Astros vs Mariners Odds: Moneyline, Over/Under, Props - September 22, 2026 | The Action Network

Astros at Mariners

1:40 am • SEAM

Houston Astros

7

7 - 0

Seattle Mariners

0

pitcher		team	era	w-l
L.Gilbert			3.73	12-11
C.Javier			5.14	2-6

MatchupOpenSpreadTotalMoneyline
Astros 0-2	+1.5	+1.5-195	o7.5-107	+110
Mariners 0-0	u7.5	-1.5+164	u7.5-115	-133

location pin

Wednesday 1:40 a.m.

September 23, 2026

T-Mobile ParkSeattle

HOU +120

1.2u

Returning Home After Road Trip vs. Division (FADE) Overall: 362-377-1,49% (ROI:14%) Season:11-18-0,38% (ROI:-15%) #TSA

SEA -130

1.3u

Derek Carty's Pick for Astros vs Mariners
Action Network Staff•
Sep 22, 2026 UTC

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MLB Public Betting

Mariners are 3-2 in their last 5 games.
Mariners are 2-3 in their last 5 games against the spread
Mariners are 27-54 in their road games against the spread
The totals have gone OVER in 5 of Mariners' last 5 games
The totals have gone OVER in 41 of Mariners' 81 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Mariners	57-105	30-51	27-54	43-82	12-23
Astros	83-79	39-42	44-37	30-39	51-37

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Mariners	85-70-7	41-36-4	44-34-3	63-56-6	22-12-1
Astros	78-75-9	39-40-2	39-35-7	35-33-1	42-38-8

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Mariners	76-86	43-38	33-48	62-63	12-23
Astros	81-81	39-42	42-39	35-34	44-44

date	opponent	score	spread	over/under	moneyline
Sep 20th	@COL	W 2-1	-1.5 L	U 11	SEA -164
Sep 20th	@COL	L 3-5	-1.5 L	U 10.5	COL -154
Sep 19th	@COL	W 5-4	-1.5 L	U 10.5	SEA -195
Sep 17th	@LAA	W 7-2	-1.5 W	O 8	SEA -135
Sep 16th	@LAA	L 1-2	-1.5 L	U 8	LAA -172

PITCHER		PC	IP	K	ER
RC.Javier, P		45	2	2	0
RM.Ullola, P		33	2	2	0
LB.Sousa, P		40	2	3	0
RA.Blubaugh, P		10	1	0	0
RL. VanWey, P		25	2	2	0

HITTERS	H-AB	R	HR	RBI
1J.Pena, SS	1-4	2	0	0
1N.Allen, SS	0-0	0	0	0
2Y.Alvarez, DH	2-4	1	1	3
3I.Paredes, 3B	2-4	1	1	1
4J.Altuve, 2B	2-5	1	0	0
5Y.Diaz, C	2-5	1	0	0
6C.Walker, 1B	1-5	1	1	3
7T.Trammell, LF	0-3	0	0	0
7T.Trammell, CF	0-3	0	0	0
8C.Smith, RF	1-5	0	0	0
9B.Matthews, CF	1-2	0	0	0
9N.Velazquez, LF	0-1	0	0	0

PITCHER		PC	IP	K	ER
RL.Gilbert, P		81	4	3	4
LJ.Ferrer, P		29	1.2	2	1
RE.Bazardo, P		22	1.1	1	0
RC.Vargas, P		20	1	1	2
RM.Rucker, P		17	1	1	0

HITTERS	H-AB	R	HR	RBI
1J.Crawford, SS	0-3	0	0	0
1J.Crawford, 3B	0-3	0	0	0
2R.Arozarena, LF	0-1	0	0	0
3D.Canzone, DH	1-4	0	0	0
4C.Raleigh, C	0-3	0	0	0
5J.Rodriguez, CF	2-4	0	0	0
6J.Naylor, 1B	0-4	0	0	0
7C.Young, 2B	1-3	0	0	0
7C.Young, SS	1-3	0	0	0
8L.Montes, RF	0-4	0	0	0
9B.Rodden, 3B	0-1	0	0	0
9T.Ward, PH	0-1	0	0	0
9W.Wilson, 3B	0-0	0	0	0
9M.Arroyo, PH	0-2	0	0	0
9M.Arroyo, 2B	0-2	0	0	0

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MatchupOverUnder
Astros 0-2	N/A	N/A
Mariners 0-0	N/A	N/A