Cubs vs. Cardinals Odds & Betting Predictions - May 31, 2026

Cubs at Cardinals

11:20 pm • NBC/Peacock
1 - 5
Starting Pitchers
pitcherteameraw-l
Matthew Liberatore logoM.LiberatoreSt. Louis Cardinals logo4.363-3
Jordan Wicks logoJ.WicksChicago Cubs logo15.630-2

Cubs at Cardinals Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Cubs
32-28
-1.5
-1.5+156
o8.5-115
+100
Cardinals
31-26
u8.5
-2.5+100
u8.5+100
-120
location pinSunday 11:20 p.m.
May 31, 2026
Busch StadiumSt. Louis
Cubs vs. Cardinals Expert Picks
Matthew Lopes
Matthew Lopes
Last 30d: 1-9-0 (-6.5u)
J.Walker o0.5 HR (Live)+440
1u
YBK Picks.com
Last 30d: 28-21-3 (+12.8u)
Under 8.5-115
1.74u
Scott Rickenbach
Scott Rickenbach
Last 30d: 48-50-2 (-3.6u)
Over 8.5-105
1u
Wags Wins
Wags Wins
Last 30d: 221-278-3 (-80.9u)
Under 8.5-113
1.11u
Sandy Plashkes
Sandy Plashkes
Last 30d: 105-113-3 (-17.2u)
Over 8.5-105
2.1u
Picks Office
Picks Office
Last 30d: 129-135-10 (-14.3u)
STL -110
0.91u
Join Discord for earlier access: https://discord.gg/HjKxYKdSUy Chicago's listed starter has only 4.1 innings this season with a 16.62 ERA and 2.31 WHIP. St. Louis gets the steadier workload profile with Liberatore at 56.2 innings and 11 starts. The Cardinals already lead the season series 2-1, and Chicago is 14-16 away from home.

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Prop Odds Comparison

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Line Movement Tracker

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Cubs vs. Cardinals Public Betting Percentages

Away Logo

Cubs

Public

52%

Bets%

48%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Cardinals
34-2317-1217-114-330-20
Cubs
24-3612-1712-1915-239-13

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Cardinals
24-30-314-14-110-16-22-522-25-3
Cubs
33-2715-1418-1319-1914-8

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Cardinals
31-2615-1416-124-327-23
Cubs
32-2818-1114-1722-1610-12

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 30thCHCL 1-6+1.5 LU 8CHC +111
May 29thCHCW 6-5+1.5 WO 7.5STL +113
May 27th@MILL 1-2+1.5 WU 8MIL +149
May 26th@MILL 0-6+1.5 LU 8MIL +179
May 25th@MILL 1-5+1.5 LU 7.5MIL +193

Cubs vs. Cardinals Injury Updates

Cubs Injuries

  • Tyler Austin
    1B

    Austin is out with knee

    Out

  • Justin Steele
    SP

    Steele is out with elbow

    Out

Cardinals Injuries

  • Lars Nootbaar
    LF

    Nootbaar is out with heel

    Out

Cubs vs. Cardinals Box Score
Cubs Player Stats
Projected
PITCHERPCIPKER
Jordan Wicks logoLJ.Wicks, P49213
Ethan Roberts logoRE.Roberts, P22122
Trent Thornton logoRT.Thornton, P28210
Phil Maton logoRP.Maton, P14110
Ryan Rolison logoLR.Rolison, P34200
HITTERSH-ABRHRRBI
Nico Hoerner logo1N.Hoerner, 2B1-4000
Pete Crow-Armstrong logo2P.Crow-Armstrong, CF1-4000
Alex Bregman logo3A.Bregman, 3B1-4111
Seiya Suzuki logo4S.Suzuki, RF0-4000
Ian Happ logo5I.Happ, LF0-4000
Carson Kelly logo6C.Kelly, C0-4000
Michael Busch logo7M.Busch, 1B2-4000
Kevin Alcantara logo8K.Alcantara, DH1-2000
Michael Conforto logo8M.Conforto, PH1-2000
Michael Conforto logo8M.Conforto, DH1-2000
Dansby Swanson logo9D.Swanson, SS0-2000
Cardinals Player Stats
Projected
PITCHERPCIPKER
Matthew Liberatore logoLM.Liberatore, P855.140
Hunter Dobbins logoRH.Dobbins, P613.241
HITTERSH-ABRHRRBI
JJ Wetherholt logo1J.Wetherholt, 2B2-3200
Ivan Herrera logo2I.Herrera, DH2-3200
Jordan Walker logo3J.Walker, RF1-4001
Nelson Velazquez logo4N.Velazquez, LF1-4000
Alec Burleson logo5A.Burleson, 1B1-3102
Masyn Winn logo6M.Winn, SS1-4002
Jose Fermin logo7J.Fermin, CF0-3000
Victor Scott logo7V.Scott, CF0-1000
Thomas Saggese logo8T.Saggese, 3B0-1000
Nolan Gorman logo8N.Gorman, PH0-1000
Nolan Gorman logo8N.Gorman, 3B0-1000
Pedro Pages logo9P.Pages, C0-2000

Cubs vs. Cardinals Odds Comparison

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Cubs at Cardinals Team Totals

MatchupOverUnder
Cubs
32-28
N/A
N/A
Cardinals
31-26
N/A
N/A