Red Sox vs. Yankees Odds & Betting Predictions - August 21, 2025

Red Sox at Yankees

11:15 pm • FOX
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Starting Pitchers
pitcherteameraw-l
Luis Gil logoL.GilNew York Yankees logo5.141-1
Lucas Giolito logoL.GiolitoBoston Red Sox logo3.638-2

Red Sox at Yankees Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Red Sox
68-59
+1.5
+1.5-175
o8.5-102
+122
Yankees
69-57
u8.5
-1.5+143
u8.5-115
-146
location pinThursday 11:15 p.m.
August 21, 2025
Yankee StadiumBronx
thermometer image71°Fahrenheit
rain image0%Rain
wind image11Wind
Red Sox vs. Yankees Expert Picks
Analytics Trends
Analytics Trends
Last 30d: 44-30-3 (+7.1u)
NYY -145
1u
📊 27-7 W/L (79.41%) ROI ~ 32.87% L10 ~ 7-3 📈 Home Favorite On Win Streak in Series Opener ✅ Team is on 2+ game winning streak ✅ Team is playing against division opponent ✅ Team is favored to win ✅ Team is at home ✅ Game number 1 of series
Markus Markets
Markus Markets
Last 30d: 14-9-1 (+4.2u)
R.Anthony o1.5 Hits + Runs + RBIs-105
1u
Lines at Lunch
Lines at Lunch
Last 30d: 45-50-6 (-8.0u)
J.Chisholm o1.5 Hits + Runs + RBIs+110
0.91u
Ryan Sura
Ryan Sura
Last 30d: 32-37-5 (-4.5u)
J.Chisholm o1.5 Hits + Runs + RBIs+110
1u
Austin Pendergrass
Austin Pendergrass
Last 30d: 62-55-0 (+1.6u)
NYY -140 (F5)
0.5u
Lines at Lunch
Lines at Lunch
Last 30d: 45-50-6 (-8.0u)
BOS +128
0.78u
BOS +0.5 (F5)-120
1.2u
Brian Bitler
Brian Bitler
Last 30d: 80-73-0 (+16.6u)
NYY -148
3u
Sean Zerillo
Sean Zerillo
Last 30d: 152-171-4 (-0.8u)
NYY -135
0.68u
Bet to -143

Red Sox vs. Yankees Previews & Analysis

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Prop Odds Comparison

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Line Movement Tracker

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Red Sox vs. Yankees Public Betting Percentages

Away Logo

Red Sox

Public

45%

Bets%

55%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Yankees
57-6933-2924-4047-599-10
Red Sox
69-5836-3033-2842-3727-19

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Yankees
59-63-426-35-133-28-349-55-29-8-2
Red Sox
62-62-328-36-234-26-140-37-222-23-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Yankees
69-5737-2532-3260-468-11
Red Sox
68-5941-2527-3447-3221-25

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Aug 20th@TBW 6-4-1.5 WO 8.5NYY -106
Aug 19th@TBW 13-3-1.5 WO 8NYY -135
Aug 17th@STLW 8-4-1.5 WO 9NYY -158
Aug 16th@STLW 12-8-1.5 WO 7.5NYY -142
Aug 16th@STLW 4-3-1.5 LU 9NYY -146

Red Sox vs. Yankees Injury Updates

Red Sox Injuries

  • Tanner Houck
    SP

    Houck is out with arm

    Out

  • Patrick Sandoval
    SP

    Sandoval is out with elbow

    Out

  • Kutter Crawford
    SP

    Crawford is out with knee

    Out

  • Jovani Moran
    RP

    Moran is out with arm

    Out

Yankees Injuries

  • Gerrit Cole
    SP

    Cole is out for season with elbow

    Out for Season

  • Austin Slater
    LF

    Slater is out with hamstring

    Out

Red Sox vs. Yankees Starting Lineups
Red Sox Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Lucas Giolito logoRL.Giolito, P8-23.631.2477.34
HITTERSAVGOBPSLGHR
Roman Anthony logo1R.Anthony, LF.283.402.4344
Alex Bregman logo2A.Bregman, 3B.298.384.53316
Jarren Duran logo3J.Duran, CF.261.336.45112
Trevor Story logo4T.Story, SS.259.302.42319
Masataka Yoshida logo5M.Yoshida, DH.235.280.3652
Wilyer Abreu logo6W.Abreu, RF.253.325.48622
Ceddanne Rafaela logo7C.Rafaela, 2B.252.296.42614
Nathaniel Lowe logo8N.Lowe, 1B.250.5001.0001
Carlos Narvaez logo9C.Narvaez, C.245.313.40810
Yankees Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Luis Gil logoRL.Gil, P1-15.141.6439.00
HITTERSAVGOBPSLGHR
Trent Grisham logo1T.Grisham, CF.249.353.46423
Aaron Judge logo2A.Judge, RF.330.445.68440
Cody Bellinger logo3C.Bellinger, LF.272.325.49824
Giancarlo Stanton logo4G.Stanton, DH.311.389.64215
Ben Rice logo5B.Rice, C.239.334.47319
Paul Goldschmidt logo6P.Goldschmidt, 1B.279.332.42510
Jazz Chisholm logo7J.Chisholm, 2B.236.333.47222
Anthony Volpe logo8A.Volpe, SS.213.280.40918
Ryan McMahon logo9R.McMahon, 3B.239.350.3431

Red Sox vs. Yankees Odds Comparison

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Red Sox at Yankees Team Totals

MatchupOverUnder
Red Sox
68-59
N/A
N/A
Yankees
69-57
N/A
N/A