White Sox vs. Cubs Odds & Betting Predictions - May 18, 2025
White Sox at Cubs
6:20 pm • MARQStarting Pitchers
pitcher | team | era | w-l | |
---|---|---|---|---|
![]() | ![]() | 2.48 | 3-0 | |
![]() | ![]() | 3.60 | 2-4 |
White Sox at Cubs Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
---|---|---|---|---|
![]() White Sox 14-32 | +1.5 | +1.5+100 | o7.5-111 | +217 |
![]() Cubs 27-19 | u8 | -1.5-118 | u7.5-110 | -267 |

Wrigley FieldChicago
White Sox vs. Cubs Expert Picks

Top Shelf Action 🥃
Last 30d: 337-547-15 (-12.7u)
Under 7.5-110
1.1u
*Windy*
Overall: 1116-765-85,59% (ROI:14%)
Season:17-13-1,57% (ROI:9%)

Bet Labs
Last 30d: 34-32-1 (-2.6u)
Under 8-118
1.18u

Picks Office
Last 30d: 73-91-4 (-24.4u)
CWS +1.5+115
1u
Cubs chasing sweep, but White Sox got their stopper on the mound. Cannon just blanked the Reds over 6 IP, now brings a 3.60 ERA and 88.8 EV-against into Wrigley. His cutter/sinker/slider mix keeps hitters off balance. Cubs won 2 straight, but rivalry games get weird.
Rea’s ERA says dominant (2.48), but xwOBA (.319) and xBA (.262) say otherwise. K-rate only 19.6% – Sox can put balls in play. Meidroth hitting .450 last 5, just went deep. Vaughn/Robert Jr. still dangerous – both top 50 in Hard Hit%.
Cubs’ bullpen sharp lately (2.63 ERA last 3), but Sox can avoid it if Cannon eats innings. No fear of sweep = more freedom at the plate. Rivalry + motivation = tight game feels likely.

Sean Zerillo
Last 30d: 150-167-9 (-8.8u)
Under 8-115
0.58u
Bet to 7.5 (+100)
Prop Odds Comparison
Line Movement Tracker
White Sox vs. Cubs Public Betting Percentages
Betting Trends
- Cubs are 4-1 in their last 5 games.
- Cubs are 3-2 in their last 5 games against the spread
- Cubs are 12-10 in their road games against the spread
- The totals have gone OVER in 2 of Cubs' last 5 games
- The totals have gone OVER in 15 of Cubs' 24 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
White Sox vs. Cubs Injury Updates

White Sox Injuries
- Ky BushSP
Bush is out with elbow
Out
- Chase MeidrothSS
Meidroth is day-to-day with thumb
Day-to-Day
- Drew ThorpeSP
Thorpe is out with elbow
Out

Cubs Injuries
- Drew PomeranzRP
Pomeranz is out with elbow
Out
- Justin SteeleSP
Steele is out for season with elbow
Out for Season
White Sox vs. Cubs Box Score

PITCHER | PC | IP | K | ER | |
---|---|---|---|---|---|
![]() | 88 | 5 | 3 | 3 | |
![]() | 16 | 1 | 1 | 0 | |
![]() | 15 | 0.2 | 2 | 1 | |
![]() | 26 | 1.1 | 0 | 1 |
HITTERS | H-AB | R | HR | RBI |
---|---|---|---|---|
![]() | 1-4 | 0 | 0 | 0 |
![]() | 2-3 | 1 | 1 | 1 |
![]() | 0-2 | 0 | 0 | 0 |
![]() | 0-2 | 0 | 0 | 0 |
![]() | 0-2 | 0 | 0 | 0 |
![]() | 2-4 | 1 | 0 | 0 |
![]() | 0-2 | 0 | 0 | 0 |
![]() | 1-2 | 0 | 0 | 0 |
![]() | 1-2 | 0 | 0 | 0 |
![]() | 1-3 | 0 | 0 | 1 |
![]() | 1-4 | 0 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |

PITCHER | PC | IP | K | ER | |
---|---|---|---|---|---|
![]() | 93 | 5.1 | 3 | 1 | |
![]() | 6 | 0.2 | 1 | 0 | |
![]() | 9 | 1 | 0 | 0 | |
![]() | 12 | 1 | 1 | 0 | |
![]() | 14 | 1 | 1 | 1 |
HITTERS | H-AB | R | HR | RBI |
---|---|---|---|---|
![]() | 2-4 | 2 | 0 | 0 |
![]() | 1-4 | 1 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 2 |
![]() | 2-4 | 0 | 0 | 1 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 1-4 | 1 | 0 | 0 |
![]() | 0-2 | 0 | 0 | 0 |
![]() | 0-2 | 0 | 0 | 0 |
![]() | 0-2 | 0 | 0 | 0 |
![]() | 2-4 | 1 | 0 | 1 |
![]() | 2-3 | 1 | 0 | 1 |
![]() | 0-1 | 0 | 0 | 0 |
White Sox vs. Cubs Odds Comparison
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White Sox at Cubs Team Totals
MatchupOverUnder | ||
---|---|---|
![]() White Sox 14-32 | N/A | N/A |
![]() Cubs 27-19 | N/A | N/A |