Guardians vs Red Sox Odds: Moneyline, Over/Under, Props - September 22, 2026 | The Action Network

Guardians at Red Sox

10:45 pm • CLEG

Cleveland Guardians

@

Boston Red Sox

pitcher		team	era	w-l
J.Bennett			0.00	0-0
F.Griffin			0.00	0-0

MatchupOpenSpreadTotalMoneyline
Guardians 79-75	N/A	N/A	N/A
Red Sox 84-70	N/A	N/A	N/A

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Tuesday 10:45 p.m.

September 22, 2026

Fenway ParkBoston

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58°Fahrenheit

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0%Rain

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9Wind

No props found

MLB Public Betting

Red Sox are 3-2 in their last 5 games.
Red Sox are 2-3 in their last 5 games against the spread
Red Sox are 40-39 in their road games against the spread
The totals have gone OVER in 1 of Red Sox' last 5 games
The totals have gone OVER in 34 of Red Sox' 75 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Red Sox	73-81	33-42	40-39	48-61	24-20
Guardians	74-80	35-44	39-36	40-54	34-22

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Red Sox	70-80-4	34-38-3	36-42-1	51-55-3	19-24-1
Guardians	74-80	41-38	33-42	45-49	27-29

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Red Sox	84-70	38-37	46-33	60-49	23-21
Guardians	79-75	39-40	40-35	51-43	28-28

date	opponent	score	spread	over/under	moneyline
Sep 19th	@TB	L 1-2	+1.5 W	U 7.5	TB +125
Sep 18th	@TB	W 4-2	+1.5 W	U 7.5	BOS +114
Sep 18th	@TEX	W 4-3	-1.5 L	U 8	BOS -130
Sep 17th	@TEX	L 3-7	-1.5 L	O 8	TEX -112
Sep 16th	@TEX	L 2-4	+1.5 L	U 7.5	TEX +124

Tanner Houck
SP
Houck is out with arm
Out
Triston Casas
1B
Casas is out with knee
Out
Kutter Crawford
SP
Crawford is out with wrist
Out

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MatchupOverUnder
Guardians 79-75	N/A	N/A
Red Sox 84-70	N/A	N/A