Astros vs. Orioles Odds & Betting Predictions - August 22, 2025

Astros at Orioles

11:05 pm • MLB Network
7 - 3

Astros at Orioles Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Astros
70-58
-1.5
-1.5+137
o9.5-108
-116
Orioles
59-68
u9
+1.5-164
u9.5-114
-104
location pinFriday 11:05 p.m.
August 22, 2025
Oriole Park at Camden YardsBaltimore
Astros vs. Orioles Expert Picks
VegasIsMyBitch
VegasIsMyBitch
Last 30d: 23-17-1 (+6.1u)
Under 9+101
0.5u
1.5u play overall
Under 9+101
1u
Scott Rickenbach
Scott Rickenbach
Last 30d: 70-74-4 (-14.3u)
Over 9.5-111
1u
Player Prop Savant
Player Prop Savant
Last 30d: 20-35-0 (-16.4u)
HOU o4.5 Team Total-117
1.46u
Derek Carty
Derek Carty
Last 30d: 4-2-4 (+5.0u)
Samuel Basallo o0.5 Hitter BBs+280
1u
Payoff Pitch Podcast
Payoff Pitch Podcast
Last 30d: 5-9-0 (-2.1u)
Samuel Basallo o0.5 Hitter BBs+280
1u

Astros vs. Orioles Previews & Analysis

  • Astros vs Orioles: Bounce Back Spot article feature image

    Astros vs Orioles: Bounce Back Spot

    Sean Paul
    Aug 22, 2025 UTC
  • Friday's MLB Best Bets article feature image

    Friday's MLB Best Bets

    Action Network Staff
    Aug 22, 2025 UTC
See more MLB Coverage Right Arrow

Prop Odds Comparison

Right Arrow
Right Arrow

No props found

Line Movement Tracker

Right Arrow
Right Arrow

Astros vs. Orioles Public Betting Percentages

Away Logo

Astros

Public

60%

Bets%

40%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Orioles
60-6727-3433-3320-3738-30
Astros
64-6430-3534-2934-5130-11

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Orioles
54-69-431-28-223-41-229-26-224-42-2
Astros
59-63-629-35-130-28-540-43-217-20-4

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Orioles
59-6830-3129-3725-3232-36
Astros
70-5838-2732-3146-3924-17

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Aug 21stHOUL 2-7+1.5 LO 8.5HOU -120
Aug 19th@BOSW 4-3+1.5 WU 9.5BAL +125
Aug 18th@BOSW 6-3-1.5 WO 8BAL +105
Aug 17th@HOUW 12-0-1.5 WO 8.5BAL -101
Aug 16th@HOUL 4-5+1.5 WO 8.5HOU +118

Astros vs. Orioles Injury Updates

Astros Injuries

  • Jake Meyers
    CF

    Meyers is out with calf

    Out

  • Luis Garcia
    SP

    Garcia is out with elbow

    Out

  • Pedro Leon
    RF

    Leon is out with knee

    Out

  • J.P. France
    SP

    France is out with shoulder

    Out

  • Hayden Wesneski
    RP

    Wesneski is out with elbow

    Out

Orioles Injuries

  • Albert Suarez
    RP

    Suarez is out with shoulder

    Out

  • Jorge Mateo
    SS

    Mateo is out with hamstring

    Out

  • Kyle Bradish
    SP

    Bradish is out with elbow

    Out

  • Grayson Rodriguez
    SP

    Rodriguez is out with elbow

    Out

  • Tyler Wells
    SP

    Wells is out with elbow

    Out

Astros vs. Orioles Box Score
Astros Player Stats
Projected
PITCHERPCIPKER
Lance McCullers logoRL.McCullers, P87443
Shawn Dubin logoRS.Dubin, P24100
HITTERSH-ABRHRRBI
Jeremy Pena logo1J.Pena, SS1-4113
Carlos Correa logo2C.Correa, 3B1-2100
Jose Altuve logo3J.Altuve, DH1-3100
Christian Walker logo4C.Walker, 1B1-3113
Yainer Diaz logo5Y.Diaz, C0-2000
Ramon Urias logo6R.Urias, 2B1-3000
Mauricio Dubon logo7M.Dubon, LF0-2100
Cam Smith logo8C.Smith, RF0-3100
Chas McCormick logo9C.McCormick, CF0-1100
Orioles Player Stats
Projected
PITCHERPCIPKER
Cade Povich logoLC.Povich, P964.254
Yennier Cano logoRY.Cano, P120.111
Kade Strowd logoRK.Strowd, P12100
HITTERSH-ABRHRRBI
Jackson Holliday logo1J.Holliday, 2B0-1000
Jeremiah Jackson logo2J.Jackson, RF2-3002
Gunnar Henderson logo3G.Henderson, SS1-3000
Ryan Mountcastle logo4R.Mountcastle, DH0-2000
Colton Cowser logo5C.Cowser, CF0-3000
Coby Mayo logo6C.Mayo, 1B0-2100
Dylan Beavers logo7D.Beavers, LF1-2100
Luis Vazquez logo8L.Vazquez, 3B2-3000
Alex Jackson logo9A.Jackson, C2-3101

Astros vs. Orioles Odds Comparison

Right Arrow

Could not load odds

Astros at Orioles Team Totals

MatchupOverUnder
Astros
70-58
N/A
N/A
Orioles
59-68
N/A
N/A