Reds vs. Guardians Odds & Betting Predictions - March 22, 2026

Reds at Guardians

7:05 pm • CINR

Cincinnati Reds

2

2 - 8

Cleveland Guardians

8

pitcher		team	era	w-l
G.Williams			5.68	1-1
N.Lodolo			5.93	1-1

MatchupOpenSpreadTotalMoneyline
Reds 14-15	+1.5	+1.5-175	o11-108	+102
Guardians 14-14	u11.5	-1.5+145	u11-110	-122

location pin

Sunday 7:05 p.m.

March 22, 2026

Goodyear BallparkGoodyear

Over 11-108

1.25u

No props found

MLB Public Betting

Guardians are 3-2 in their last 5 games.
Guardians are 1-4 in their last 5 games against the spread
Guardians are 47-34 in their road games against the spread
The totals have gone OVER in 2 of Guardians' last 5 games
The totals have gone OVER in 37 of Guardians' 81 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Guardians	86-76	39-42	47-34	33-36	51-38
Reds	82-78	40-39	42-39	29-43	53-34

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Guardians	69-87-6	37-41-3	32-46-3	34-34-1	34-50-5
Reds	58-91-11	26-45-8	32-46-3	20-47-5	37-44-6

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Guardians	88-74	45-36	43-38	44-25	43-46
Reds	83-79	44-35	38-43	39-33	43-44

date	opponent	score	spread	over/under	moneyline
Mar 21st	@SF	L 7-10	+1.5 L	O 11.5	SF +136
Mar 21st	SEA	L 8-20	+1.5 L	O 12	SEA -110
Mar 20th	KC	W 6-5	-	-	-
Mar 18th	@CIN	W 8-6	+1.5 W	O 11.5	CLE +114
Mar 17th	CHC	L 2-5	-1.5 L	U 9.5	CHC -120

Noelvi Marte
RF
Marte is day-to-day with side
Day-to-Day
Brandon Williamson
SP
Williamson is out for season with elbow
Out for Season
Graham Ashcraft
RP
Ashcraft is out with groin
Out
Chase Burns
SP
Burns is out with hip
Out
Julian Aguiar
SP
Aguiar is out for season with elbow
Out for Season
Rhett Lowder
SP
Lowder is out with elbow
Out

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PITCHER		PC	IP	K	ER
LN.Lodolo, P		10	0	0	2
RG.Ashcraft, P		20	1	1	1
RC.Phillips, P		16	1	1	0
RL.Mey, P		23	1	1	0
LK.McCoy, P		21	1	2	0

HITTERS	H-AB	R	HR	RBI
1W.Benson, LF	1-3	0	0	0
1K.Vu, LF	0-2	0	0	0
2S.Steer, 2B	0-3	0	0	0
2A.Vargas, 2B	1-1	1	0	0
3S.Stewart, DH	0-3	0	0	0
3R. Ibarra, PH	1-1	0	0	0
3R. Ibarra, DH	1-1	0	0	0
4N.Lowe, 1B	0-3	0	0	0
4Z.Warren, 1B	1-1	0	0	1
5T.Stephenson, C	1-2	0	0	0
5W.Banfield, C	1-2	0	0	0
6N.Marte, RF	2-2	1	1	1
6C. Jorge, RF	1-2	0	0	0
6C. Jorge, CF	1-2	0	0	0
7D.Myers, CF	0-3	0	0	0
7Y. Confidan, RF	0-1	0	0	0
8P.Higgins, 3B	0-2	0	0	0
9G.Hampson, SS	1-2	0	0	0
9C. Sanchez, SS	0-2	0	0	0

PITCHER		PC	IP	K	ER
RG.Williams, P		64	5	3	1
RM.Festa, P		22	1.1	1	0
LE.Sabrowski, P		10	0.2	1	0
RC.Brogdon, P		21	1	2	1
LK.Allard, P		13	1	1	0

HITTERS	H-AB	R	HR	RBI
1S.Kwan, CF	0-2	2	0	0
2A.Martinez, LF	1-3	1	1	2
2J. Benjamin, 3B	1-2	1	0	0
3J.Ramirez, 3B	1-2	1	0	0
3S.Fairchild, CF	1-2	0	0	0
4R.Hoskins, 1B	1-3	1	0	1
4D.Nunez, C	0-1	0	0	0
5C.DeLauter, RF	2-2	0	0	2
5M. Collado, 1B	0-2	0	0	0
6G.Arias, SS	0-3	0	0	0
7B.Naylor, C	1-3	0	0	1
8K.Manzardo, DH	1-3	1	1	1
9B.Rocchio, 2B	1-2	1	0	0

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MatchupOverUnder
Reds 14-15	N/A	N/A
Guardians 14-14	N/A	N/A