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MLB Home Run Picks Today: 6 Player Props for Nationals vs Guardians, Mariners vs Athletics, More for Tuesday, May 26

MLB Home Run Picks Today: 6 Player Props for Nationals vs Guardians, Mariners vs Athletics, More for Tuesday, May 26 article feature image
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Credit:

May 24, 2026; Kansas City, Missouri, USA; Seattle Mariners center fielder Julio Rodriguez (44) rounds the bases after hitting a home run during the first inning against the Kansas City Royals at Kauffman Stadium. Mandatory Credit: Jay Biggerstaff-Imagn Images

Happy Dinger Tuesday! I've got some bangers.

Read on for my 6 home run picks today for Tuesday, May 26.


MLB Home Run Picks Today

GameTime (ET)Pick
Washington Nationals LogoCleveland Guardians Logo
6:10 PM
Los Angeles Angels LogoDetroit Tigers Logo
6:40 PM
Cincinnati Reds LogoNew York Mets Logo
7:10 PM
Minnesota Twins LogoChicago White Sox Logo
7:40 PM
Houston Astros LogoTexas Rangers Logo
8:05 PM
Seattle Mariners LogoOakland Athletics Logo
9:40 PM
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our MLB Odds page, which automatically surfaces the best lines for every game.


Nationals vs Guardians Prediction

Washington Nationals Logo
Tuesday, May 26
6:10 PM ET
MLB.TV
Cleveland Guardians Logo
James Wood Home Run
FanDuel Logo

Wood has been one of the best power hitters in the league this season, and despite this being a lefty/lefty matchup, these odds are far too high.

Joey Cantillo is a reverse-splits pitcher when it comes to power, allowing a 1.33 HR/9.

This ballpark is above average for power, and I have the true odds here around +350, making this a great bet.

Pick: James Wood Home Run



Angels vs Tigers Player Prop

Los Angeles Angels Logo
Tuesday, May 26
6:40 PM ET
MLB.TV
Detroit Tigers Logo
Mike Trout Home Run
FanDuel Logo

While I prefer betting lefties vs. Keider Montero, this is a plus matchup for the Angels righties, and their odds are far too high.

Montero has allowed an above-average 1.32 HR/9 in his career to righties and grades out as an above-average matchup for righty power.

Trout has had some of the best underlying power numbers of his career this season, and I have the true odds here around +320, making this a great bet.

Pick: Mike Trout Home Run



Reds vs Mets Home Run Pick

Cincinnati Reds Logo
Tuesday, May 26
7:10 PM ET
MLB.TV
New York Mets Logo
Juan Soto Home Run
FanDuel Logo

Chase Burns is one of the better young pitchers in the league, but his strikeout stuff is largely negated by Soto, and Burns has struggled heavily with lefty power, allowing a career 1.60 HR/9.

This ballpark isn't great for power, but with the wind blowing out tonight, the ball should be flying well.

Soto is one of the best power bats in the league, and I have the true odds here around +350, making this a great bet.

Pick: Juan Soto Home Run



Twins vs White Sox Pick

Minnesota Twins Logo
Tuesday, May 26
7:40 PM ET
MLB.TV
Chicago White Sox Logo
Colson Montgomery Home Run
FanDuel Logo

Montgomery has been one of the best HR hitters in the league since getting called up, and these odds are far too high.

The weather should be slightly below average for hitting, but the matchup vs. Joe Ryan is a plus for lefty power.

Ryan is an extreme fly-ball pitcher with above-average splits.

He grades out as a matchup that is well above average for lefties, and I have the true odds here around +300, making this a great bet.

Pick: Colson Montgomery Home Run



Astros vs Rangers Best Bet

Houston Astros Logo
Tuesday, May 26
8:05 PM ET
MLB.TV
Texas Rangers Logo
Yordan Alvarez Home Run
FanDuel Logo

Yordan is in an average spot, and there is no way that he should be over +300 in an average spot.

This ballpark is below average for HRs, but Jack Leiter grades out as a plus matchup for lefty power.

I have the true odds here around +280, making this a great bet.

Pick: Yordan Alvarez Home Run



Mariners vs Athletics Prediction

Seattle Mariners Logo
Tuesday, May 26
9:40 PM ET
MLB.TV
Oakland Athletics Logo
Julio Rodriguez Home Run
FanDuel Logo

The matchup is around average for power going up against Luis Severino, but this ballpark is a huge upgrade for J-Rod, and these odds are far too high.

Sutter Health Park is one of the best parks in the league for power, and J-Rod has been in great form recently.

After a slow start to the season, he has turned things around, and when he gets going, he tends to keep going.

I have the true odds here around +425, making this a great bet.

Pick: Julio Rodriguez Home Run



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About the Author
Grant NeifferVerified Action Expert

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