Astros vs Mariners Odds: Moneyline, Over/Under, Props - September 22, 2026 | The Action Network

Astros at Mariners

1:40 am • SEAM

Houston Astros

@

Seattle Mariners

pitcher		team	era	w-l
L.Gilbert			0.00	0-0
C.Javier			0.00	0-0

MatchupOpenSpreadTotalMoneyline
Astros 77-78	N/A	N/A	N/A
Mariners 72-83	N/A	N/A	N/A

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Wednesday 1:40 a.m.

September 23, 2026

T-Mobile ParkSeattle

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64°Fahrenheit

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0%Rain

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3Wind

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MLB Public Betting

Mariners are 2-3 in their last 5 games.
Mariners are 1-4 in their last 5 games against the spread
Mariners are 27-53 in their road games against the spread
The totals have gone OVER in 2 of Mariners' last 5 games
The totals have gone OVER in 36 of Mariners' 75 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Mariners	55-100	28-47	27-53	41-77	12-23
Astros	78-77	39-41	39-36	27-37	49-37

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Mariners	80-68-7	36-35-4	44-33-3	58-54-6	22-12-1
Astros	74-72-9	39-39-2	35-33-7	32-31-1	41-37-8

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Mariners	72-83	40-35	32-48	58-60	12-23
Astros	77-78	39-41	38-37	32-32	43-43

date	opponent	score	spread	over/under	moneyline
Sep 20th	@COL	L 3-5	-1.5 L	U 10.5	COL -154
Sep 19th	@COL	W 5-4	-1.5 L	U 10.5	SEA -195
Sep 17th	@LAA	W 7-2	-1.5 W	O 8	SEA -135
Sep 16th	@LAA	L 1-2	-1.5 L	U 8	LAA -172
Sep 15th	@LAA	L 4-6	-1.5 L	O 7.5	LAA -111

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MatchupOverUnder
Astros 77-78	N/A	N/A
Mariners 72-83	N/A	N/A