The Houston Astros host the Arizona Diamondbacks on September 5, 2026. First pitch from Daikin Park is scheduled for 7:15 p.m. EDT. The game will be broadcast on FOX.
The Diamondbacks are favored by -110 on the moneyline and by -1.5 on the run line. The Astros are -110 on the moneyline and +1.5 on the run line. The total is set at 8.5 runs.
Find my MLB picks and Diamondbacks vs Astros prediction below, as well as probable pitchers, weather report, and more.
Diamondbacks vs Astros Prediction
- Diamondbacks vs Astros Pick: Brandon Pfaadt Under 4.5 Strikeouts (-125)
My Diamondbacks vs Astros best bet is on Pfaadt to record under 4.5 strikeouts. Make sure to find the best odds by checking our live MLB odds page.
Diamondbacks vs Astros Odds
| Diamondbacks Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 -182 | 8.5 -110o / -110u | -110 |
| Astros Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 +150 | 8.5 -110o / -110u | -110 |
- Diamondbacks vs Astros moneyline: Diamondbacks -110, Astros -110
- Diamondbacks vs Astros over/under: 8.5 (-110o / -110u)
- Diamondbacks vs Astros spread: Diamondbacks -1.5 (+150), Astros +1.5 (-182)
Diamondbacks vs Astros Probable Pitchers
| Brandon Pfaadt | Stat | Ethan Pecko |
|---|---|---|
| 7-2 | W-L | 1-0 |
| 1.3 | fWAR (FanGraphs) | -0.3 |
| 3.49 / 3.78 | ERA / xERA | 6.23 / 7.31 |
| 4.17 / 4.39 | FIP / xFIP | 8.02 / 6.33 |
| 10.1 | K-BB% | 0 |
| 47.1 | GB% | 30.8 |
| .255 | BABIP | .200 |
| 94 | Stuff+ | 101 |
| 105 | Location+ | 91 |
Diamondbacks vs Astros MLB Betting Preview
Diamondbacks vs Astros Pick, Betting Analysis
By Prop Model
The strikeouts prop for Brandon Pfaadt looks like a strong wager based on the current data. The line of 4.5 compares favorably based on our MLB simulations. The prop projects to hit 64.47% of the time based on the assumptions, and that represents a 9.32% edge.
You can find all prop bet evaluations in ParlayIQ.
Pick: Brandon Pfaadt Under 4.5 Strikeouts (-125)
