The Chicago Cubs host the Cincinnati Reds on May 5, 2026. First pitch from Wrigley Field is scheduled for 7:40 p.m. ET. The game will be broadcast on MARQ.
The Cubs are favored by -170 on the moneyline and by -1.5 on the run line. The Reds are +140 on the moneyline and +1.5 on the run line. The total is set at 8 runs.
Find my MLB picks and Reds vs Cubs prediction below, as well as probable pitchers, weather report, and more.
Reds vs Cubs Prediction
- Reds vs Cubs Pick: Under 8 (-105)
My Reds vs Cubs best bet is Under 8 total runs in this game. Make sure to find the best odds by checking our live MLB odds page.
Reds vs Cubs Odds
| Reds Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -160 | 8 -115o / -105u | +140 |
| Cubs Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +135 | 8 -115o / -105u | -170 |
- Reds vs Cubs moneyline: Reds +140, Cubs -170
- Reds vs Cubs over/under: 8 (-115o / -105u)
- Reds vs Cubs spread: Reds +1.5 (-160), Cubs -1.5 (+135)
Reds vs Cubs Probable Pitchers
| LHP Andrew Abbott (CIN) | Stat | RHP Jameson Taillon (CHC) |
|---|---|---|
| 1-2 | W-L | 2-1 |
| 0.3 | fWAR (FanGraphs) | -0.2 |
| 5.97 / 5.20 | ERA / xERA | 4.41 / 4.11 |
| 4.93 / 4.61 | FIP / xFIP | 5.94 / 4.57 |
| 5.7 | K-BB% | 12.8 |
| 46.2 | GB% | 32.6 |
| .333 | BABIP | .207 |
| 92 | Stuff+ | 94 |
| 97 | Location+ | 99 |
Reds vs Cubs MLB Betting Preview
Editor's Note: This written article is a transcription from the latest episode of the Payoff Pitch podcast.
I'm going with Reds vs. Cubs Under 8 today.
The wind was blowing out at Wrigley Field for the past couple of days, but today it's blowing in, and it's also going to be 54 degrees. Should be a very run-suppressing environment there.
Even though Andrew Abbott will be on the mound for Cincinnati, and considering he's capable of walking anybody and imploding the under without the weather impacting anything, I do make this total about 7.5.
So, my pick is Under 8 at -110 or better between the Reds and the Cubs with the wind blowing in at Wrigley.
Pick: Under 8 (-105, BetMGM)
