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Yankees vs White Sox Prediction, Pick, MLB Odds for Tuesday, July 28

Yankees vs White Sox Prediction, Pick, MLB Odds for Tuesday, July 28 article feature image
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Nathan Ray Seebeck-Imagn Images. Pictured: Yankees SP Gerrit Cole

The Chicago White Sox host the New York Yankees on July 28, 2026. First pitch from Rate Field is scheduled for 7:40 p.m. ET. The game will be broadcast on YES.

The Yankees are favored by -131 on the moneyline and by -1.5 on the run line. The White Sox are +109 on the moneyline and +1.5 on the run line. The total is set at 8 runs.

Find my MLB picks and Yankees vs White Sox prediction below, as well as probable pitchers, weather report, and more.


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Yankees vs White Sox Prediction

  • Yankees vs White Sox Pick: Under 8 (-114)

My Yankees vs White Sox best bet is Under 8 total runs in this game. Make sure to find the best odds by checking our live MLB odds page.


Yankees vs White Sox Odds

Yankees Logo
Tuesday, Jul 28
7:40 p.m. ET
YES
White Sox Logo
Yankees Odds
SpreadTotalMoneyline
-1.5
+129
8
-105o / -114u
-131
White Sox Odds
SpreadTotalMoneyline
+1.5
-155
8
-105o / -114u
+109
Odds via DraftKings. Get up-to-the-minute MLB odds here.
DraftKings Logo
  • Yankees vs White Sox moneyline: Yankees -131, White Sox +109
  • Yankees vs White Sox over/under: 8 (-105o/ -114u)
  • Yankees vs White Sox spread: Yankees -1.5 (+129), White Sox +1.5 (-155)

Yankees vs White Sox Probable Pitchers

Gerrit Cole (RHP, NYY)StatAnthony Kay (LHP, CHW)
3-5W-L7-4
1.0fWAR (FanGraphs)0.5
3.92 / 3.53ERA / xERA4.21 / 5.33
3.92 / 3.71FIP / xFIP5.14 / 4.91
21.2K-BB%9.0
33.3GB%43.6
.273BABIP.278
103Stuff+104
106Location+102

Yankees vs White Sox MLB Betting Preview

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New York Yankees Betting Preview

The Yankees (60-46) are looking to build off a 9-5 win over the White Sox in the series opener. Despite playing without both Aaron Judge and now Cody Bellinger, the Bronx Bombers were able to erase a 3-0 deficit and pour on runs.

They're sending out right-hander Gerrit Cole, who has been sharp recently, which is why they're -136 road favorites.

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Chicago White Sox Betting Preview

The White Sox (55-50) cooled off after pouring on 12 runs vs. the Astros on Sunday. They've now lost three of their last four games, set for a tough spot against Cole and the Yankees.

Chicago is sending out Anthony Kay, who hasn't pitched deep into games this season, so Chicago will be forced to rely on their bullpen here.


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Yankees vs White Sox Pick, Betting Analysis

I'm riding with Yankees/White Sox Under 8.

Gerrit Cole has been on a nice roll lately. In his last three starts, he has a 3.36 xERA with a 33.7% strikeout rate and a 2.1% walk rate.

This is highlighted by a matchup against the Dodgers, where he shut down one of the best offenses in baseball, allowing two runs in six innings with one walk and eight strikeouts.

On the other side, the White Sox are going with lefty Anthony Kay. While his season-long numbers are unimpressive, Kay has given up two runs or fewer in five of his last six starts. He's also a lot better at home (3.06 ERA) than on the road (5.56 ERA).

Facing an undermanned Yankees lineup that is now without Cody Bellinger, I'm betting that Kay will provide a quality 5+ innings. Grant Taylor (2.25 xERA, 34.9 K%) didn't pitch for the White Sox yesterday, so he'll be available tonight, which also bodes well.

With that in mind, we'll bet on a lower-scoring game here.

Pick: Under 8 (-114, DraftKings)


Yankees vs White Sox Weather


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About the Author
Frank AmmiranteVerified Action Expert

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