White Sox vs. Cubs Odds & Betting Predictions - May 18, 2025

White Sox at Cubs

6:20 pm • MARQ
2 - 6
Starting Pitchers
pitcherteameraw-l
Colin Rea logoC.ReaChicago Cubs logo2.483-0
Jonathan Cannon logoJ.CannonChicago White Sox logo3.602-4

White Sox at Cubs Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
White Sox
14-32
+1.5
+1.5+100
o7.5-111
+217
Cubs
27-19
u8
-1.5-118
u7.5-110
-267
location pinSunday 6:20 p.m.
May 18, 2025
Wrigley FieldChicago
White Sox vs. Cubs Expert Picks
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 337-547-15 (-12.7u)
Under 7.5-110
1.1u
*Windy* Overall: 1116-765-85,59% (ROI:14%) Season:17-13-1,57% (ROI:9%)
Bet Labs
Bet Labs
Last 30d: 34-32-1 (-2.6u)
Under 8-118
1.18u
Picks Office
Picks Office
Last 30d: 73-91-4 (-24.4u)
CWS +1.5+115
1u
Cubs chasing sweep, but White Sox got their stopper on the mound. Cannon just blanked the Reds over 6 IP, now brings a 3.60 ERA and 88.8 EV-against into Wrigley. His cutter/sinker/slider mix keeps hitters off balance. Cubs won 2 straight, but rivalry games get weird. Rea’s ERA says dominant (2.48), but xwOBA (.319) and xBA (.262) say otherwise. K-rate only 19.6% – Sox can put balls in play. Meidroth hitting .450 last 5, just went deep. Vaughn/Robert Jr. still dangerous – both top 50 in Hard Hit%. Cubs’ bullpen sharp lately (2.63 ERA last 3), but Sox can avoid it if Cannon eats innings. No fear of sweep = more freedom at the plate. Rivalry + motivation = tight game feels likely.
Sean Zerillo
Sean Zerillo
Last 30d: 150-167-9 (-8.8u)
Under 8-115
0.58u
Bet to 7.5 (+100)

Prop Odds Comparison

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Line Movement Tracker

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White Sox vs. Cubs Public Betting Percentages

Away Logo

White Sox

Public

8%

Bets%

92%

Money%

MLB Public Betting Right Arrow

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Cubs
24-2212-1212-1015-129-10
White Sox
24-2211-1013-12N/A24-22

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Cubs
26-17-315-8-111-9-214-11-212-6-1
White Sox
20-23-311-8-29-15-1N/A20-23-3

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Cubs
27-1914-1013-918-99-10
White Sox
14-329-125-20N/A14-32

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 17thCWSW 7-3-1.5 WU 10CHC -322
May 16thCWSW 13-3-1.5 WO 11.5CHC -231
May 14thMIAL 1-3-1.5 LU 7.5MIA -218
May 13thMIAW 5-4-1.5 LO 8CHC -262
May 12thMIAW 5-2-1.5 WU 8CHC -257

White Sox vs. Cubs Injury Updates

White Sox Injuries

  • Ky Bush
    SP

    Bush is out with elbow

    Out

  • Chase Meidroth
    SS

    Meidroth is day-to-day with thumb

    Day-to-Day

  • Drew Thorpe
    SP

    Thorpe is out with elbow

    Out

Cubs Injuries

  • Drew Pomeranz
    RP

    Pomeranz is out with elbow

    Out

  • Justin Steele
    SP

    Steele is out for season with elbow

    Out for Season

White Sox vs. Cubs Box Score
White Sox Player Stats
Projected
PITCHERPCIPKER
Jonathan Cannon logoRJ.Cannon, P88533
Steven Wilson logoRS.Wilson, P16110
Brandon Eisert logoLB.Eisert, P150.221
Miguel Castro logoRM.Castro, P261.101
HITTERSH-ABRHRRBI
Chase Meidroth logo1C.Meidroth, SS1-4000
Miguel Vargas logo2M.Vargas, 3B2-3111
Joshua Palacios logo3J.Palacios, DH0-2000
Andrew Vaughn logo3A.Vaughn, PH0-2000
Andrew Vaughn logo3A.Vaughn, DH0-2000
Luis Robert logo4L.Robert, CF2-4100
Josh Rojas logo5J.Rojas, 2B0-2000
Lenyn Sosa logo5L.Sosa, PH1-2000
Lenyn Sosa logo5L.Sosa, 2B1-2000
Edgar Quero logo6E.Quero, C1-3001
Tim Elko logo7T.Elko, 1B1-4000
Brooks Baldwin logo8B.Baldwin, LF0-3000
Michael A. Taylor logo9M.Taylor, RF0-3000
Cubs Player Stats
Projected
PITCHERPCIPKER
Colin Rea logoRC.Rea, P935.131
Drew Pomeranz logoLD.Pomeranz, P60.210
Ryan Pressly logoRR.Pressly, P9100
Brad Keller logoRB.Keller, P12110
Julian Merryweather logoRJ.Merryweather, P14111
HITTERSH-ABRHRRBI
Pete Crow-Armstrong logo1P.Crow-Armstrong, CF2-4200
Kyle Tucker logo2K.Tucker, RF1-4100
Seiya Suzuki logo3S.Suzuki, LF0-1002
Michael Busch logo4M.Busch, 1B2-4001
Carson Kelly logo5C.Kelly, C0-4000
Dansby Swanson logo6D.Swanson, SS1-4100
Moises Ballesteros logo7M.Ballesteros, DH0-2000
Justin Turner logo7J.Turner, PH0-2000
Justin Turner logo7J.Turner, DH0-2000
Nico Hoerner logo8N.Hoerner, 2B2-4101
Vidal Brujan logo9V.Brujan, 3B2-3101
Nicky Lopez logo9N.Lopez, 3B0-1000

White Sox vs. Cubs Odds Comparison

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White Sox at Cubs Team Totals

MatchupOverUnder
White Sox
14-32
N/A
N/A
Cubs
27-19
N/A
N/A