White Sox vs. Cubs Odds & Betting Predictions - May 18, 2025

White Sox at Cubs

6:20 pm • MARQ

Chicago White Sox

38-66

2 - 6

Chicago Cubs

60-43

pitcher		team	era	w-l
C.Rea			4.06	8-4
J.Cannon			4.48	4-7

MatchupOpenSpreadTotalMoneyline
White Sox 38-66	+1.5	+1.5+100	o7.5-111	+217
Cubs 60-43	u8	-1.5-118	u7.5-110	-267

Sunday 6:20 p.m.

May 18, 2025

Wrigley FieldChicago

Under 7.5-110

1.1u

*Windy* Overall: 1116-765-85,59% (ROI:14%) Season:17-13-1,57% (ROI:9%)

Under 8-118

1.18u

CWS +1.5+115

Cubs chasing sweep, but White Sox got their stopper on the mound. Cannon just blanked the Reds over 6 IP, now brings a 3.60 ERA and 88.8 EV-against into Wrigley. His cutter/sinker/slider mix keeps hitters off balance. Cubs won 2 straight, but rivalry games get weird. Rea’s ERA says dominant (2.48), but xwOBA (.319) and xBA (.262) say otherwise. K-rate only 19.6% – Sox can put balls in play. Meidroth hitting .450 last 5, just went deep. Vaughn/Robert Jr. still dangerous – both top 50 in Hard Hit%. Cubs’ bullpen sharp lately (2.63 ERA last 3), but Sox can avoid it if Cannon eats innings. No fear of sweep = more freedom at the plate. Rivalry + motivation = tight game feels likely.

Under 8-115

0.58u

Bet to 7.5 (+100)

No props found

MLB Public Betting

Cubs are 1-4 in their last 5 games.
Cubs are 1-4 in their last 5 games against the spread
Cubs are 26-25 in their road games against the spread
The totals have gone OVER in 4 of Cubs' last 5 games
The totals have gone OVER in 28 of Cubs' 52 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Cubs	51-52	25-27	26-25	38-33	13-19
White Sox	60-44	29-22	31-22	0-2	60-42

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Cubs	52-46-5	28-22-2	24-24-3	35-33-3	17-13-2
White Sox	46-54-4	27-21-3	19-33-1	0-2	46-52-4

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Cubs	60-43	33-19	27-24	48-23	12-20
White Sox	38-66	22-29	16-37	1-1	37-65

date	opponent	score	spread	over/under	moneyline
May 17th	CWS	W 7-3	-1.5 W	U 10	CHC -322
May 16th	CWS	W 13-3	-1.5 W	O 11.5	CHC -231
May 14th	MIA	L 1-3	-1.5 L	U 7.5	MIA -218
May 13th	MIA	W 5-4	-1.5 L	O 8	CHC -262
May 12th	MIA	W 5-2	-1.5 W	U 8	CHC -257

Ryan Noda
1B
Noda is out with quad
Out
Ky Bush
SP
Bush is out with elbow
Out
Drew Thorpe
SP
Thorpe is out with elbow
Out
Shane Smith
SP
Smith is out with ankle
Out

Jameson Taillon
SP
Taillon is out with calf
Out
Justin Steele
SP
Steele is out for season with elbow
Out for Season

See more MLB Injuries

PITCHER	PC	IP	K	ER
RJ.Cannon, P	88	5	3	3
RS.Wilson, P	16	1	1	0
LB.Eisert, P	15	0.2	2	1
RM.Castro, P	26	1.1	0	1

HITTERS	H-AB	R	HR	RBI
1C.Meidroth, SS	1-4	0	0	0
2M.Vargas, 3B	2-3	1	1	1
3J.Palacios, DH	0-2	0	0	0
3A.Vaughn, PH	0-2	0	0	0
3A.Vaughn, DH	0-2	0	0	0
4L.Robert, CF	2-4	1	0	0
5J.Rojas, 2B	0-2	0	0	0
5L.Sosa, PH	1-2	0	0	0
5L.Sosa, 2B	1-2	0	0	0
6E.Quero, C	1-3	0	0	1
7T.Elko, 1B	1-4	0	0	0
8B.Baldwin, LF	0-3	0	0	0
9M.Taylor, RF	0-3	0	0	0

PITCHER	PC	IP	K	ER
RC.Rea, P	93	5.1	3	1
LD.Pomeranz, P	6	0.2	1	0
RR.Pressly, P	9	1	0	0
RB.Keller, P	12	1	1	0
RJ.Merryweather, P	14	1	1	1

HITTERS	H-AB	R	RBI
1P.Crow-Armstrong, CF	2-4	2	0
2K.Tucker, RF	1-4	1	0
3S.Suzuki, LF	0-1	0	2
4M.Busch, 1B	2-4	0	1
5C.Kelly, C	0-4	0	0
6D.Swanson, SS	1-4	1	0
7M.Ballesteros, DH	0-2	0	0
7J.Turner, PH	0-2	0	0
7J.Turner, DH	0-2	0	0
8N.Hoerner, 2B	2-4	1	1
9V.Brujan, 3B	2-3	1	1
9N.Lopez, 3B	0-1	0	0