Guardians vs. Red Sox Odds & Betting Predictions - September 23, 2026
Guardians at Red Sox
11:10 pm • ESPNStarting Pitchers
| pitcher | team | era | w-l | |
|---|---|---|---|---|
![]() | 2.72 | 18-5 | ||
![]() | 5.19 | 3-3 |
Guardians at Red Sox Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Guardians 5-6 | +1.5 | +1.5-199 | o6.5-114 | +119 |
Red Sox 0-2 | u7.5 | -1.5+163 | u6.5-104 | -142 |

Fenway ParkBoston
Guardians vs. Red Sox Expert Picks
Mike McNamara
Last 30d: 80-57-1 (+10.4u)
BOS -136
0.2u
Doug Ziefel
Last 30d: 411-345-10 (+42.8u)
F.Griffin o4.5 Ks+102
0.5u
J.Jones u0.5 Hits+120
0.42u
The Degenerates
Last 30d: 74-69-1 (-2.1u)
Under 3.5 (F5)-110
1u
Brian Bitler
Last 30d: 70-80-1 (-27.7u)
CLE +120
3u
Austin Pendergrass
Last 30d: 82-62-0 (+5.5u)
Under 0.5 (1st Inn)-146
0.34u
Topper
Last 30d: 115-105-2 (-22.7u)
Under 6.5+100
1u
Wind In Good Home Pitcher (***)
Overall: 268-157-12,63% (ROI:21%)
Season:11-2-1,85% (ROI:57%)
Late szn Non Division Under Streak
Overall: 125-54-6,70% (ROI:34%)
Season:0-0-0, 0% (ROI: 0%)
#TSA
Adam Kaufman
Last 30d: 334-306-16 (-15.2u)
CLE +114
1u
Derek Carty
Last 30d: 25-19-0 (+14.2u)
J.Jones u0.5 Hits+130
1u
There is a value opportunity on Jahmai Jones's hits prop. THE BAT X is projecting him to record 0.64 hits, while oddsmakers are implying 0.80. The model believes there is a 53% chance he records fewer than 1 hit, so there is value on the under at +130. This play is good down to at least +109.
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Guardians vs. Red Sox Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Guardians vs. Red Sox Public Betting Percentages
Betting Trends
- Red Sox are 3-2 in their last 5 games.
- Red Sox are 2-3 in their last 5 games against the spread
- Red Sox are 41-40 in their road games against the spread
- The totals have gone OVER in 1 of Red Sox' last 5 games
- The totals have gone OVER in 35 of Red Sox' 80 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Red Sox vs. Guardians Injury Updates

Red Sox Injuries
- Tanner HouckSP
Houck is out with arm
Out
- Triston Casas1B
Casas is out with knee
Out
- Kutter CrawfordSP
Crawford is out with wrist
Out

Guardians Injuries
Guardians vs. Red Sox Box Score
Guardians Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 83 | 6 | 7 | 1 | |
![]() | 21 | 1 | 3 | 0 | |
![]() | 14 | 0.2 | 0 | 0 | |
![]() | 1 | 0.1 | 0 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 2-4 | 0 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 0-2 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 1-3 | 0 | 0 | 0 |
![]() | 1-3 | 0 | 0 | 0 |
![]() | 1-3 | 0 | 0 | 0 |
Red Sox Player Stats| PITCHER | PC | IP | K | ER | |
|---|---|---|---|---|---|
![]() | 77 | 6 | 3 | 0 | |
![]() | 22 | 1 | 3 | 0 | |
![]() | 20 | 1 | 0 | 0 | |
![]() | 12 | 1 | 3 | 0 |
| HITTERS | H-AB | R | HR | RBI |
|---|---|---|---|---|
![]() | 1-4 | 0 | 0 | 0 |
![]() | 2-4 | 0 | 0 | 0 |
![]() | 2-4 | 0 | 0 | 0 |
![]() | 2-4 | 0 | 0 | 0 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 1-1 | 0 | 0 | 0 |
![]() | 2-3 | 1 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 1-3 | 0 | 0 | 1 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 0-0 | 0 | 0 | 0 |
Guardians vs. Red Sox Odds Comparison
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Guardians at Red Sox Team Totals
MatchupOverUnder | ||
|---|---|---|
Guardians 5-6 | N/A | N/A |
Red Sox 0-2 | N/A | N/A |
































