The San Francisco Giants host the Chicago Cubs on August 28, 2025. First pitch from Oracle Park is scheduled for 3:45 p.m. EDT; the game will be broadcast on MARQ.
The Giants enter this series finale as -120 favorites with a 7.5 run total.
Find my MLB betting preview and Cubs vs Giants prediction below, as well as probable pitchers, betting trends, injury reports and more.
My Cubs vs Giants Prediction
- Cubs vs Giants picks: Under 7.5 (play to 6.5)
My Cubs vs Giants best bet is Under 7.5 with the best odds currently on DraftKings. Make sure to find the best odds by checking our live MLB odds page.
Cubs vs Giants Odds
| Cubs Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +163 | 7 -119o / -102u | -101 |
| Giants Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -209 | 7 -119o / -102u | -117 |
Cubs vs Giants Projected Starting Pitchers
| LHP Shota Imanaga (CHC) | Stat | RHP Logan Webb (SFG) |
|---|---|---|
| 8-6 | W-L | 12-9 |
| 1.3 | fWAR (FanGraphs) | 4.4 |
| 3.03/3.65 | ERA /xERA | 3.13/3.70 |
| 4.33/4.47 | FIP / xFIP | 2.60 |
| 0.94 | WHIP | 1.22 |
| 4.3 | K-BB% | 4.9 |
| 29.2 | GB% | 52.9 |
| 95 | Stuff+ | 105 |
| 109 | Location+ | 109 |
Sean Paul’s Cubs vs Giants Preview
San Francisco Giants Betting Preview
The Giants will hand the ball to their ace, Logan Webb, to round out this series versus the Cubs.
If Webb’s underlying numbers are any indicator, he’s due for a great finish to his season. San Francisco’s ace boasts a strong 3.13 ERA with a 2.60 FIP. He’s also been brilliant lately, holding four of his last five opponents to one or fewer runs and pitching 5 ⅔ innings or more in each outing.
Webb has flipped his approach from a full-fledged ground-baller to a ground-baller who strikes out 9.72 batters per nine. With the increased strikeouts, Webb has unlocked a new level in his game. He also walks 2.00 batters per nine and allows just 0.59 HR/9. So of the things that Webb can control, he typically puts San Francisco in a winning position.
The Giants' offense remains a major disappointment. They have over 65 million dollars committed this year to Willy Adames, Rafael Devers, and Matt Chapman, and that trio can't get rolling at the same time. Devers is the only one hitting well right now, as the Giants have the 19th-best wRC+ in August.
In this matchup, the Giants could struggle more than usual, as Devers and Jung Ho Lee are worse versus lefties. That's a matchup in the Cubs' favor since Devers hits .237 with seven of his 25 homers against southpaws, and Lee has a sub-700 OPS. Lee and Devers each have a wRC+ above 130 in August, but it won't be easy to keep up their hot streaks here.
Despite trading both Camilo Doval and Tyler Rogers, San Francisco has a terrific bullpen. Since the deadline, Ryan Walker has settled into an eighth-inning role and has yet to allow a run. Meanwhile, Randy Rodriguez has developed into a nice closer.
Chicago Cubs Betting Preview
While the Giants have a hurler who doesn't allow homers in Webb, the Cubs have a fly-ball specialist, Shota Imanaga, on the mound.
Imanaga has done well to evade possible regression. He has a 3.03 ERA, a 3.65 xERA, and a 4.33 FIP. Most of the damage done to Imanaga comes via the home run. Specifically look at his last two outings; he allowed two runs to Milwaukee on a two-run homer and allowed one run against the Pirates on a solo shot.
Deciding on when to back/fade Imanaga can often rest on which ballpark he's pitching in. In this matchup, Imanaga gets to pitch at Oracle Park, which ranks 27th in Statcast park factor. In particular, fly-balls that soar out of other parks go to die at the track in San Francisco, as only 75 balls have gone out of Oracle Park in 2025.
We've come to expect the Giants' offense to disappoint. It's another story for the Cubs to have a 78 wRC+, .219 average, and a .289 OBP in 25 games this month. For a chunk of the year, the Cubs had one of — if not the best offense in baseball. Now, not a single player other than Matt Shaw has a wRC+ better than 100 for almost a whole month.
Will it get better? Probably. It can't get any worse. However, we need to examine the current Cubs offense for this bet, and it's not a strong one. Plus, facing a pitcher like Webb, who can frustrate a struggling offense with his tough sinker, can make a game fly ball with a quickness.
Cubs vs Giants Prediction, Betting Analysis
Betting on the under for Giants home games has proven to be profitable. Before Wednesday's game, the total is 24-39-1 in favor of the under.
This feels like an easy under. We have a pair of strong pitchers dealing. Both offenses are pretty brutal and the ballpark is a total train wreck for hitters. I can't picture eight runs being scored in this one. I'd be surprised if this goes past six runs. It'll be a very, very low-scoring showdown.
Pick: Under 7.5 (play to 6.5)
Moneyline
No play
Run Line (Spread)
No play
Over/Under
I like the under
Cubs vs Giants Betting Trends
