We have a full, 15-game slate to celebrate this holiday, starting early with Twins vs. Yankees at 1:35 p.m. ET and finishing with Padres vs. Dodgers at 10:10 p.m. ET.
As always, I've got some bangers for you, selecting players from five of those matchups.
Read on for my 5 MLB Home Run Picks Today.
MLB Home Run Picks Today
In the table below, you'll find each of Grant Neiffer's top Home Run prop picks from today's slate of games. Click on any pick or team logo to navigate to a specific bet discussed in this article.
| Game | Time (ET) | Pick |
|---|---|---|
  | 1:35 PM | |
  | 4:10 PM | |
  | 7:10 PM | |
  | 8:08 PM | |
  | 8:10 PM | |
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our MLB Odds page, which automatically surfaces the best lines for every game. | ||
Twins vs Yankees Prediction, Pick
Twins starter Zebby Matthews is a gas can for power, and the ballpark is one of the best in the league for lefty power hitters, such as Trent Grisham.
The weather is incredible for hitting, with temperatures in the high 90s and wind blowing out at 10 MPH. I have the true odds on the Yankees DH at around +220.
Pick: Trent Grisham Home Run
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Blue Jays vs Mariners Prediction, Pick
Kazuma Okamoto gets an above-average matchup for righty power with Logan Gilbert and Emerson Hancock piggybacking today on the Mariners' mound.
Both are plus matchups for righty power, and although the ballpark is a downgrade, I have the true odds on the Blue Jays 3B at around +350.
Pick: Kazuma Okamoto Home Run
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Rays vs Astros Prediction, Pick
The spot here is an average one, which is more than enough to justify betting Yordan Alvarez at these odds.
He is one of the best home run hitters in the league and has been incredible this season.
I have the true odds on the Astros DH at around +250.
Pick: Yordan Alvarez Home Run
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Mets vs Braves Prediction, Pick
This is strictly a price play. Mets SP Sean Manaea is a below-average matchup for lefty power, but the weather is a big plus for power, with temperatures in the low 90s.
Matt Olson is one of the best homer hitters in the league, and I have the true odds for the Braves 1B at around +350.
Pick: Matt Olson Home Run
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Giants vs Rockies Prediction, Pick
Giants starter Robbie Ray is a gas can for power at this point in his career, giving up an above-average number of HRs to righties despite playing in the most pitcher-friendly ballpark in the league.
The weather is good over in Coors Field, and the ballpark is one of the best in the league for home runs.
Hunter Goodman is one of the best power hitters in the league, and I have the true odds for the Rockies catcher at around +200.
Pick: Hunter Goodman Home Run
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