+260
1u
Payoff Pitch: https://myaction.app/X5dMrBQZYTb

Jim Sannes
Last 30d: 19-40-0 (-7.3u)
C.Gordon o4.5 Ks+116
1.16u
Have him projected at 5.12. Won't go deep in games, but he doesn't walk batters, which increases his pitch efficiency, and he gets a boost from a Guardians team that has struggled with strikeouts against lefties this year.

Sean Zerillo
Last 30d: 155-145-11 (+13.4u)
HOU -105 (F5)
0.25u
Small to -120
HOU +105
0.53u
Bet to -104
Astros vs. Guardians Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Astros vs. Guardians Public Betting Percentages
Betting Trends
- Guardians are 4-1 in their last 5 games.
- Guardians are 3-2 in their last 5 games against the spread
- Guardians are 29-23 in their road games against the spread
- The totals have gone OVER in 4 of Guardians' last 5 games
- The totals have gone OVER in 24 of Guardians' 49 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Guardians vs. Astros Injury Updates

Guardians Injuries
- Gabriel AriasSS
Arias is out with leg
Out
- Ben LivelySP
Lively is out with elbow
Out
- Shane BieberSP
Bieber is out with elbow
Out
- John MeansSP
Means is out with elbow
Out

Astros Injuries
- Jake MeyersCF
Meyers is out with calf
Out
- Cristian JavierSP
Javier is out with elbow
Out
- Jeremy PenaSS
Pena is out with ribs
Out
- Luis GarciaSP
Garcia is out with elbow
Out
- Pedro LeonRF
Leon is out with knee
Out
- J.P. FranceSP
France is out with shoulder
Out
- Hayden WesneskiRP
Wesneski is out with elbow
Out
- Spencer ArrighettiSP
Arrighetti is out with thumb
Out
Astros vs. Guardians Box Score

PITCHER | PC | IP | K | ER | |
---|---|---|---|---|---|
![]() | 75 | 5 | 5 | 1 | |
![]() | 14 | 0.2 | 0 | 1 | |
![]() | 19 | 1.1 | 1 | 0 | |
![]() | 14 | 1 | 1 | 0 | |
![]() | 12 | 1 | 2 | 0 |
HITTERS | H-AB | R | HR | RBI |
---|---|---|---|---|
![]() | 3-5 | 1 | 0 | 0 |
![]() | 1-2 | 1 | 0 | 0 |
![]() | 2-5 | 1 | 0 | 1 |
![]() | 1-4 | 0 | 0 | 2 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 1-3 | 1 | 1 | 1 |
![]() | 0-4 | 0 | 0 | 0 |

PITCHER | PC | IP | K | ER | |
---|---|---|---|---|---|
![]() | 88 | 6 | 2 | 4 | |
![]() | 22 | 1 | 0 | 0 | |
![]() | 12 | 1 | 1 | 0 | |
![]() | 21 | 1 | 1 | 0 |
HITTERS | H-AB | R | HR | RBI |
---|---|---|---|---|
![]() | 1-4 | 0 | 0 | 0 |
![]() | 2-3 | 1 | 1 | 1 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 1-4 | 1 | 0 | 0 |
![]() | 2-4 | 0 | 0 | 0 |
![]() | 1-2 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 1-3 | 0 | 0 | 1 |
![]() | 0-3 | 0 | 0 | 0 |
Astros vs. Guardians Odds Comparison
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Astros at Guardians Team Totals
MatchupOverUnder | ||
---|---|---|
![]() Astros 60-42 | o4.5+115 | u4.5-146 |
![]() Guardians 51-50 | o3.5-113 | u3.5-115 |