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Diamondbacks vs. Astros Odds & Betting Predictions - September 5, 2026

Diamondbacks at Astros

11:15 pm • FOX

Arizona Diamondbacks

74-67
@

Houston Astros

72-69
Starting Pitchers
pitcherteameraw-l
Ethan Pecko logoE.PeckoHouston Astros logo6.231-0
Brandon Pfaadt logoB.PfaadtArizona Diamondbacks logo3.497-2

Diamondbacks at Astros Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Diamondbacks
74-67
+1.5
-1.5+150
o8.5-110
-110
Astros
72-69
u8.5
+1.5-182
u8.5-110
-110
location pinSaturday 11:15 p.m.
September 05, 2026
Daikin ParkHouston
thermometer image87°Fahrenheit
rain image9%Rain
wind image6Wind

Prop Odds Comparison

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No props found

Line Movement Tracker

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Diamondbacks vs. Astros Public Betting Percentages

Away Logo

Diamondbacks

Public

Home Logo

Astros

29%

Bets%

71%

Money%

MLB Public Betting Right Arrow

Betting Trends

  • Astros are 4-1 in their last 5 games.
  • Astros are 4-1 in their last 5 games against the spread
  • Astros are 36-33 in their road games against the spread
  • The totals have gone OVER in 1 of Astros' last 5 games
  • The totals have gone OVER in 38 of Astros' 72 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Astros		70-7134-3836-3323-3545-33
Diamondbacks		76-6541-3135-3428-3247-33

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Astros		70-62-938-32-232-30-731-26-138-32-8
Diamondbacks		61-76-430-40-231-36-226-32-234-44-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Astros		72-6936-3636-3329-2941-37
Diamondbacks		74-6741-3133-3635-2538-42

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 3rdCWSW 6-2-1.5 WU 8.5HOU -170
Sep 3rdCWSW 2-0-1.5 WU 8.5HOU -144
Sep 2ndCWSL 1-5+1.5 LU 8.5CWS -104
Sep 1stCWSW 6-3-1.5 WO 8.5HOU -128
Aug 30th@NYMW 6-3+1.5 WU 9HOU +110

Astros vs. Diamondbacks Injury Updates

Astros Injuries

    Diamondbacks Injuries

    • Corbin Burnes
      SP

      Burnes is out with elbow

      Out

    • Blake Walston
      SP

      Walston is out with elbow

      Out

    • Cristian Mena
      SP

      Mena is doubtful with shoulder

      Doubtful

    See more MLB Injuries Right Arrow
    Diamondbacks vs. Astros Starting Lineups
    Diamondbacks Starting Lineup
    Projected
    PITCHERW-LERAWHIPK/9
    Brandon Pfaadt logoRB.Pfaadt, P7-23.491.1355.92
    HITTERSAVGOBPSLGHR
    Geraldo Perdomo logo1G.Perdomo, SS.253.360.3699
    Corbin Carroll logo2C.Carroll, RF.241.337.47019
    Gabriel Moreno logo3G.Moreno, C.298.376.46011
    Ketel Marte logo4K.Marte, DH.251.317.44421
    Lars Nootbaar logo5L.Nootbaar, LF.224.333.4183
    Nolan Arenado logo6N.Arenado, 3B.234.308.42221
    Tim Tawa logo7T.Tawa, 1B.240.296.3949
    Ildemaro Vargas logo8I.Vargas, 2B.251.293.3849
    Ryan Waldschmidt logo9R.Waldschmidt, CF.273.336.3883
    Astros Starting Lineup
    Projected
    PITCHERW-LERAWHIPK/9
    Ethan Pecko logoRE.Pecko, P1-06.231.5386.23
    HITTERSAVGOBPSLGHR
    Jeremy Pena logo1J.Pena, SS.278.332.46917
    Yordan Alvarez logo2Y.Alvarez, DH.316.433.60237
    Isaac Paredes logo3I.Paredes, 3B.257.357.42218
    Jose Altuve logo4J.Altuve, 2B.244.309.39715
    Daulton Varsho logo5D.Varsho, CF.243.307.3757
    Christian Walker logo6C.Walker, 1B.228.302.42624
    Taylor Trammell logo7T.Trammell, RF.209.295.3657
    Yainer Diaz logo8Y.Diaz, C.257.287.41410
    LaMonte Wade logo9L.Wade, LF.208.323.3403

    Diamondbacks vs. Astros Odds Comparison

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    Diamondbacks at Astros Team Totals

    MatchupOverUnder
    Diamondbacks
    74-67
    N/A
    N/A
    Astros
    72-69
    N/A
    N/A