Guardians vs. White Sox Odds & Betting Predictions - June 22, 2026

Guardians at White Sox

11:40 pm • CHSN

Cleveland Guardians

@

Chicago White Sox

pitcher		team	era	w-l
A.Kay			4.61	6-2
G.Williams			3.83	9-4

MatchupOpenSpreadTotalMoneyline
Guardians 41-37	-1.5	-1.5+145	o7.5-121	-115
White Sox 39-37	u7.5	+1.5-175	u7.5+100	-105

location pin

Monday 11:40 p.m.

June 22, 2026

Rate FieldChicago

thermometer image

67°Fahrenheit

rain image

0%Rain

wind image

9Wind

CLE -115

1.15u

Opening Pitch: Zerillo’s MLB Projections for Monday
Sean Zerillo•
Jun 20, 2026 UTC

See more MLB Coverage

No props found

MLB Public Betting

White Sox are 1-4 in their last 5 games.
White Sox are 2-3 in their last 5 games against the spread
White Sox are 19-21 in their road games against the spread
The totals have gone OVER in 2 of White Sox' last 5 games
The totals have gone OVER in 20 of White Sox' 36 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
White Sox	43-33	24-12	19-21	7-5	36-28
Guardians	42-36	19-17	23-19	18-23	24-13

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
White Sox	44-31-1	20-15-1	24-16	6-5-1	38-26
Guardians	38-40	18-18	20-22	21-20	17-20

Straight-Up (ML) History

	overall	home	away	favorite	underdog
White Sox	39-37	24-12	15-25	8-4	31-33
Guardians	41-37	19-17	22-20	22-19	19-18

date	opponent	score	spread	over/under	moneyline
Jun 21st	@DET	L 4-5	-1.5 L	O 8.5	DET +100
Jun 20th	@DET	L 1-4	+1.5 L	U 9	DET +104
Jun 19th	@DET	L 3-4	+1.5 W	U 8.5	DET +168
Jun 18th	@NYY	W 5-1	+1.5 W	U 10	CWS +145
Jun 17th	@NYY	L 5-10	+1.5 L	O 8.5	NYY +148

Mike Vasil
P
Vasil is out with elbow
Out
Ky Bush
P
Bush is out with elbow
Out
Brooks Baldwin
OF
Baldwin is out with elbow
Out
Kyle Teel
C
Teel is out with hamstring
Out
Drew Thorpe
P
Thorpe is out with elbow
Out

See more MLB Injuries

PITCHER		W-L	ERA	WHIP	K/9
RG.Williams, P		9-4	3.83	1.135	10.11

HITTERS	AVG	OBP	SLG	HR
1T.Bazzana, 2B	.273	.367	.471	7
2D.Fry, RF	.223	.339	.379	4
3B.Rocchio, SS	.268	.346	.390	5
4R.Hoskins, DH	.174	.311	.360	7
5K.Manzardo, 1B	.238	.326	.410	9
6G.Arias, 3B	.213	.245	.383	2
7S.Fairchild, CF	.188	.458	.188	0
8S.Kwan, LF	.206	.316	.251	1
9A.Hedges, C	.260	.324	.350	1

PITCHER		W-L	ERA	WHIP	K/9
LA.Kay, P		6-2	4.61	1.436	7.04

HITTERS	AVG	OBP	SLG	HR
1S.Antonacci, LF	.287	.386	.421	4
2M.Vargas, 3B	.236	.353	.465	16
3A.Benintendi, DH	.234	.292	.425	9
4C.Montgomery, SS	.221	.316	.494	20
5C.Meidroth, 2B	.271	.338	.386	6
6B.Montgomery, RF	.231	.268	.385	1
7J.Gonzalez, 1B	.167	.273	.229	1
8T.Peters, CF	.289	.352	.442	3
9D.Romo, C	.144	.235	.356	5

Could not load odds

See more MLB Odds

MatchupOverUnder
Guardians 41-37	N/A	N/A
White Sox 39-37	N/A	N/A