Red Sox vs. Astros Odds & Betting Predictions - April 1, 2026

Red Sox at Astros

6:10 pm • NESN

Boston Red Sox

18-25

4 - 6

Houston Astros

17-28

pitcher		team	era	w-l
M.Burrows			5.04	2-4
G.Crochet			6.30	3-3

MatchupOpenSpreadTotalMoneyline
Red Sox 18-25	-1.5	-1.5+127	o7-115	-152
Astros 17-28	u7.5	+1.5-148	u7-106	+127

Wednesday 6:10 p.m.

April 01, 2026

Daikin ParkHouston

R.Anthony o1.5 Hits + Runs + RBIs-110

$1.10

BOS o3.5-135

Over 7.5+115

1.15u

BOS -150

$15.00

READ HERE —> https://www.actionnetwork.com/mlb/boston-red-sox-vs-houston-astros-prediction-pick-odds-mlb-wednesday-april-1

W.Abreu o1.5 Hits + Runs + RBIs-102

BOS -150

$1.50

M.Burrows o5.5 Ks-106

BOS -137

0.45u

Bet to -150. Split with F5.

BOS -156 (F5)

0.51u

Bet to -165

HOU +124

1.24u

Zerillo's Pick for Red Sox vs Astros
Sean Zerillo•
Apr 1, 2026 UTC
Zerillo's Opening Pitch for Wednesday
Sean Zerillo•
Apr 1, 2026 UTC

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No props found

MLB Public Betting

Astros are 1-4 in their last 5 games.
Astros are 1-4 in their last 5 games against the spread
Astros are 8-14 in their road games against the spread
The totals have gone OVER in 1 of Astros' last 5 games
The totals have gone OVER in 15 of Astros' 22 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Astros	17-27	9-13	8-14	4-11	13-15
Red Sox	16-26	7-14	9-12	10-18	5-8

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Astros	26-16-2	15-7	11-9-2	9-6	16-10-2
Red Sox	19-22-1	5-15-1	14-7	12-15-1	7-6

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Astros	17-27	10-12	7-15	5-10	12-16
Red Sox	18-24	8-13	10-11	13-15	4-9

date	opponent	score	spread	over/under	moneyline
Apr 1st	BOS	W 9-2	-1.5 W	O 7.5	HOU -146
Mar 31st	BOS	W 8-1	+1.5 W	O 8.5	HOU +113
Mar 29th	LAA	W 9-7	-1.5 W	O 9	HOU -170
Mar 28th	LAA	W 11-9	-1.5 W	O 8.5	HOU -135
Mar 28th	LAA	L 2-6	-1.5 L	U 8.5	LAA -172

Tanner Houck
SP
Houck is out with arm
Out
Triston Casas
1B
Casas is out with knee
Out
Patrick Sandoval
SP
Sandoval is out with elbow
Out
Kutter Crawford
SP
Crawford is out with wrist
Out
Romy Gonzalez
1B
Gonzalez is out with shoulder
Out

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PITCHER	PC	IP	K	ER
LG.Crochet, P	93	5	7	4
RG.Weissert, P	16	1	1	0
LD.Coulombe, P	16	1	0	1
RG.Whitlock, P	37	1	1	0

HITTERS	H-AB	R	HR	RBI
1J.Duran, LF	1-5	1	0	1
2T.Story, SS	0-5	0	0	0
3M.Yoshida, DH	0-3	0	0	0
4W.Contreras, 1B	1-3	0	0	1
5W.Abreu, RF	2-4	1	1	1
6C.Durbin, 3B	0-4	0	0	0
7C.Rafaela, CF	0-3	0	0	0
8I.Kiner-Falefa, 2B	0-2	1	0	0
8R.Anthony, PH	1-1	1	1	1
9C.Wong, C	2-3	0	0	0
9M.Mayer, PH	0-1	0	0	0

PITCHER	PC	IP	K	ER
RM.Burrows, P	84	5	6	2
RA.Blubaugh, P	14	1	1	0
LB.King, P	12	1	2	0
RK.Teng, P	14	1	1	1
RB.Abreu, P	16	1	3	1

HITTERS	H-AB	R	HR	RBI
1J.Altuve, 2B	1-4	1	0	0
2Y.Alvarez, DH	2-3	2	0	0
3I.Paredes, 3B	1-3	1	0	1
4C.Correa, SS	1-4	1	1	3
5C.Walker, 1B	1-4	0	0	1
6C.Smith, RF	1-4	0	0	0
7J.Meyers, CF	0-3	0	0	0
8B.Matthews, LF	0-3	0	0	0
8J.Loperfido, PH	0-0	0	0	0
8J.Loperfido, LF	0-0	0	0	0
9C.Vazquez, C	1-4	1	1	1