Cubs vs. Padres Odds & Betting Predictions - April 28, 2026

Cubs at Padres

1:40 am • MARQ

Chicago Cubs

37-35

7 - 9

San Diego Padres

37-33

pitcher		team	era	w-l
R.Vasquez			3.63	6-4
M.Boyd			6.00	2-1

MatchupOpenSpreadTotalMoneyline
Cubs 37-35	-1.5	-1.5+160	o7.5-115	+100
Padres 37-33	u8	+1.5-192	u7.5-105	-120

Tuesday 1:40 a.m.

April 28, 2026

Petco ParkSan Diego

Over 13.5 (Live)+190

1.9u

Under 13.5 (Live)-120

1.2u

SD +1.5 (Live)-105

M.Boyd o15.5 Outs (Live)-115

0.85u

CHC -110 (F5)

1.1u

CHC +111

M.Machado o1.5 Total Bases+134

$1.34

Over 7.5-104

I.Happ To Record 2+ Total Bases Yes+175

0.25u

M.Machado To Record 2+ Total Bases Yes+145

0.36u

SD -110

0.91u

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Under 0.5 (1st Inn)-127

1.27u

CHC -105

SD -1.5+180

$1.80

SD +100 (F5)

$1.00

A.Bregman o1.5 Total Bases+165

0.31u

#EV 4.05% Pinny +133 Circa +135 BO +146

P.Crow-Armstrong To Hit 1+ Home Runs Yes+725

0.1u

#EV 5.85% Circa +550

F.Tatis To Hit 1+ Home Runs Yes+600

0.2u

#EV 9.42% Pinny +444 Circa +420

SD -1.5+215

0.62u

#EV 4.95% Pinny +184 Circa +185 FD +182 BO +177

N.Hoerner o1.5 Total Bases+140

0.46u

#EV 5.16% Pinny +109 BO +117

M.Machado o1.5 Total Bases+145

0.73u

@cowhitchurch ⭐️⭐️ https://myaction.app/pHsh0nYiG2b

I.Happ o1.5 Total Bases+165

0.5u

@cowhitchurch ⭐️⭐️ https://myaction.app/pHsh0nYiG2b

Under 8-110

0.5u

@Zerillo ⭐️⭐️ https://myaction.app/pHsh0nYiG2b

M.Boyd o5.5 Ks+145

0.38u

#EV 4.4% FD +118 BO +117

Under 4 (F5)+115

0.58u

#EV 2.67% Pinny +103 Circa +100 BO +100

S.Suzuki o1.5 Hits + Runs + RBIs-106

M.Boyd o15.5 Outs-124

1.24u

SD u3.5-105

1.05u

CHC -110

1.1u

Over 0.5 (1st Inn)+115

0.77u

#EV 6.19% Pinny -105 FD -113

Under 8-105

0.53u

Bet to -115

Under 8-105

1.05u

(DK) 94 PRF, cool temps, forecast historically more suppressive by 7-8% - see notes on F5 – two strong defenses (CHC best) – SDP best bullpen estimators MLB (Would decrease to 0.5u at 7.5)

CHC -128 (F5)

0.64u

(FD) Vasquez has been impressive (19.3 K-BB%), but still 13.5% Barrels/BBE (4.33 xERA), Boyd 2.02 SIERA/3.74 xERA through 3 starts – CHC proj LU 21 pt wRC+ edge v L/RHP since LY, teams separated by 35 points this year – CHC 11 Runs Prevented, proj LU 15 FRV best in MLB – SDP far better pen though, so F5 (Would only play to -135)

SD +100

0.5u

Cubs vs Padres: The Bet To Make in This Close Matchup
Nick Martin•
Apr 27, 2026 UTC

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No props found

MLB Public Betting

Padres are 3-2 in their last 5 games.
Padres are 2-3 in their last 5 games against the spread
Padres are 18-14 in their road games against the spread
The totals have gone OVER in 4 of Padres' last 5 games
The totals have gone OVER in 16 of Padres' 38 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Padres	38-32	20-18	18-14	16-17	22-15
Cubs	27-45	12-23	15-22	17-31	10-14

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Padres	31-38-1	16-21-1	15-17	13-19-1	18-19
Cubs	37-35	18-17	19-18	23-25	14-10

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Padres	37-33	19-19	18-14	18-15	19-18
Cubs	37-35	20-15	17-20	26-22	11-13

date	opponent	score	spread	over/under	moneyline
Apr 26th	@ARI	L 7-12	-1.5 L	O 14.5	ARI -135
Apr 25th	@ARI	W 6-4	-1.5 W	U 16	SD -105
Apr 23rd	@COL	W 10-8	-1.5 W	O 10.5	SD -155
Apr 23rd	@COL	L 3-8	-1.5 L	U 12	COL -161
Apr 22nd	@COL	W 1-0	-1.5 L	U 11	SD -147

Tyler Austin
1B
Austin is out with knee
Out
Justin Steele
SP
Steele is out with elbow
Out

Joe Musgrove
SP
Musgrove is out with elbow
Out

See more MLB Injuries

PITCHER	PC	IP	K	ER
LM.Boyd, P	91	4	4	5
RB.Brown, P	43	2	1	0
RP.Maton, P	28	1	2	2
RJ.Webb, P	15	1	1	1

HITTERS	H-AB	R	HR	RBI
1N.Hoerner, 2B	0-4	0	0	1
2M.Busch, 1B	0-5	0	0	0
3A.Bregman, 3B	0-4	1	0	0
4I.Happ, DH	1-4	1	0	0
5S.Suzuki, RF	2-4	2	1	1
6M.Ballesteros, C	1-4	1	1	4
7M.Conforto, LF	0-2	0	0	0
7M.Shaw, PH	1-2	1	0	0
7M.Shaw, LF	1-2	1	0	0
8D.Swanson, SS	2-3	1	0	0
9P.Crow-Armstrong, CF	1-3	0	0	0

PITCHER	PC	IP	K	ER
RR.Vasquez, P	106	5	4	5
LA.Morejon, P	27	1.2	2	0
RJ.Adam, P	17	1.1	1	0
RM.Miller, P	21	1	1	2

HITTERS	H-AB	R	HR	RBI
1R.Laureano, LF	1-4	1	0	0
2F.Tatis, 2B	2-5	0	0	0
2F.Tatis, RF	2-5	0	0	0
3J.Merrill, CF	1-5	1	0	1
4M.Machado, 3B	3-4	3	0	0
4G.Sheets, 1B	1-1	1	1	1
5X.Bogaerts, SS	2-5	1	0	0
6M.Andujar, DH	1-3	1	0	1
7T.France, 1B	2-3	1	0	4
7T.France, 3B	2-3	1	0	4
8N.Castellanos, RF	1-4	0	0	2
8J.Cronenworth, 2B	0-0	0	0	0
9F.Fermin, C	0-4	0	0	0